1.The anaylsis of clinical contents of outpatient in family medicine department at a general hospital.
Myung Eui HONG ; Dong Suk KANG ; In Ja HUH ; Jong Ho SUH
Journal of the Korean Academy of Family Medicine 1993;14(8):608-613
No abstract available.
Hospitals, General*
;
Humans
;
Outpatients*
2.A comparative study of geriatric diseases in rural and urban areas.
Hye Soon RHEE ; Youn Seon CHOI ; Eui Jung HWANG ; Myung Ho HONG
Journal of the Korean Academy of Family Medicine 1991;12(1):36-46
No abstract available.
3.A clinical study on attempted suicide with drug in the rural area.
Mong Ha PARK ; Yong Kyun ROH ; Jae Hweon KIM ; Eui Jung HWANG ; Myung Ho HONG
Journal of the Korean Academy of Family Medicine 1991;12(1):22-29
No abstract available.
Suicide, Attempted*
4.Relationship between Insight and Manic Symptoms in Stable Patients with Chronic Schizophrenia
Eui Seok LEE ; Narei HONG ; Myung Hun JUNG ; Hyun Joo HONG ; Duk In JON
Mood and Emotion 2018;16(2):103-107
OBJECTIVES: Patient insight is a very important factor in the management of schizophrenia. Manic symptoms can occasionally be identified by the patient, even in cases of schizophrenia. The aim of this study is to examine the relationship among patient insight, the psychotic and manic symptoms, and the demographic clinical variables.METHODS: Seventy-four participants (male 44, female 30) with chronic schizophrenia in community mental health facilities were evaluated according to the Korean version of the Scale to assess Unawareness of Mental Disorder (SUMD-K), the Korean version of Mood Disorder Questionnaire (K-MDQ), and the Brief Psychiatric Rating Scale (BPRS).RESULTS: The mean number of previous admissions was 3.85. The mean CGI-S score was 3.8 and a significant negative correlation (r=0.26) was shown with “awareness of mental disorder”. Thirty-five percent of subjects were K-MDQ positive (cutoff point=7 or more). Among the SUMD-K, “awareness of effect of medication” showed a significant negative correlation (r=−0.33) with the total K-MDQ score, but not with the total BPRS score. The negative correlation was more obvious in participants with negative K-MDQ (total K-MDQ score 6 or less, r=−0.31).CONCLUSION: A possible relationship was observed between these manic symptoms and patient insight. Identification of manic symptoms in schizophrenia would be considerable in a clinical setting.
Brief Psychiatric Rating Scale
;
Female
;
Humans
;
Mental Disorders
;
Mental Health
;
Mood Disorders
;
Schizophrenia
5.Application of Feedback Education to the Progression Notes Written by Medical Students in Surgical Clerkship.
Sang Uk HAN ; Eui Young SOH ; Jung HONG ; Tae Seung LEE ; Myung Wook KIM
Korean Journal of Medical Education 2000;12(2):173-180
BACKGROUND: Progression note is a critical source in patient care. It is used to evaluate physician performance as well as the quality of clinical care. However, the majority of medical schools do not formally teach how to write progression notes. Therefore, the purpose of this research was to determine the impact of feedback education on the quality of the students' progression notes. METHODS: A static group-comparison design was used to determine the quality of progression notes written by 64 students. 31 students received feedback, but the other 33 students did not. 219 patients' progression notes were selected for this study. Progression notes were blindly reviewed by the 3 faculty members. RESULTS: Progression notes from students who received feedback showed significantly higher scores than those students who did not received feedback(p<0.05). CONCLUSIONS: Our findings suggest that feedback education in writing progression notes needs to be integrated to improve quality of the notes.
Education*
;
Humans
;
Patient Care
;
Schools, Medical
;
Students, Medical*
;
Writing
6.First Case of Mycobacterium longobardum Infection.
Sung Kuk HONG ; Ji Yeon SUNG ; Hyuk Jin LEE ; Myung Don OH ; Sung Sup PARK ; Eui Chong KIM
Annals of Laboratory Medicine 2013;33(5):356-359
Mycobacterium longobardum is a slow-growing, nontuberculous mycobacterium that was first characterized from the M. terrae complex in 2012. We report a case of M. longobardum induced chronic osteomyelitis. A 71-yr-old man presented with inflammation in the left elbow and he underwent a surgery under the suspicion of tuberculous osteomyelitis. The pathologic tissue culture grew M. longobardum which was identified by analysis of the 65-kDa heat shock protein and full-length 16S rRNA genes. The patient was cured with the medication of clarithromycin and ethambutol without further complications. To the best of our knowledge, this is the first report of a M. longobardum infection worldwide.
Aged
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Anti-Bacterial Agents/therapeutic use
;
Bacterial Proteins/genetics
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Chaperonin 60/genetics
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Clarithromycin/therapeutic use
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Elbow/pathology
;
Ethambutol/therapeutic use
;
Humans
;
Male
;
Mycobacterium Infections, Nontuberculous/*microbiology
;
Nontuberculous Mycobacteria/classification/genetics/*isolation & purification
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Osteomyelitis/diagnosis/drug therapy/*microbiology/pathology
;
RNA, Ribosomal, 16S/genetics
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Treatment Outcome
7.Prediction of Complicated Acute Cholecystitis During Emergency Department Stay.
Hong In PARK ; Jae Wook PARK ; Myung Bo SHIM ; Jin Kun BAE ; Sang Mo JE ; Tae Nyoung CHUNG ; Eui Chung KIM ; Sung Wook CHOI ; Ok Jun KIM
Journal of the Korean Society of Emergency Medicine 2015;26(4):320-325
PURPOSE: The aim of the study was to determine the factors associated with complicated acute cholecystitis of initial clinical findings during an emergency department (ED) visit, and to use them as a guideline for consideration of early and active surgical intervention, to improve the prognosis of acute cholecystitis. METHODS: Medical records of adult patients diagnosed and treated in the ED as acute cholecystitis were reviewed retrospectively. Clinical findings including demographic data, past medical history, symptoms, physical exam, and laboratory test results were included in the analysis. A case associated with gall bladder empyema, gangrene, perforation, hydrops, or failure of initial laparoscopic approach was defined as complicated acute cholecystitis. Factors showing significance in univariate analyses were included in binary logistic regression analysis for prediction of complicated acute cholecystitis. RESULTS: Age, sex, hypertension history, anorexia, body temperature, white blood cell count (WBC), aspartate aminotransferase, creatinine, total bilirubin, amylase, and lipase were significant in univariate analyses, and included in multivariate analysis. Age (p=0.039), male sex (p=0.004), and WBC (p=0.019) were significant in multivariate analysis. CONCLUSION: Age, sex, and initial WBC of patients diagnosed and treated in the ED as acute cholecystitis were independently associated with complicated acute cholecystitis.
Adult
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Amylases
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Anorexia
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Aspartate Aminotransferases
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Bilirubin
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Body Temperature
;
Cholecystitis
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Cholecystitis, Acute*
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Creatinine
;
Edema
;
Emergencies*
;
Emergency Service, Hospital*
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Gangrene
;
Humans
;
Hypertension
;
Leukocyte Count
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Lipase
;
Logistic Models
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Male
;
Medical Records
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Multivariate Analysis
;
Prognosis
;
Retrospective Studies
8.Chlamydia pneumoniae(Cp) infection, is that a risk factor of atherosclerosis?: On the basis of seroepidemiologic study.
Young Goo SONG ; Jung Myung KIM ; Hyuck Moon KWON ; Eui Young CHOI ; Gil Jin JANG ; Bum Kee HONG ; Hyun Sook KIM ; Hyun Seung KIM
Korean Journal of Medicine 2000;58(4):411-419
BACKGROUND: Several risk factors of atherosclerosis have been known. However, many patients have been experienced coronary heart disease without known risk factors of atherosclerosis, and it has been suggested that some kinds of infections may be associated with atherosclerosis as risk factors. Among many candidate infectious agents, Chlamydia pneumoniae (Cp) has been showing a positive relationship with atherosclerosis. Therefore, we investigated massive serologic study using a ELISA for detection of Cp to identify the relationship with atherosclerosis as a risk factor. METHODS: Serologic tests were done in patients who were performed coronary angiogram among patients with typical symptoms of angina and with positive results in non- invasive test (EKG, Treadmill) from May 1997 to September 1998. Among them, patients with luminal narrowing of more than 50% in at least one vessel were grouped into 'Case group (Group I)' and patients with normal coronary arteries or minimal lesion were grouped into 'Positive control group(Group II)'. We also studied healthy persons, as a 'Negative control group (Group III), who had not experienced any symptoms related with coronary heart disease and had normal EKG findings. Serologic tests for Cp-IgG and Cp-IgA were performed by ELISA. RESULTS: There was no statistical difference in seropositive rate between Group I and II, but seropositive rate of Group III was statistically lower than those of Group I or II for Cp-IgG, Cp-IgA, and both, respectively. But multivariate analysis by using logistic regression showed no statistcal differences between groups. Subgrouping by several traditional risk factors, seropositive rate for Cp-IgG and both IgG and IgA, was significantly different between Group I and III in patients without traditional risk factors of atherosclerosis, such as, females, non-smokers, normotension, non-diabetes, normal cholesterol level, and high HDL-cholesterol level. For Cp-IgA, however, the difference was observed in normotension, non-diabetes, and in normal cholesterol level. In multivariate analysis, seropositive rate for Cp-IgG and both IgG and IgA was significantly different between Group I and III in females and non-smokers, but not for the Cp-IgA. CONCLUSIONS: These results suggest that Cp infection might be an independent risk factor of atherosclerotic coronary disease, particularly in patients without traditional risk factors of atherosclerosis. Further study with coronary tissue should be continued.
Atherosclerosis*
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Chlamydia*
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Chlamydophila pneumoniae
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Cholesterol
;
Coronary Disease
;
Coronary Vessels
;
Electrocardiography
;
Enzyme-Linked Immunosorbent Assay
;
Female
;
Humans
;
Immunoglobulin A
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Immunoglobulin G
;
Logistic Models
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Multivariate Analysis
;
Phenobarbital
;
Risk Factors*
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Seroepidemiologic Studies*
;
Serologic Tests
9.Expression of leptin receptor (Ob-R) in human atherosclerotic lesions: potential role in intimal neovascularization.
Seok Min KANG ; Hyuck Moon KWON ; Bum Kee HONG ; Dongsoo KIM ; In Jai KIM ; Eui Young CHOI ; Yangsoo JANG ; Hyun Seung KIM ; Myung Sin KIM ; Hyuck Chan KWON
Yonsei Medical Journal 2000;41(1):68-75
Neovascularization of the adventitial vasa vasorum with extension into the intima of atherosclerotic lesions is frequently observed, but its pathophysiological significance is still subject to debate. Recently, leptin, the product of the Ob gene, was identified. Leptin, via activation of the endothelial receptor (Ob-R), generates a growth signal involving a tyrosine kinase-dependent intracellular pathway and promotes angiogenic processes. We hypothesized that a high concentration of leptin within vasa vasorum and plaque itself, may influence inflammatory and vascular neovascularization coupling with functional upregulation of the vascular endothelial growth factor (VEGF). Microscopic computerized tomography was utilized for the spatial distribution of vasa vasorum and intimal neovascularization from atherosclerotic human coronary arteries. Atherosclerotic coronary arteries showed a dense plexus of microvessels in the adventitia and plaque itself. Microscopic analysis from human atherosclerotic aortas revealed an increase in the intimal thickness with neovascularization. The immunoreactivity for Ob-R, VEGF and matrix metalloproteinase (MMP) increased in atherosclerotic plaque, predominantly in the endothelial lining of the intimal neovessel and macrophages/foam cells. Our observation of a prominent colocalization between Ob-R, VEGF and MMP supports this hypothesis and these factors participate in the neovascularization of atherosclerotic lesions. The present study is the first report on vascular tissue and it opens a promising perspective concerning future investigations of leptin-dependent modulation of atherogenesis and vascular neovascularization under pathophysiolgical conditions.
Adult
;
Arteriosclerosis/physiopathology
;
Arteriosclerosis/pathology
;
Arteriosclerosis/metabolism*
;
Blood Vessels/pathology
;
Blood Vessels/metabolism
;
Carrier Proteins/physiology
;
Carrier Proteins/metabolism*
;
Human
;
Middle Age
;
Neovascularization, Pathologic/physiopathology
10.At Which Stage of Gastric Cancer Progression Do Levels of Carcinoembryonic Antigen and Carbohydrate Antigen 19-9 Increase? Application in Advanced Gastric Cancer Treatment.
Eui Soo HAN ; Han Hong LEE ; Jun Suh LEE ; Kyo Young SONG ; Cho Hyun PARK ; Hae Myung JEON
Journal of Gastric Cancer 2014;14(2):123-128
PURPOSE: Since there are no proven tumor markers that reflect the course of gastric cancer, carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) are commonly used alternatives. However, the degree of progression that corresponds to an increase in these markers, and the values of these markers at different cancer stages, remains unclear. MATERIALS AND METHODS: This study enrolled 1,733 gastric cancer patients who underwent surgery and whose pre-operative CEA and CA19-9 levels were known. Survival curves and mean values of the two markers were compared according to the degree of cancer progression: serosa-unexposed (SU), serosa-exposed (SE), direct invasion (DI), localized seeding (P1), and extensive seeding (P2). RESULTS: The 5-year overall survival rates at each stage differed significantly, except between DI and P1 patients (17.1% vs. 10.5%, P=0.344). The mean CEA values in SU, SE, DI, P1, and P2 patients were 5.80, 5.48, 13.36, 8.06, and 22.82, respectively. The CA19-9 values for these patients were 49.40, 38.97, 101.67, 73.77, and 98.57, respectively. The increase in CEA in P2 patients was statistically significant (P=0.002), and the increases in CA19-9 in DI and P2 patients were significant (P=0.025, 0.007, respectively). There was a fair correlation between the two markers in P2 patients (r=0.494, P<0.001). CONCLUSIONS: CA19-9 can be used to assess DI of gastric cancer into adjacent organs. Both markers are useful for predicting the presence of extensive peritoneal seeding.
Carcinoembryonic Antigen*
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Carcinoma
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Disease Progression
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Humans
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Neoplasm Invasiveness
;
Stomach Neoplasms*
;
Survival Rate
;
Biomarkers, Tumor