OBJECTIVE:To establish the quality standard of Tangkang capsule. METHODS:Momordica charantia L. and Euonymus alatus(Thunb.)Sieb.,the main ingredients in Tangkang capsule including were identified by TLC, meanwhile, the content of total Momordica charantian saponin was determined by UV-Vis. RESULTS: The TLC spots were clear and the separation degree was good. The linear range of Ginsenoside Rg1 was 72～252 ?g(r=0.999 7) with average recovery rate at 100.68% (RSD=1.43%,n=6). CONCLUSION: The established quality standard can be used for the quality control of this Tangkang capsule.

Objective　To investigate the causes of recurrent spontaneous abortion(RSA) and to know the relation between RSA and antiphospholipid thrombosis syndrome(APL-T). Methods　ELISA and PTT-LA were used to detect anticardiolipin antibody(ACA) and lupus anticoagulant(LA) in 32 patients with RSA and 20 normal controls(NC). Results　There were 17 positive of antiphospholipid antibody(APA) in RSA group. The incidence was significantly higher than that in NC group. The incidence of LA was also significantly higher than that in NC group. 8 patients were diagnosed as APL-T. Conclusion　LA may be the more important reason of RSA. It should be considered as APL-T when RSA is unexplained.

Objective To observe the efficacy of bioelectric stimulation of the pelvic floor combined with acupuncture in treating detrusor urine weakness after transurethral resection of the prostate (TURP) in patients with prostate hyperplasia.Methods Forty-seven cases with detrusor urine weakness after TURP were randomly divided into an experimental group and a control group.All of the patients received routine bladder function training and medication.In addition,patients in the experimental group were treated with bioelectric stimulation of the pelvic floor and with acupuncture.The differences between the two groups were compared using the International Prostate Symptom Score (IPSS),maximum urine flow rate (MFR),average flow rate (AFR),detrusor pressure at peak flow (PdetQmax) and residual urine volume in the bladder.Results No significant difference was found between the two groups before treatment,but at two weeks after treatment MFR,AFR and PdetQmax were significantly higher in the experimental group than in the control group,and residual urine volume and IPSS were significantly lower.Conclusion Bioelectric stimulation of the pelvic floor combined with acupuncture is more effective than routine bladder function training and medication alone for alleviating detrusor urine weakness after TURP.

Objective Compared with surgical operation,to investigate the clinical efficacy and advantages of interventional treatment in blunt liver traum.Methods 32 patients from July 2010 to October 2012,who were diagnosed as blunt liver trauma,received super selective hepatic artery embolization in Chinese People's Liberation Army in 98th Hospital.Another 27 ones received operation at the same time in Peolies's Liberation Army 98th (AAST grade Ⅱ to Ⅳ).Retrospective analysis of related cases was presented.The results were analyzed by t test.Results All of 32 patients that received super selective hepatic artery embolization were stanched bleeding successfully.All patients were followed up for 3 to 18 months,the mean follow-up time was 10 months,with no severe complications occurred or no lost cases.Conclusions Compared with surgical operation,interventional treatment had advantage that included eliable hemostasis,less operation time,minimally invasive and less hospitalization time.Interventional treatment had good effects on blunt liver trauma which were AAST grade Ⅱ to Ⅲ.

China ; Humans ; Practice Guidelines as Topic ; Rhinitis, Allergic ; diagnosis ; therapy

Object To investigate the expression of inducible nitric oxide synthase(iNOS) and vascular endothelial growth factor(VEGF) in human esophageal squamous cell carcinoma and their clinical significances,and to evaluate the correlation between the expression of iNOS and VEGF.Methods Immunohisto-chemical SABC methond was used to detect the expression of iNOS and VEGF in 52 cases of esophageal squamous cell carcinoma and 20 cases of paired para-carcinama.The correlation between the expression of iNOS and VEGF was analyzed statistically.And the correlation between the expression of iNOS and VEGF and the clinical pathological features of the patients was analyzed statistically.Results The positive expression rates of iNOS and VEGF in esophageal squamous cell carcinoma were 63.46％ (33/52) and 67.31％ (35/52),respectively.The positive expression rates of iNOS and VEGF in paired para-carcinama tissues were 10％ (2/20) and 20％ (4/20)respectively.The positive expression rates of iNOS and VEGF in esophageal squamous cell carcinoma were significantly higher than those in paired para-carcinama tissues(x2 =14.455 6,P ＜ 0.01;x2 =9.508 9,P ＜ 0.01).There was significiat correlation between the expression of iNOS,VEGF and the pathological grade (P ＜ 0.01),clinic TNM stage(P ＜ 0.05),lymph noed metastasis(P ＜ 0.05),but there was no correlation between the expression of iNOS,VEGF and the patients sex (P ＞ 0.05).Expression of iNOS was positively correlated with that of VEGF(r=0.748 2,P ＜ 0.01).Conclusion iNOS and VEGF are highly expressed and correlated in esophageal carcinoma.It is speculated that a common activation mechanism may coexists between the two genes.The expression of iNOS and VEGF plays an important role in the malignant progression.

Asthma is a chronic inflammatory airway disease,the goal of treatment is achieving total control.The correct diagnosis is a prerequisite for evaluating asthma control.A number of factors contribute to suboptimal asthma control,individuals may have different response to the same anti-asthmatic drug due to genetic variations,co-morbid rhinitis is often lead to poor control,there are also a lot of triggers may influence asthma control including respiratory viral infection,allergens,food,climatic change.Moreover,parental asthma perception,adherence,and proper use of inhaler device are critical for asthma control.Appropriate prescribing of antibiotics were also a big problem in the treatment of childhood asthma.Enhance the knowledge of asthma control influencing factors will make a better control for asthmatic children.

OBJECTIVE: To analyze the pathogenesis and clinical manifestations of delayed encephalopathy after acute carbon monoxide poisoning, and to investigate the method of complex treatment and the factors influencing prognosis.DATA SOURCE: Related papers were searched by computer in Chinese Journal Full-text Database (CJFD) from January 1983 to October 2000 and CBMdise with the terms of "acute, carbon monoxide poisoning, delayed,encephalopathy", and the language of paper was limited to Chinese.STUDY SELECTION: The papers relevant to the pathogenesis, clinical manifestation, treatment and prognosis of acute carbon monoxide poisoning were collected preliming screening. Inclusion criteria: ① Randomized controlled trial. ② Blind method was not restricted. Exclusion criteria: The same researches repeated.DATA EXTRACTION: A total of 240 pieces of paper related to acute carbon monoxide poisoning induced eneephalopathy were collected, among which, 24 pieces accorded with inclusion criteria.DATA SYNTHESIS: The pathogenesis of acute carbon monoxide poisoning induced encephalopathy was relatively complex, which should be deeply recognized from the clinical manifestations such as symptom, sign,electroencephalogram, cerebral CT and MRL The therapeutic methods included ①Neural cell agonist, vasodilator, anticoagulant and vitamin ②High pressure oxygen ③ Ultraviolet blood irradation and oxygenation, UBIO. ④ Acupuncture therapy. The factors influencing prognosis of delayed encephalopathy after acute carbon monoxide poisoning were usually related to age, degree of poisoning, complications and cure time.CONCLUSION: Acute carbon monoxide poisoning can cause encephalopathy, which is the result of multiple pathogenesis. There is no special treatment for it until now, and complex treatment should be used, but the curative effect is not ideal, and intellectual disturbance and extremity function disorder of different degree might be left after treatment, and agrypnocoma would exist for a long time.

Objective To analyze the clinical efficacy and safety of coronary intervention in elderly patients with coronary heart disease.Methods Totally 163 middle and aged patients with coronary heart disease in our hospital were involved in this study.Clinical data of them were analyzed.Patients were divided into groups aged 75 87 years (n=64),and aged 42 74 years (n=99).After coronary artery disease (CAD) degree assessment,patients were treated with angiography and coronary intervention.Clinical efficacy and complications were compared between groups.Results All patients underwent coronary angiography.The multivessel and complex lesions were more common in aged 75-87 years of CAD patients than in aged 42-74 years of CAD patients (P＜0.05).There were significant differences in operation success rate,incidence of complications and mortality during hospitalization between the the above groups [97.0％ (96 cases) vs.87.5％ (56 cases),4.0 (4 cases) vs.12.5 (8 cases),1.0％ (1 case) vs.10.9％ (7 cases),x2=5.54,4.08,8.21,respectively,all P＜0.05].Conclusions The clinical efficacy and safety of coronary intervention is correlated with age in patients with coronary heart disease.

Problem-based learning ( PBL ) has become the major teaching method to cultivate medical student's autonomous learning and their ability to solve problems.It's basic elements are the scene authenticity and problem construction.Thoratic surgery clinical probation is the most important part of clinical teaching.The author summerized and analysized the PBL teaching experience in thoratic surgery and had some new understanding and experience on the problem construction,and therefore made some exploration and improvement to it and got some good teaching effect.