1.Availability of creamatocrit in breast milk jaundice.
Mi Jung KIM ; Hye Kyung HAN ; Mi Na LEE
Korean Journal of Perinatology 1993;4(1):29-36
No abstract available.
Breast*
;
Jaundice*
;
Milk, Human*
2.Chronic Fatigue Syndrome.
Yeungnam University Journal of Medicine 2007;24(1):1-10
The chronic fatigue immune dysfunction syndrome (abbreviated CFIDS or CFS) is a disorder characterized by debilitating fatigue(over 6 months), along with cognitive, musculoskeletal, and sleep abnormalities. The etiology of this illness is unlikely to be a single agent. Findings to date suggest that physiological and psychological factors work together to predispose and perpetuate the illness. Diagnosis is made difficult by the nonspecific clinical findings and no available diagnostic testing. With no known cause or cure for the chronic fatigue and immune dysfunction syndrome, treatment is based on relieving symptoms and improving the quality of life of affected patients. There is emerging evidence that chronic fatigue syndrome may be familial. In the future, studies will examine the extent to which genetic and environmental factors play a role in the development of chronic fatigue syndrome. Most patients with CFS have psychiatric problems such as a generalized anxiety disorder, or major or minor depression, therefore, these mental health disorders may be correlated with the pathophysiology of the CFS. The treatment for CFS must be individualized, due to the heterogeneity of the CFS population. Also the treatment of CFS is built on a foundation of patient-physician relationship, respect and advocacy.
Anxiety Disorders
;
Depression
;
Diagnosis
;
Diagnostic Tests, Routine
;
Fatigue
;
Fatigue Syndrome, Chronic*
;
Humans
;
Mental Health
;
Population Characteristics
;
Psychology
;
Quality of Life
3.A Case of Epidermolysis Bullosa Dystrophica Dominant.
Mi Jung JUNG ; Jong Seok LEE ; Young Keun KIM
Korean Journal of Dermatology 1994;32(3):518-522
Epidermolysis bullosa dystrophica is rare, chronic non-inflammtory mechanobullous disease of hereditary trait, which easily produces bullae by minor trauma or sponta neosly. A 1-day old male neonate presented wide spread vesicobullous minor, eruptions since birth. On examination, tense bullse were noted on the dorsa of the feet and right knei: area Which is usually serous but may be hemarrhagic tendeney. This was healed by the dropping of oxoline and wet betadine auze application along with the administration of vitamin E and phenytoin. We present a case of epidermolysis bullosa dystrophica that seems be a dominant type considering the presence of family history with histopathologic and electron microscopic findings.
Epidermolysis Bullosa Dystrophica*
;
Epidermolysis Bullosa*
;
Foot
;
Humans
;
Infant, Newborn
;
Male
;
Parturition
;
Phenytoin
;
Povidone-Iodine
;
Transcutaneous Electric Nerve Stimulation
;
Vitamin E
;
Vitamins
4.Loss of Heterozygosity of p73, APC, and p53 in Hepatoblastoma.
Han Seong KIM ; Young Mi JUNG ; Mi Ran KIM ; Jung Young LEE ; Mi Sook LEE ; Ja June JANG
The Korean Journal of Hepatology 1999;5(1):43-49
BACKGROUND/AIMS: The status of tumor suppression gene can be assessed indirectly by analyzing the loss of heterozygosity. Hepatoblastoma is a malignant liver tumor in childhood. To find the molecular carcinogenetic mechanism of hepatoblastoma, loss of heterozygosity (LOH) of p73, APC and p53 was studied. MATERIALS AND METHODS: Hepatoblastoma tissues from thirty-three cases were collected by lobectomy or tumorectomy. On H- stained sections, normal and tumor cells were microdissected separately and LOH analysis was perfomed using 8 markers: six of p73, one of APC and one of p53. RESULTS: Number of cases showing at least one LOH in six p73 markers was four out of twenty- six (15.4%): each LOH frequencies in D1S160, D1S170, D1S199, D1S228, D1S243 and D1S253 were in order of 7.7%, 0%, 9.1%, 0%, 12.5% and 0%. LOH frequency of APC was 41.7% and that of p53 was 13.3%. CONCLUSION: Low LOH frequency of p73 related markers indicates that p73 gene may not be implicated in carcinogenesis of hepatoblastoma.
Carcinogenesis
;
Hepatoblastoma*
;
Liver
;
Loss of Heterozygosity*
5.Factors Affecting to Bone Mineral Density in Postmenopausal Women.
Seung Pil JUNG ; Keun Mi LEE ; Suk Hwan LEE
Yeungnam University Journal of Medicine 1996;13(2):261-271
INTRODUCTION: Osteoporosis, the most common metabolic bone disorder, is a condition of reduced bone density and increased susceptibility to fractures. Osteoporosis is a major public health problem and a significant cause of morbidity in postmenopausal women. Therefore family physicians as primary care physicians are in a key position for preventing and treating this disorder. So we studied the factors affecting to bone mineral density in postmenopausal women. MATERIALS AND METHODS: A total of 136 spontaneous postmenopausal women were participated in the study. They have measured spinal bone mineral density by dual energy x-ray absorptiometry from January 1992 to June 1995 at Yeungnam University Hospital. Age, height, weight, age at menarche and menopause, number of child and breast feeding child, history of oral pill ingestion, family history of osteoporosis, amount of milk and coffee ingestion, consumption of tobacco and alcohol and physical activity were assessed by qustionnaire and medical records. RESULTS: physical activity and weight were significant contributors. Physical activity is most the largest contributor. CONCLUSIONS: Among factors affecting to BMD in postmenopausal women, physical activity and weight were more important factors. Therefore continuous physical activity is significant factor to prevent osteoporosis in postmenopausal women.
Absorptiometry, Photon
;
Bone Density*
;
Breast Feeding
;
Child
;
Coffee
;
Eating
;
Female
;
Humans
;
Medical Records
;
Menarche
;
Menopause
;
Motor Activity
;
Osteoporosis
;
Physicians, Family
;
Physicians, Primary Care
;
Public Health
;
Tobacco
6.Interaction between HIV-1 Nef and LyF-1, the T Cell Specific Transcription Factor.
Mi Seon LEE ; Kyoung Hoa LEE ; Jung Woo KIM
Journal of the Korean Society of Virology 2000;30(3):211-217
No Abstract Available.
HIV-1*
;
Transcription Factors*
7.Factors Influencing Level of Health Literacy of Migrant Workers in Korea.
Journal of Korean Academy of Fundamental Nursing 2013;20(3):269-277
PURPOSE: The purposes of the study were to identify level of health literacy and factors influencing health literacy of migrant workers. METHODS: Data were collected using a cross sectional correlational design. Participants were 128 migrant workers in Korea. Data were analyzed using descriptive statistics, independent t-test, ANOVA, Scheffe test, and hierarchical multiple regression with the SPSS 18.0 program. RESULTS: The health literacy level of migrant worker was low and they had difficulty in understanding patient education materials and medical forms. Factors influencing health literacy were residential areas (city or rural), education level, length of stay in Korea, and ability to understand spoken Korean. Regression model accounted for 14.2% of the variance in health literacy. CONCLUSION: Lower levels of health literacy make it difficult for migrant works to visit medical facilities and perform health behaviors appropriately. Therefore, diverse strategies should be developed by nurses to enhance the health literacy level of migrant workers.
Health Behavior
;
Health Literacy
;
Health Status
;
Humans
;
Korea
;
Length of Stay
;
Patient Education as Topic
;
Transients and Migrants
8.A Case of Anterior Cervical Hypertrichosis.
Jung Eun LEE ; Mi Jung LEE ; Sang Ju LEE ; Seung Hun LEE
Annals of Dermatology 2004;16(3):132-133
No abstract available.
Hypertrichosis*
9.Evaluation of Enzyme Immunoassay for the Diagnosis of pulmonary Tuberculosis.
Jin Hee PARK ; Jung Won HUH ; Mi Ae LEE
Korean Journal of Clinical Microbiology 2000;3(1):48-52
BACKGROUND: The diagnosis of tuberculosis has been based on the detection of tubercle bacilli by acid-fast stain of smear or cultures, and recently the serologic diagnosis of tuberculosis has been provided a means of sensitive and specific detection of Mycobacterium tuberculosis. We evaluated the utility of enzyme immunoassay using determiner Tuberculosis Glicolipids(TBGL) antibody kit(Kyowa Medex Co. Ltd, Japan) to detect anti-TBGL antibody for diagnosis of pulmonary tuberculosis. METHODS: Anti-TBGL antibody assay was performed to the form 44 patients with active pulmonary tuberculosis(17 patients with smear positive, 7 patients with only culture positive, 20 patients with clinically active tuberculosis) and 80 controls (30 healthy controls, 24 patients with non-tuberculous respiratory diseases, 26 patients with inactive tuberculosis). We compared the sensitivity and specificity of anti-TBGL antibody with culture and AFB stain. RESULTS: Anti-TBGL antibodies were detected in 16 of 17(94%) smear positive patients, 4 of 7 patients with only culture positive and 16 of 20(80%) smear negative patients who had been clinically diagnosed as active pulmonary tuberculosis. Nine(35%) out of 26 patients with inactive tuberculosis, one(4%) out of 24 patients with non-tuberculous respiratory diseases and no one of healthy control had a positive antibody response. Overall sensitivity, specificity of the anti-TBGL antibody assay were 82%, 88%, respectively and sensitivities and specificities of culture and AFB smear 64%, 97%, and 49%, 100%, respectively. Anti-TBGL antibody titers in patients with active tuberculosis were significantly higher than control grup(P<0.05). Conclusions : The anti-TBGL antibody assay was sensitive, rapid and convenient. This assay will be useful as a tool for the diagnosis of tuberculosis in combination with other conventional methods.
Antibodies
;
Antibody Formation
;
Diagnosis*
;
Humans
;
Immunoenzyme Techniques*
;
Mycobacterium tuberculosis
;
Sensitivity and Specificity
;
Tuberculosis
;
Tuberculosis, Pulmonary*
10.Clinical Course and Predictable Factors for Remission of Hashimoto' Thyroiditis in Children and Adolescents.
Keun Hye LEE ; Mi Jung KIM ; Heon Seok HAN
Journal of Korean Society of Pediatric Endocrinology 2004;9(1):34-41
PURPOSE:The natural course of Hashimoto' thyroiditis (HT) is so dynamic that the disease progresses to overt hypothyroid or spontaneous recovery. The authors reviewed the clinical course of this disease and analysed the possible predicting factors regarding remission. METHODS:Thirty nine patients with HT (38 girls and 1 boy) were studied retrospectively. Of these patients, 30 were followed for more than 2 years. The possible remission factors were analyzed at initial diagnosis and during follow-up period. RESULTS:The mean age at the diagnosis was 11.8+/-.1 years. Initial thyroid function was euthyroid in 38.5%, compensated hypothyroid in 35.9%, overt hypothyroid in 23.1%, and hyperthyroid in 2.6% of patients. Antithyroglobulin antibody (ATA) was positive in 94.7%, and antimicrosomal antibody (AMA) was positive in 74.4%. The overall remission rate was 53.3% during the follow-up period (51+/-7 months). Initial goiter size, thyroid function status, and autoantibody titer had no relation to the remission rate statistically. Follow-up autoantibody titers in remission group were marginally lower than those in nonremission group (P<0.1), and follow-up AMA titer was significantly higher than initial titers in nonremission group (P<0.05). CONCLUSION: We could not find any predictable remission factors from the initial clinical and autoantibody status. But, during follow-up period, patients with lower autoantibody titers showed slight higher remission, and those with increasing AMA titer showed less remission. Above results suggest that we should monitor antithyroid antibody titer as well as thyroid function regularly.
Adolescent*
;
Child*
;
Diagnosis
;
Female
;
Follow-Up Studies
;
Goiter
;
Humans
;
Retrospective Studies
;
Thyroid Gland*
;
Thyroiditis*