No abstract available.
Kidney Transplantation*

Fibro-osseous pseudotumor is an extremely rare benign lesion which is fast-growing and painful. It is often misdiagnosed as a malignancy, but it is a noninvasive entity and can be cured by simple resection. We report a case of fibro-osseous pseudotumor of the distal phalanx of great toe in 20-year-old female patient who present with painful mass.
Female ; Humans ; Toes ; Young Adult

A secondary cleft lip nasal deformity can be corrected by many procedures including central lip tissue transfer, forked flap, nasal floor and alar base advancement, nasal skin flaps and composite graft. These procedures have been applied for many years, but each one has some conspicuous residual problems. We propose triple V-Y advancement flaps, which we have performed on 13 secondary cleft lip and nasal deformity patients over the past 6 years. The W-shaped triple reverse V-shaped incision easily exposed the alar cartilages. We made the advancement and rotation of the nasal skin flap to lengthen the columella and project the nasal tip. Postoperatively, the columella length and nasolabial angle were found to be increased by an average of 3.7 mm and 42 degrees, respectively. In lateral view, a relatively natural nasal line was achieved. The scar in the nasal tip posed few problems. This procedure should be useful for the correction of the secondary cleft lip nasal deformity.
Cartilage ; Cicatrix ; Cleft Lip* ; Congenital Abnormalities* ; Humans ; Lip ; Skin ; Transplants

No abstract available.
Humans ; Pregnancy, Twin* ; Twins*

Amyotropic lateral sclerosis(ALS) is a progressive degenerative illness of unknown cause ; we present its characteristic brain magnetic resonance(MR) findings in one patient. A 58-year-old woman who for two years had been suffering from progressive motor weakness and dysarthria was admitted to our hospital. Physical examination and laboratory findings showed a pattern of both upper and lower motor neuron disease such as decreased motor power(Grade III), tongue atropy, increased deep tendon reflex, a pattern of lower motor neuron disease, as seen on electromyogram, and a pattern of sparing sensory nervous system, extraocular muscle movement bladder, and bowel function. On axial brain MR proton-density and T2-weighted images, small round areas of high signal intensity were seen bilaterally in the posterior limb of the internal capsule ; these corresponded to the corticospinal tract. Additionally, bilateral, subtle linear low signal intensity in the precentral gyrus was noted on T2-weighted imaging. On the basis of the findings of clinical and laboratory examination, and of typical MR imaging findings, ALS was diagnosed.
Brain* ; Dysarthria ; Extremities ; Female ; Humans ; Internal Capsule ; Magnetic Resonance Imaging* ; Middle Aged ; Motor Neuron Disease ; Nervous System ; Physical Examination ; Pyramidal Tracts ; Reflex, Stretch ; Tongue ; Urinary Bladder

The free flaps have been used for reconstruction of the head and neck because of their superior results comparing with other types of flaps. Among them, radial forearm free flap has many advantages, its thinness, pliablilty, long vascular pedicle, large sensory flap, and compound flap including tendons and bone. We report 28 cases of head and neck reconstruction with radial forearm free flap between March 1991 and March 1997. Patient's age ranged from 21 to 76 years(mean 50.5 years). There were 23 men and 5 women. Mean follow-up period was 14 months. The most common cause was malignant tumor of the head and neck, especially squamous cell carcinomas(18 cases). We used this flap to reconstruct the oral cavity in 13 cases, the hypopharyngoesophagus in 6 cases, external surface of the head and neck in 7 cases, and the orbit in 2 cases. All of these flaps survived without complication. Two cases of fistula developed, in which forearm flaps were used for tongue and hypopharyngoesophageal reconstruction, and they were treated with conservative manners. Partial losses of skin graft at donor site of the forearm developed in 3 cases. They healed with split-thickness skin graft or local flap. The function of reconstructed upper aerodigestive tract and eye socket was good. The cosmetic result was not good in cases of reconstruction for external surface of the face with this flap, but it was better than other free flaps. So, we concluded the radial forearm free flap is available for reconstruction of the head and neck.
Female ; Fistula ; Follow-Up Studies ; Forearm* ; Free Tissue Flaps* ; Head* ; Humans ; Male ; Mouth ; Neck* ; Orbit ; Skin ; Tendons ; Thinness ; Tissue Donors ; Tongue ; Transplants

To investigate the protective effect of hyaluronic acid on the corneal endothelial damage induced by perfusion with hydrogen peroxide, rabbit corneas were mounted in the in vitro dual-chambered specular microscope and perfused with glutathione-bicarbonate-ringer(GBR) solution for one hour, and test agents for additional two hours. Test agents were hydrogen acid(0.01%). and chondroitin sulfate(0.04%). Corneal thickness was measured every 15 minutes during the perfusion and a corneal swelling rate was calculated by linear regression analysis. At the end of perfusion, corneas were fixed for transmission electron microscopy(TEM). Hydrogen peroxide(0.5mM) caused marked corneal swelling white 0.25mM did not(65.95+/-8.03 vs. 6.69+/-2.58micrometer/hr). Healon prevented the H2O2 induced corneal swelling(15.85+/-2.99micrometer/hr) and maintained the endothelial ultrastructures. Viscoat enabled the corneas to deswell(-35.90+/-18.04micrometer/hr). Hyaluronic acid(0.01%) and catalase(15000U) also prevented corneal swelling induced by hydrogen peroxide(9.52+/-3.61, 4.61+/-0.99micrometer/hr respectively), and maintained the endothelial ultrastructure, however 0.04% chondroitin sulfate showed marked corneal swelling(71.73+/-2.12micrometer/hr). The results of this study showed that Healon and Viscoat containing hyaluronic acid could protect corneal endothelial cells from hydrogen peroxide.
Catalase ; Chondroitin ; Chondroitin Sulfates ; Cornea ; Endothelial Cells ; Endothelium, Corneal ; Hyaluronic Acid* ; Hydrogen Peroxide* ; Hydrogen* ; Linear Models ; Perfusion

No abstract available.
Female ; Ovulation*

No abstract available.

OBJECTIVES: The purpose of this study was to aid in the prediction of tumor cell tolerance to radiotherapy and/or chemotherapy. MATERIALS AND METHODS: Human epidermoid carcinoma A-431 cell line were irradiated by 2, 4, 6, 8, 10Gy at a dose rate of 210cGy/min using 60Co Irradiator ALDORADO 8 and then were exposed to bleomycin or cisplatin at concentration of 2mug/mul for 1 hour. The viable cells were determined for each radiation dose and/or each drug at the 4th day and cell surviving curves were obtained using semiautomated MTT assay. RESULTS: The surviving fraction after irradiation of 2Gy was 0.99, and there was not significant difference of surviving fraction in comparison with the control group on A-431 cell line(p>0.05). But there were significant differences of surviving fractions at doses of 4, 6, 8, 10Gy in comparison with the control group(p<0.05). The cytotoxicity of bleomycin or cisplatin was significantly different in comparison with the control group on A-431 cell line (p<0.05). And the cytotoxicity of cisplatin was greater than that of bleomycin on A-431 cell line (p<0.05). There were significant differences of surviving fractions after irradiation of 2, 4, 6, 8, 10Gy with bleomycin or cisplatin in comparison with each group of irradiation only on A-431 cell line(p<0.05). There were significant differences of surviving fractions between the groups of irradiation with bleomycin and cisplatin at doses of 2, 4Gy(p<0.05), but there were not significant differences of surviving fractions at doses of 6, 8, 10Gy on A-431 cell line (p>0.05).
Bleomycin ; Carcinoma, Squamous Cell ; Cell Line* ; Cisplatin ; Drug Therapy ; Humans ; Radiation Tolerance* ; Radiotherapy