1.Application of computer-assisted instruction for Case-based teaching in medical imaging
Jianzhong ZHU ; Jian QIN ; Junjie LIU
Chinese Journal of Medical Education Research 2003;0(02):-
Objective A study was performed to better define the teaching outcome of computers in teaching medical imaging. Methods 150 4rd-year students were randomly assigned to four groups and experimental group exposed to 20 radiology cases as well as to a voluntary weekly radiology lecture. Group A used computer-based cases with interactive elements; group B used computer-based cases without interactive elements; group C used paper-based cases with interactive elements; and group D was not exposed to the cases and served as a control group. Results On a multiple-choice question test,groups A,B,and C showed significant improvemen(t+10.6%,+15.7%,+13.5%,respectively),whereas group D did not(+2.7%). On an image interpretation test,group A and group B showed the most improvement (+15.8%,P
2.Effect of Xuezhikang on Serum MCP-1 Level and Endothelial Function in Patients with Chronic Heart Failure
China Pharmacy 2007;0(27):-
OBJECTIVE:To observe the effect of Xuezhikang on serum MCP-1 and endothelial function of brachial artery in patients with chronic heart failure but with normal cholesterol level. METHODS:Patients with chronic heart failure (NYHAⅡ-Ⅳ) were randomly allocated into two groups(n=24 each). Both groups received routine treatment in accordance with the guide of CHF treatment,additionally,the treatment group received Xuezhikang 0.6 g bid for 8 weeks. Serum levels of MCP-1 before and after treatment were measured by ELISA and endothelial function of brachial artery was detected by ultrasonography. RESULTS:In Xuezhikang-treated group compared with the control group,serum level of MCP-1 decreased significantly(P
3.Fall risk assessment and relative interventions in the elderly: A latest advances
Jian ZHOU ; Bo LIU ; Mingzhao QIN
Chinese Journal of Geriatrics 2021;40(3):388-392
Fall is one of major causes of disability, reduced mobility, shortness of life span and increased medical costs in the elderly.There are multiple risk factors for falls in the elderly, but they can be preventable and controlled.This article reviews the evidences regarding the clinical effectiveness, practicalness and security of these fall risk assessment methods and measures of interventions by evidence-based medicine in the elderly and analyzes their research directions.
4.Prevalence of osteoporosis, osteopenia, fall and brittle fracture and their associated factors in men aged 80 years and over
Jian ZHOU ; Mingzhao QIN ; Qian LIU ; Jinping LIU
Chinese Journal of Geriatrics 2017;36(8):868-871
Objective To investigate the prevalence of osteoporosis,osteopenia,fall and brittle fracture and their associated factors in men aged 80 years and over.Methods In a prospective study,184 study subjects with good self-care ability aged 80 years and over were enrolled.The questionnaire included living habits,falls,comorbidities,related symptoms and medicines.The bone mineral density,hand-grip strength,gait speed,timed up and go test(TUG),chair rising test(CRT),bone turnover markers and related hormones were measured.Binary Logistic regression model was used to analyze associated factors for osteoporosis,osteopenia,fall and brittle fracture.Results The prevalence of osteoporosis (OP)and osteopenia(OPA) were 12.5 % (23/184) and 45.1% (83/184) respectively in this study.The height,weight and body mass index were lower,and serum levels of procollagen type 1 N terminal propeptide(P1NP)and C-telopeptides of type 1 collagen(s-CTx)were higher in osteoporosis group than in normal bone mass(NBM) group(P<0.05,P<0.01).The estradiol levels were lower in OP and OPA group than in NBM group(P< 0.05).The risk factors for OP and OPA included smoking(OR =3.607,P<0.05),decreased body weight (OR=0.823,P < 0.05) and elevated S-CTx level (OR =12.427,P < 0.01).55.4% (102/184) of study subjects had fall history after 80-year old.The prevalence of fragile fracture was 17.4% (4/23),18.1 % (15/ 83)and 3.8%(3/78)in OP,OPA and NBM groups respectively,with total prevalence of 12.0% (22/184).The risk factors for fragile fracture were a decreased total hip BMD(OR 0.017,P<0.05)and fall history after 80-year-old(OR 13.126,P < 0.05).Conclusions Based on associated factors of osteoporosis,osteopenia,falls and fragile fracture in male aged 80 years and over,the primary and secondary prevention of osteoporosis may need a comprehensive geriatric intervention including lifestyle adjustment,fall prevention and pharmacologic treatments.
5.Acute tin poisoning caused by water pollution: report of 3 cases.
Li SUN ; Jian-ning LIU ; Guo-qin XIA
Chinese Journal of Industrial Hygiene and Occupational Diseases 2012;30(11):871-872
Adult
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Arsenic Poisoning
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etiology
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Female
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Humans
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Male
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Middle Aged
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Organotin Compounds
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poisoning
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Water Pollution
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Young Adult
6.Preliminary discussion of program and evaluation system for standardized training residents in the intensive care unit
Ning LIU ; Danjiang DONG ; Jian TANG ; Qin GU
Chinese Journal of Medical Education Research 2015;14(6):623-626
Critical care medicine has the characteristics of complex,a wide range of knowledge,and interdisciplinary,so standardized training is difficult.Intensive Care Unit explored a standardized training mode and evaluation system suitable for standardized training residents in the Intensive Care Unit,including generalizing training target,developing step by step teaching plans,establishment of entrance education,basic theory,basic skills,scientific thinking and doctor-patient communication training with diversity of teaching methods,including lecture-based learning,problem-based and casebased learning,implement the flexible and strict evaluation system.
7.Outbreaks of norovirus infections in Zhejiang province during 2004-2014
Shuwen QIN ; Chengliang CHAI ; Jian CAI ; Ziping MIAO ; Shelan LIU
Chinese Journal of Clinical Infectious Diseases 2014;7(4):324-327
Objective To review the epidemiologic features of norovirus infection outbreaks in Zhejiang province during 2004-2014.Methods Epidemiological data of norovirus infection outbreaks in Zhejiang province from January 2004 to February 2014 were collected from the Emergency Public Reporting System in Zhejiang Provincial CDC.The distribution of time,area,population,route of transmission and genotype of norovirus were analyzed.Results There were 16 outbreaks of norovirus infections with 2 037 cases during 2004-2014 in Zhejiang province.Eleven outbreaks occurred during February and April,and 13 outbreaks occurred in schools.The outbreaks in schools mainly involved students aged 15-20 years,while other outbreaks took place mainly in the young and middle-aged population.The sex ratio of male to female was 1.05 ∶ 1.Among 16 outbreaks,10 were induced by norovirus G Ⅱ infections,3 were induced by norovirus G Ⅰ infections and 3 were induced by norovirus G Ⅰ and G Ⅱ infections.Fourteen outbreaks were caused by water pollution.Conclusion Outbreak of norovirus infection usually occurs in schools during winter and spring in Zhejiang province,and the epidemic of disease is mainly associated with polluted water.
8.Research progress of the non-contact monitoring of heart, lung and brain
Wenjun LIU ; Jian SUN ; Gui JIN ; Jinbao WANG ; Mingxin QIN
International Journal of Biomedical Engineering 2013;(1):30-33,55
In recent years,the research of non-contact biomedical monitoring has continuous development and progress.This review gives an overview of the research status of heart,lung and brain non-contact monitoring methods.The correlation techniques of capacitance electrocardiogram,magnetic induction,radar non-contact monitoring of heart and lung,and non-contact monitoring of brain are analyzed comprehensively.Capacitance electrocardiogram monitors the heart and lung activities useing effect of change in capacitance between the electrodes.Magnetic induction monitors the heart and lung activities useing the Maxwell principle,while radar monitoring the heart and lung activities uses the Doppler effects.Non-contact monitoring of brain adopts the magnetic induction tomography imaging technology.Then elaborate related research at home and abroad,and summarize the advantages and disadvantages of these monitoring methods on the basis of the analysis of monitoring principles.Finally foreground that may dominate this area of new equipment for heart,lung and brain non-contact monitoring in the future is expected.
9.Intravitreal bevacizumab (Avastin) treatment of macular edema in branch retinal vein occlusion
Bo, QIN ; Shen-Wen, LIU ; Jian, ZENG ; Xun-Qing, GU
International Eye Science 2009;09(3):414-416
AIM:To report the safty and efficiency of intravitreal injection of bevacizumab (Avastin) in patients with macular edema (ME) due to branch retinal vein occlusion (BRVO).METHODS: A consecutive series of patients with ME due to BRVO who were treated with intravitreal bevacizumab injection (2.5g/0.1L) were retrospectively studied. Patients underwent complete ophthalmoscopic examination, including Snellen visual acuity testing, optical coherence tomography (OCT) imaging, and/or flurescence angiographic testing at baseline and follow-up visits.RESULTS: There were 32 eyes of 32 consecutive patients who received at least one intravitreal bevacizumab injections (range from 1 to 3). The mean length of follow-up was 4.7 (range from 3 to 8) months. The mean visual acuity improved from 20/200- at baseline to 20/100- at 1 month and 20/100+ at 3 months and last follow-up (P<0.01). The mean central 1mm macular thickness was 483μm at baseline and decreased to 275, 314,and 301μm at 1 month,3 months, and last follow-up (P<0.01)respectively.No adverse side effects were observed following injections in any eyes.CONCLUSION: Intravitreal bevacizumab (Avastin) showed a marked decrease in ME secondary to BRVO, improvement in visual acuity and lack of adverse side effects.
10.An analysis of monitoring results on iodine deficiency disorders in Baoji City of Shaanxi Province from 2009 to 2011
Mei, LIU ; Hong-wei, ZHU ; Yan-qin, GAO ; Jian, GAO
Chinese Journal of Endemiology 2013;(3):293-295
Objective To learn the control status of iodine deficiency disorders in Baoji City of Shaanxi Province.Methods From 2009 to 2011,according to the National Iodized Salt Monitoring Program,the iodized salt was monitored,and thyroid was examined in 12 counties(areas) of Baoji City.According to rural and urban area stratification,60 children aged 8 to 10 were selected in each county(district),and their urine samples were collected for determination of iodine content.In 2011,per capita daily salt intake was surveyed by the three weighing method at children's home whose urine was collected.Chencang Area,Fufeng County and Taibai County,representatives of Baoji City different geomorphic features were selected for investigation of water iodine,and urinary iodine of pregnant and lactating women,and 15 people were selected in each county (district).Results From 2009-2011,in the 12 counties(areas) in Baoji City,the coverage rate of iodized salt was all 100.00%(3468/3468); the qualified rate of iodized salt and the consumption rate of qualified iodized salt were all > 99.00%.Children's goiter rate was 3.41%(87/2548),3.06%(77/2520) and 3.33%(84/2520),and they were all less than that of the national standard (< 5%).Medians of urinary iodine of 8-10 years old children were 368.20,293.80 and 332.50 μg/L,respectively,and the ratios of urine iodine ≥300 μg/L were accounted for 66.42% (797/1200),48.05%(692/1440) and 56.67%(816/1440),respectively.Median urinary iodine of pregnant women was 301.81 μg/L and lactating women was 329.79 μg/L.A total of 1116 households were investigated,the median of per capita daily salt intake was 8.9 g.Eighteen water samples were collected,range of water iodine value were 0.60-10.25 μg/L.Conclusions Iodine nutrition in general population of Baoji City is exceeded the optimum level,and the current iodized salt concentration has some down space,but fully consideration should be taken on iodine needs in different iodine deficiency areas and among different groups of people.