In order to provide some more scientific and practical advice and tactics for acupuncture in prevention of migraine in clinic, a computer-based information search was conducted in MEDLINE database, and the current reports of clinical trials were summarized and a comparison of Western and Chinese research designs was made. The significant role of acupuncture for prevention of migraine has not been applied in wide range in China until the present day. However, it has been paid great attention in Western countries. This situation might be related to the differences of efficacy assessment of acupuncture between China and Western countries; meanwhile, in the past traditional acupuncturists put much stress on the therapeutic approaches for acute attacks of headache but less on prevention. It is necessary for Chinese doctors to learn from research method in the West and emphasize more on acupuncture for preventing migraine and conduct high-level clinical trials as well. The author recommends that Chinese doctors should select acupuncture points mainly according to meridian syndrome differentiation and apply long term intermittent interventions.

This study is to evaluate the HAART pharmacodynamics with dolutegravir as the "anchor" in vitro. A nucleoside reverse transcriptase inhibitors (NRTIs) resistant recombinant virus model (VSVG/HIV-1(RT-D67N,K70R,T215F)) and an integrase inhibitors (INIs) resistant recombinant virus model (VSVG/HIV-1(IN-G140S,QI48H)) were constructed and established. The anti-viral pharmacodynamics was evaluated with drug combinations including two NRTIs along with one INI or one NNRTI. The results showed that the combination with an INI gave a stronger synergism on wild type HIV-1 replication comparing to that with an NNRTI. Comparing the two INIs as the "anchor" for HAART, DTG exhibited an equivalent CI to that of RAL on wild type HIV-1 replication; but a greater synergy than RAL on INI-resistant HIV-1 replication. Besides of the pharmacodynamics results of DTG-based drug combination, the results may contribute to clinical antiviral therapy.
Antiretroviral Therapy, Highly Active ; Cells, Cultured ; Drug Resistance, Viral ; HIV Integrase Inhibitors ; pharmacology ; HIV-1 ; drug effects ; physiology ; Heterocyclic Compounds, 3-Ring ; pharmacology ; Humans ; Virus Replication ; drug effects

Adult ; Coke ; Female ; Humans ; Male ; Middle Aged ; Pyrenes ; analysis ; Urinalysis ; Urine ; chemistry ; Young Adult

Animals ; China ; epidemiology ; Humans ; Schistosomiasis ; epidemiology ; prevention & control

Angioplasty, Balloon, Coronary ; Humans

Aged ; Chondroma ; diagnosis ; Diagnostic Errors ; Humans ; Laryngeal Neoplasms ; diagnosis ; Male ; Tracheal Neoplasms ; diagnosis

Animals ; Environmental Monitoring ; methods ; Geographic Information Systems ; Snails

Hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver.The incidence and mortality rates were ranked the sixth and three respectively in all kinds of tumors.Liver resection and liver transplantation has achieved remarkable curative effect in the treatment of early of HCC,but the recurrence is still an important problem to be solved.In HCC patients,local resection and liver transplantation after 5 years,the recurrence rate wasere 70％ and 35％,respectively.The invasiveness of tumor is different,and the recurrence rate is also different.Microvascular invasion (MVI) as a marker of tumor invasion has been widely used in the diagnosis of HCC.Some scholars believe that MVI imay bes the first step in the liver or systemic metastasis of liver cancer,if we can predicted the MVI before surgery,it will play a positive role in making treatment programs,because in order to reduce the recurrence rate,anatomic resection of and extended resection range is recommended.Advances in magic radiological technology have made made it possible to diagnose MVI before surgery.In this paper,CT,MRI,PET and ultrasound in the diagnosis of MVI would be introduced.

Objective:To participate in the anti-infection regimen adjustment and perform pharmaceutical care for one pneumonia patient after lung transplantation by clinical pharmacist to provide experience for individualized medication. Methods:Clinical pharma-cist adjusted the treatment plan and doses of immunosuppressive agents according to the patient' s conditions. Results: The infection was effectively controlled through optimizing the treatment plan. Conclusion:Pharmaceutical care for patients after lung transplantation performed by clinical pharmacists is helpful to both the recovery of patients and future appropriate drug use.

0.05). Multivariate analysis revealed that risk factors for vascular complications included the difference in radial artery diameter and sheath size; prolonged procedure time and comorbidity of diabetes mellitus. Conclusion Transradial access is a safe and practical alternative approach for intervention procedure. Vascular ultrasonic examination is valuable for selection sheath before invention procedure especially in patients with diabetes mellitus and in assessment vascular complications after the procedure.