1.Two Cases of Sex-linked Ichthyosis Improved by an Oral Aromatic Retinoid (Ro 10 - 9359).
Korean Journal of Dermatology 1982;20(3):431-436
We present the therapeutic effects of an aromatic retinoid (Ro 10-9359) in two cases of sex-linked ichthyosis. Case 1, Uncle of Case 2, was a 24-year-old male who had had dark brown scales on the trunk and upper extremities for 15 years. Case 2 was a 10-year-old boy who had had dirty brown scales on the trunk and lower extremities since 3 years of age. The diagnosis of sex-linked ichthyosis was made by characteristic scales and histopathologic findings. Initially, both patients received an oral aromatic retinoid (Ro 10-9359) with a daily dose of 1.5mg/kg body weight for the first two weeks. Thereafter the drug was tapered gradually to the dose of 0.5mg/kg body weight according to the therapeutic response. There was near complete clearing of the skin lesions in both patients after 10 weeks treatment. Side effects were of mild intensity and included dryness of mouth and nose, chelitis, paronychia and arthralgia of knee joint.
Arthralgia
;
Body Weight
;
Child
;
Diagnosis
;
Humans
;
Ichthyosis*
;
Knee Joint
;
Lower Extremity
;
Male
;
Mouth
;
Nose
;
Paronychia
;
Skin
;
Upper Extremity
;
Weights and Measures
;
Young Adult
2.Aggressive Angiomyxoma of the Scrotum: A case report.
Jong Eun JOO ; Eun Kyoung KIM ; Hong Sun UH
Korean Journal of Pathology 1999;33(1):59-61
Aggressive angiomyxoma is a rare, locally aggressive tumor and occurs exclusively in the pelvic and perineal regions of women. But this tumor can occur in men, and the ratio of man to woman is about 1:6. We report a case of aggressive angiomyxoma of the scrotum in a 75-year-old man. The resected mass measured 23 21 10 cm and weighed 1,150 g, and was covered with thick but intact scrotal skin. The cut surface of the mass showed pale yellow to grayish white loose and edematous fibrous tissue with focal cystic degeneration. Microscopically, the mass was composed of loosely arranged bland-looking spindle or stellate cells and variable sized blood vessels with thickened and hyalinized wall. The spindle cells were strong positive for vimentin, focal, weak positive for desmin and smooth muscle actin but negative for S-100 protein. The spindle cells were also positive for estrogen and progesterone receptors.
Actins
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Aged
;
Blood Vessels
;
Desmin
;
Estrogens
;
Female
;
Humans
;
Hyalin
;
Male
;
Muscle, Smooth
;
Myxoma*
;
Receptors, Progesterone
;
S100 Proteins
;
Scrotum*
;
Skin
;
Vimentin
3.A Study on Photopatch Test in Photodermatoses.
Joo Eun JANG ; Jeong Hee HAHM ; Hong Il KOOK
Korean Journal of Dermatology 1983;21(5):531-536
It is believed that the photopatch test is a valuable screening procedure for the determination of responsible antigenic substances in photoallergic contact dermatitis. But the technigues used for this procedure are cumbersome and require expensive equipment. In the present study, we adapted an easy and inexpensive photopatch test met- hod to our need. We report the results of this test method which was performed. in 21 patients with photodermatitis and 9 patients with polymorphic light eruption. 1. The UVB sensitivity determined by minimal erytherna dose (mean+-standard deviation) was I1618mW sec/cm in photodermatitis group, 108+ROmW sec/cm in polymorphic light eruption group and 126-+32mW-sec/cm in control group. But there was no significant difference among them (p>0. 05). 2. The reaction to UVA were negative in all groups. R. The photopatch test using IO potential photosensitizers revealed 12 positive responses in 9 patients; including 7 patients in photodermatitis group and 2 patients in polymorphic light eruption group. And the number of positive photopatch responses obtaied with each photosensitizer in RO patients with photodermatoses was 5 in chlorhexidine, 2 in paraaminobenzoic acid, musk ambrette and bithionol and 1 in chlorpromazine, respectively.
Bithionol
;
Chlorhexidine
;
Chlorpromazine
;
Dermatitis, Photoallergic
;
Humans
;
Mass Screening
;
Photosensitivity Disorders
;
Photosensitizing Agents
4.The changes of arterial and end-tidal carbon dioxide tension by respiratory rate and tidal volume.
Eun Kil RAH ; Hyun Joo OH ; Hong Suk YANG
The Korean Journal of Critical Care Medicine 1993;8(1):27-32
No abstract available.
Carbon Dioxide*
;
Carbon*
;
Respiratory Rate*
;
Tidal Volume*
5.Squamous Cell Carcinoma Arising from Chronic Osteomyelitic Sinus: A Report of Three Cases
Myung Sang MOON ; Han Joo KIM ; Nam Yong CHOI ; Hong Joong KIM ; Eun Joo SEO
The Journal of the Korean Orthopaedic Association 1986;21(1):160-164
The developement of squamous cell carcinoma from the draining sinus of chronic osteomyelitis has long been recognized as a rare and late complication. The mode of developement of carcinoma at the site of chronic osteomyelitis is not well understood. This, however, is chiefly a disease of middle aged men, and tibia is the most common site. There are two types in this carcinoma; superficial and deep types. In the superficial type obvious presence of fungaiing growth makes diagnosis simple and easily confirmed by biopsy. In the deep type the diagnosis is difficult clinically, but the features most frequently described are an increase in pain and discharge with swelling and hemorrhage. Amputation at the adequate level is the treatment of choice. Three cases of the disease involving one left femur, and two left tibiae are reported with review of literature.
Amputation
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Biopsy
;
Carcinoma, Squamous Cell
;
Diagnosis
;
Epithelial Cells
;
Femur
;
Hemorrhage
;
Humans
;
Male
;
Middle Aged
;
Osteomyelitis
;
Tibia
6.A Case of Edward Syndrom.
Youn Hong CHOI ; Hyun Joo CHOI ; Eun Hwa SHIN ; Ju Hong CHA ; Kwang Jeon KIM
Journal of the Korean Pediatric Society 1989;32(3):396-401
No abstract available.
7.Clinical Type and Treatment Response in Patients with Digital Mucous Cyst: A Retrospective Study
Joon Woo JUNG ; Eun Hye HONG ; Eun Joo BAEK ; Eun Joo PARK ; Kwang Joong KIM ; Kwang Ho KIM
Korean Journal of Dermatology 2021;59(10):742-748
Background:
Digital mucous cysts (DMCs) are benign, occurring mainly on the fingers but rarely on the toes.Although the exact cause of DMC has not been identified, it is classified into two different types based on its pathogenesis and location. Surgical and nonsurgical procedures, including aspiration, sclerotherapy, steroid injection, cryotherapy, and CO 2 laser, can be used to treat DMC.
Objective:
This study aimed to compare treatment response based on DMC type and evaluate its efficacy in surgical and nonsurgical (sclerotherapy) treatments.
Methods:
We retrospectively reviewed the electronic medical records of patients with DMC who visited our dermatology department between January 2010 and November 2020.
Results:
This study enrolled 39 patients having a mean age of 59.2 years. The proportion of female patients (21/39, 53.8%) was more than male (18/39, 46.2%). The DMC occurrence was more frequent in the fingers (32/39, 82.1%), especially in the index and middle fingers than in the toes (7/39, 17.9%). In sclerotherapy, DMC in the distal interphalangeal joint (DIPJ) required more treatment than that in the proximal nail fold (PNF) (p<0.05). The number of treatments using sclerotherapy was higher compared to that of surgical treatments (p<0.05).
Conclusion
The DIPJ type of DMC patients was more difficult to treat using sclerotherapy than the PNF type.Moreover, surgical treatment has a better response than sclerotherapy.
8.Usefulness of Ultrasonography in the Diagnosis of Peptic Ulcer Disease in Children.
Eun Joo LEE ; Yeoun Joo LEE ; Jae Hong PARK
Pediatric Gastroenterology, Hepatology & Nutrition 2019;22(1):57-62
PURPOSE: This study was performed to assess the clinical usefulness of transabdominal ultrasonography (TUS) in detecting peptic ulcer disease (PUD) in children. METHODS: Twenty-four patients (19 boys, 5 girls; mean age, 10.6±4.5 years [range, 3.0–17.9 years]) who were admitted to the hospital for acute abdomen or gastrointestinal bleeding and diagnosed with PUD by endoscopy and who underwent TUS were included. Clinical data were retrospectively collected by reviewing patient medical records. Gastric ulcer (GU) was suspected when the gastric wall exceeded 8 mm in thickness and had lost its five-layer structure on TUS. Duodenal ulcer (DU) was suspected if the duodenal wall thickness exceeded 5 mm. RESULTS: Sensitivity of TUS in diagnosing PUD was 66.7% for GU and 38.9% for DU. Mean age and body weight of the 11 patients suspected with PUD on TUS were 10.9±4.4 years and 38.1±17.2 kg, respectively. For 13 patients without suspected PUD, they were 12.1±4.1 years and 39.6±17.0 kg, respectively. There was a significant difference in height, weight, and body mass index between patients who were suspected to have PUD and those who were not suspected on TUS (p=0.014, 0.008, and 0.005, respectively). A significant difference in the sensitivity of TUS in diagnosing PUD was found between patients under 30 kg and those over 30 kg (88.9% and 20.0%, respectively; p=0.003). CONCLUSION: TUS investigation of the stomach and duodenum is an efficient method for PUD detection in children with low body weight. TUS can be used in preliminary diagnostic work-up before further invasive tests.
Abdomen, Acute
;
Body Mass Index
;
Body Weight
;
Child*
;
Diagnosis*
;
Duodenal Ulcer
;
Duodenum
;
Endoscopy
;
Female
;
Hemorrhage
;
Humans
;
Medical Records
;
Methods
;
Peptic Ulcer*
;
Retrospective Studies
;
Stomach
;
Stomach Ulcer
;
Ultrasonography*
9.Effect of Calcium Intake and Health Status on Blood Lipids in Middle-aged Women.
Soon Myung HONG ; Yeong Eun SEO ; Hyun Joo KIM
Journal of the Korean Dietetic Association 2002;8(3):250-259
The purpose of this study was to confirm that calcium intake and healthy status play a role in reducing the risk of cardiovascular disease, to assure that calcium intake and regular exercise are important in reducing serum lipid levels in middle-aged women. Daily nutrient intakes were analyzed by convenient method. Anthropometric measurement such as body weight and height and blood pressure were measured. The subjects divided into two groups : women in group I under 50 years of age(< or = 49 yr group) and those in group II 50 years up(> or = 50 yr group). Average ages of group I and II were 43.87 and 53.46 years. The nutrients intake of subjects were higher than Korean recommended dietary allowances(KRDA) except calorie, iron, calcium, vitamin B1. They showed significant difference each other in vitamin B2(p<0.05), calcium(p<0.01) intake. Mean daily calcium intake was 540.88mg in < or = 49 yr group and 519.50mg in > or = 50 yr group. The levels of serum cholesterol, triglyceride, blood pressure, Atherogenic Index(AI), LDL/HDL and Cardiac Index(CI) were increased with age. The triglyceride and total cholesterol concentrations and LDL/HDL in > or = 50 yr group were significantly higher than those of < or = 49 yr group. There was a highly significantly positive correlation between age and triglyceride, total cholesterol and Atherogenic Index(AI). Triglyceride, total cholesterol, LDL-cholesterol concentration and Atherogenic Index(AI) were positively correlated with body weight and WHR(waist-hip ratio). Also ther was a significantly negative correlation between exercise and Cardiac Index(CI). Also a significantly negative correlation was found between Ca intake and LDL-cholesterol. Exercise and Cardiac Index(CI) also had a significantly negative relation. The results suggest that increased habitual physical activity and calcium intake should be recommended as a way of decreasing blood lipids and blood pressure in middle-aged women.
Blood Pressure
;
Body Weight
;
Calcium*
;
Cardiovascular Diseases
;
Cholesterol
;
Female
;
Humans
;
Iron
;
Motor Activity
;
Thiamine
;
Triglycerides
;
Vitamins
10.Emphysematous Pyelonephritis in Diabetic Nephropathy A report of two cases.
Jae Ho HAN ; Lucia KIM ; Sung Eun KIM ; Soon Won HONG ; Hyeon Joo JEONG
Korean Journal of Pathology 1999;33(5):367-370
Diabetic nephropathy is characterized by one or a combination of the following lesions: (1) glomerular involvement with three distinctive patterns: diffuse glomerulosclerosis, nodular glomerulosclerosis, and exudative lesions; (2) arteriolo sclerosis; (3) urinary tract bacterial infection with pyelonephritis and sometimes emphysematous pyelonephritis. Emphysematous pyelonephritis is an uncommon life-threatening and acute suppurative infection of the kidney, and usually occurs in diabetic female patients. It is characterized by the production of intraparenchymal gas. Glucose fermentation has been considered the main cause of the gas formation. We presented two illustrative nephrectomy cases of emphysematous pyelonephritis in addition to the typical pathologic features of diabetic nephropathy.
Bacterial Infections
;
Diabetic Nephropathies*
;
Female
;
Fermentation
;
Glucose
;
Humans
;
Kidney
;
Nephrectomy
;
Pyelonephritis*
;
Sclerosis
;
Urinary Tract