Objective: To evaluate the therapeutic efficacy of acupuncture plus Chinese medicinal fumigation and washing in treating edema of the affected limb in post-stroke hemiplegia. ＜br> Methods: Two hundred patients with edema of the stroke-affected limb from our hospital were randomized into two groups according to their visiting sequence. In the observation group, 100 subjects were intervened by acupuncture plus Chinese medicinal fumigation and washing in addition to oral administration of diuretics, while the other 100 subjects in the control group were only given diuretics. The therapeutic efficacy was evaluated after successive 2-week treatments. ＜br> Results: The total effective rate was 90.0% in the observation group, significantly higher than 66.0% in the control group, indicating that there was a significant difference in comparing the overall therapeutic effect (P＜0.01). ＜br> Conclusion: Acupuncture plus Chinese medicinal fumigation and washing in addition to oral administration of diuretics is effective in treating edema of the affected limb in post-stroke hemiplegia.

Objective:To investigate the expression and the effects of CD40/CD40L in lung tissue of rabbits with hemorrhagic shock.Methods:18 healthy rabbits were randomly divided into control group(group A),hemorrhagic shock 1 hour group(group B) and hemorrhagic shock 2 hours group(group C),with 6 rabbits in each group.Except the rabbits in the control group,rest rabbits were made into hemorrhagic shock models with lung injury according to Wiggers modified method.TNF-?、IL-10 in plasma were measured by ELISA.Expressions of CD40 and CD40L in lung tissue were measured by immunohistohemistry.Water quantity and pathological change in the lung were observed.Results:The lung of group B and C displayed obvious injury,water quantity increased(P

OBJECTIVE To learn about the state of disinfecting quality and its impact factors of our hospital in recent 10 years.METHODS According to GB15982-1995 and GB15981-1995 the sampling and surveillance were carried out to the objects concerned for disinfecting in the hospital.RESULTS It showed ascent trend in its entirety for the qualified rate of sample surveillance(70.53-96.34%).The qualified rates of applying disinfecting liquid,medical treatment necessities and pressure steam sterilizer were also higher in the surveillance each year.CONCLUSIONS The lows and regulations correlated with disinfection and operating technological specification have become more and more perfect and flawless,supervision and management also have been intervened and strengthened,and the level of the consciousness and knowledge of disinfection among the staff have had elevation,all these have elevated the disinfection job of the hospital in quality.

Diabetic retinopathy (DR) is a common complication of eye in diabetics and is one of the major causes of blindness in adults.The current treatments of DR include surgery and laser therapy,but this does not fundamentally cure DR.Recent studies have found that mesenchymal stem cells (MSCs) for cell therapy to DR have a wide range of applications.MSCs have regenerative potential and play a role in the repairment of the retina,but the survival and homing ability of MSCs are poor after transplantation,which reduces the therapeutic efficiency of MSCs.Statins have a variety of beneficial effects independent of lipid regulation,which can promote the proliferation of MSCs and inhibit the apoptosis of MSCs.This paper reviewed the application and mechanism of MSCs combined with statins in the treatment of DR.

Microbial secondary metabolites are one of the major sources of anti-bacterial, anti-fungal, antitumor, anti-virus and immunosuppressive agents for clinical use. Present challenges in microbial pharmaceutical development are the discovery of novel secondary metabolites with significant biological activities, improving the fermentation titers of industrial microbial strains, and production of natural product drugs by re-establishing their biosynthetic pathways in suitable microbial hosts. Synthetic biology, which is developed from systematic biology and metabolic engineering, provides a significant driving force for microbial pharmaceutical development. The review describes the major applications of synthetic biology in novel microbial secondary metabolite discovery, improved production of known secondary metabolites and the production of some natural drugs in genetically modified or reconstructed model microorganisms.

Atlanto-axial complex is the most important functional unit of the cervical spine.Atlanto-axial instability or dislocation,one of the most serious pathologies in spinal surgery,is often managed by posterior atlantoaxial fixation and fusion.Several posterior fixation techniques have been used to stabilize the atlanto-axial complex,including wire/cable-bone fixation,Halifax clamps,transarticular screw fixation,screw-plate fixation and screw-rod fixation.For atlanto-axial dislocation that cannot be reduced with skull traction before operation,intraoperative reduction is often needed.Current intraoperative reduction techniques can be classified into transoropharyngeal surgical release followed by posterior reduction and fixation,transoropharyngeal reduction and fixation,and posterior reduction and fixation using screw-rod system according to approaches.Furthermore,posterior reduction can be performed using elevating-pull,leverages,and cantilever techniques.This study reviews the intraoperative reduction and fixation techniques mentioned above.

BACKGROUND:Brain-derived neurotrophic factor has been detected in bone and tooth, and its role in development and metabolism of bone and tooth tissue as wel as its clinical application has become a hot spot. OBJECTIVE: To summarize and analyze the effect and mechanism of brain-derived neurotrophic factor in development and metabolism of bone and tooth tissues. METHODS: Papers addressing the effect of brain-derived neurotrophic factor in bone and tooth tissue were retrieved by computer in Wanfang and PubMed databases with the key words of “brain-derived neurotrophic factor, TrkB, p75NTR, signaling, bone, tooth, osteoblasts, osteoclasts” in Chinese and English, respectively. A total of 53 papers were included for review. RESULTS AND CONCLUSION:Brain-derived neurotrophic factor can be detected in various tissuesin vivo, and can regulate cel survival and apoptosis through binding its two receptors. Brain-derived neurotrophic factor in bone and tooth tissue can bind to target cels, induce or inhibit cel proliferation and differentiation, indicating that brain-derived neurotrophic factor is closely linked to bone and tooth tissue, and may play a role in growth and reconstruction of bone and tooth. Its mechanism of action is mainly through binding to TrkB receptor, to activate downstream pathways and affect differentiation and proliferation of mesenchymal stem cels, osteoblasts, chondrocytes, and periodontal ligament cels. Interaction between p75NTR receptor and TrkB receptor may be one of the factors affecting cel differentiation or proliferation.

0.05).CONCLUSION:Results of study shows there is no significant difference between the therapy of 131I combined with ATD and 131I alone.

Objective To present our experience with the management of symptomatic ureteral calculi during pregnancy and to compare the effi?cacy of two treatments:double?J stent insertion and ureteroscopy. Methods In a retrospective study between January 2007 and January 2015,38 pregnant women were treated for symptomatic ureteral calculi in our hospital. The patients were divided into two groups based on whether they re?ceived double?J stent insertion(n=21)or ureteroscopic lithotripsy(n=17). We collected and compared the patients 'characteristics and treat?ment outcomes,such as success ratio,rate of complications,surgical time,medical costs,and hospitalization time. Results In the double?J group, the insertion of a double?J stent was possible for 17 of 21 patients(success rate,81.0%). In the ureteroscopy group,15 of 17 patients had complete calculi fragmentation(success rate,88.2%). Complications in the double?J stent retention group were slightly higher than in the ureteroscopic litho?tripsy group. The medical costs and hospitalization time required to perform ureteroscopic lithotripsy were significantly higher compared to double?J stent insertion. Patients in the double?J group contended with stones after delivery. Conclusion Both of double?J stent insertion and ureteroscopic lithotripsy are effective for the treatment of symptomatic ureteral calculi during pregnancy. The success rate of ureteroscopy ,which can directly dis?rupt stones,was higher. However,double?J stent insertion costs less and is simple and convenient. The technique that is chosen to be performed de?pends on the patient's practical situation and personal preference.

The teaching and management of our eight-year program students is relatively new,so we should gradually study and explore the adapted cultivation pattern,learn and accumulate the successful experiences of the high starting point teaching in order to cultivate the qualified medical talents.