1.Investigation in psychological state and it's correlation factors of family members of dderly cancerpatients
Chinese Journal of Practical Nursing 2009;25(24):63-64
Objective To investigate the psychological state and its correlation factors of family members of elderly cancer patients. Methods A total of 76 family members of elderly cancer patients were investigated with questionnaires with Zung's self-rating anxiety scale (SAS) and self-rating depression scale (SDS). Their psychological state and its correlation factors were analyzed. Results Incidence rate of anxiety of elderly cancer patients' family members was 52.63%, and incidence rate of depression was 46.05%. The mean standard score of SAS and SDS of elderly cancer patients' family members were both significantly higher than domestic norm. Difference of family member's gender, ways to pay health care fee, pain degree and disease condition led to different SAS and SDS score. Conclusions Family members of elderly cancer patients possessed different degree of psychological obstacle which related with multiple factors. Medical staff should not only think highly of patients' psychological state, but also their family members'. And meanwhile they should take corresponding strategy to reduce the incidence rate of anxiety and depression state in those family members.
2.The Effects of Diazepam on Vestibular Compensation Following Unilateral Labyrinth injury
Chinese Journal of Trauma 1990;0(03):-
This report presents two cases of unilateral acute labyrinth loss resulted from injury,each showing delay in compensation possibly due to long-term administration of diazepam.The recent literature of the effects of the drugs onyestibular compensation is reviewed.The vestibular"suppressants"property of diazepam delays compensation when used on a long-term basis.However,it might be useful in controlling vege- tative symptoms and thereby possibly facilitate compensation when used on a short- tern basis.
3.The experience of the treatment of prostatic hyperplasia(BPH)with bladder calculus
Chinese Journal of Primary Medicine and Pharmacy 2012;19(2):211-212
Objective To evaluate the clinical effect and safety of ureteroscopic pneumatic lithotripsy combined with transurethral resection of prostate(TURP)for treatment of benign prostatic hyperplasia(BPH)with bladder calculus.Methods 68 patients of BPH with bladder calculus treated by ureteroscopic pneumatic lithotripsy combined with transurethral resection of prostate were reviewed.Results Satisfactory effects were achieved in all these 68 cases without serious complications.Conclusion Ureteroscopic pneumatic lithotripsy combined with TURP is a minimally invasive,safe and effective method in the treatment of BPH and bladder calculus.
4.Research progress of antiemetics in tumor therapy
Cancer Research and Clinic 2008;20(12):859-861
Chemotherapy plays a significant role in cancer therapy,but chemotherapy-induced nausea and vomiting(CINV)common happened and affects patients satisfaction with treatment.With the development ot physiology on emesis,the new antiemetics such as 5-HT3 receptor antagonist(5-HT3RA),Aprepitant and Olanzapine greatly improved the control of CINV,the guidelines for antiemeties were deftned.Research progress of antiemetics was summarized.
5.Fatty acid-binding proteins and the early diagnosis of cardio-cerebrovascular diseases
International Journal of Cerebrovascular Diseases 2010;18(2):128-131
Currently, the commonly used diagnostic markers have the shortcomings of lower sensitivity or specificity in the early diagnosis of cardio-cerebrovascular diseases. Therefore, it needs to use the novel specific biochemical markers for the early diagnosis arid treatment, so as to decrease the high mortality and disability caused by cardio-cerebrovascular events. Fatty acid-binding proteins (FABPs) are a family of low-molecular-weight intracellular lipid-binding proteins. They are divided into 9 different subtypes, including the liver-, intestinal-, heart-, brain-, adipocyte-, skin-, ileal-, myelin-, and testis-subtype. Their primary function is to transport long-chain fatty acids into the cells, and thus regulate intracellular lipid metabolism. The structures of all FABP subtypes are similar, inclusive of two α2 helices arid one β2 fold structure. Among them, the sensitivities and specificities of the heart- and brain-subtype FABPs are higher in the early diagnosis of cardio-cerebrovascular diseases. It is promising to become the novel markers in the early diagnosis of cardio-cerebrovascular diseases.
6.Application of insulation blanket in the esophageal cancer radical surgery
Chinese Journal of Practical Nursing 2009;25(34):36-37
Objective To discuss the application of insulation blanket in the esophageal cancer radical surgery.Methods 40 cases of esophageal carcinoma patients were divided into two groups at random,20 cases involved in the control group (non-use of insulation blankets) and 20 cases in the experimental group (use of thermal insulation blanket).The changes in body temperature of all patients were monitored with nasopharyngeal temperature probe and analyzed in statistics.Results Compared to the control group,the body temperatures of the experimental group were higher.By heating with insulation blanket,the body temperatures were increased obviously in 30 minutes after entering the operation room,but no significant difference appeared at different time points after 30 minutes.Conclusions In radical surgery of esophageal cancer,the use of blanket insulation is an effective way to maintain a constant body temperature of patients and reduce post-operative complications,and promote early recovery of patients.
7.Preparation and purification of polyclonal antibodies against human Fc?/?R and the polymeric immunoglobulin receptor
Chinese Journal of Immunology 1985;0(01):-
Objective:To generate rabbit anti-human Fc?/?R and Poly Immunoglobulin Receptor(pIgR) polyclonal antibodies.Methods:The EC12 domain of human Fc?/?R and the D1 domain of pIgR were expressed as including bodies in Escherichia coli.The purified proteins were used to immunize rabbits to generate polyclonal antibodies.The immune sera were characterized by ELISA and Western blot analysis,then absorbed with cross-action and purified by antigen linked beads.Results:The titers of antiserum were 1∶6 4000 and 1∶25 6000,separately.There was little cross-reaction between the two immune sera.Conclusion:The polyclonal antibodies against human Fc?/?R and pIgR without cross-reaction were successfully generated and could be useful tools to study the relationship between the two receptors.
8.Clinical Observation of Acupunture in Treating Depression and Effect on Serum Cell Factors
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(06):-
Objective To investigate the mechanism of acupuncture in anti-depression. Methods 100 depressive patients were randomly divided into acupuncture group and Amitriptyline group, 50 cases in each group. They were respectively treated by acupuncture at Neiguan (PC6), Sanyinjiao (SP6), Baihui (DU20), Fengchi (GB20), and oral western meicine. The needles were manipulated once every 20 minutes and treatment was given once a day. HAMD score and levels of serum cell factors of two groups were observed. Results Serum levels of interleukin 1? (IL-1?), interleukin-6 (IL-6) interleukin-2 (IL-2) and tumor necorsis factor-? (TNF-?) in depressive subjects before treatment were significanly higher than that of nomal subjects (all P
9.STUDIES ON POLYSACCHARIDE FROM SARGASSUM THUN-BERGII FOR ITS ABILITY TO SCAVENGE ACTIVE OXYGEN SPECIES Ⅱ On Effect of Far Ultraviolet Radiation on Antioxidation of Polysaccharides
Chinese Journal of Marine Drugs 1994;0(03):-
The effect of far ultraviolet radiation on scavenging active oxygen radiacal of polysaccharides from Sargassum thvnbergii and Sargassum kvrneri was studied. The results showed that the scavenging superoxide an ion radiacal levels of two polysaccharides were obviously decreased after 24h by UVc radiation,but the inhibition of the peroxidization of PU-FA was very prominent.The changes of IR spectra before and after far ultraviolet radiation on the two polysac-charide were also studied by differential scanning calorimetry(DSC)and infrared absorption spectroscopy(IR)
10.Study on effect of UC-MSC in IPF experimental model induced by bleomycin in mice
Chinese Journal of Biochemical Pharmaceutics 2015;(11):19-21,25
Objective To investigate protective of umbilical cord-mesenchymal stem cells ( UC-MSC ) on idiopathic pulmonary fibrosis ( IPF ) experimental mode was induced by bleomycin in mice .Methods IPF experimental mode induced by bleomycin with intratracheal injection , and then the fourth generation UC-MSC was injected in caudal vein.The lung tissues were obtained to evaluate the influence of UC-MSC on IPF by the observation of histological evaluation(HE) and Masson staining, the detection content of hydroxyprine(HYP), superoxyde dismutase(SOD) and malonaldehyde ( MDA) .Results The HE and Masson staining showed that bleomycin +UC-MSC group could alleviate inflammatory cell infiltration and pulmonary interstitial collagen deposition.bleomycin+UC-MSC group could decline the content of HYP(P<0.01), MDA(P<0.05) and improve the content of SOD(P<0.01)compared with bleomycin group.Conclusion UC-MSC exhibits an protective effect on IPF experimental mode induced by bleomycin in mice.