3.Cost-Minimization Analysis of 2 Regimens of Reduced Glutathione in the Treatment of Acute Hepatic Lesion in Patients after Undergoing Partial Hepatectomy
Chengliang ZHANG ; Guang DU ; Dong LIU
China Pharmacy 2007;0(35):-
0.05),respectively;the total cost for Group A was significantly higher than in Group B (1 276.54 yuan vs.1 117.57 yuan,P
4. The clinical value of using xMAP technology for detection of high-risk human papillomavirus
Tumor 2008;28(5):431-435
Objective: To explore the clinical values of using flexible multi-analyte profiling (xMAP) technology for detection of high-risk human papillomavirus (HR-HPV). Methods: Six hundred and thirty eight cervical exfoliated cell samples were collected from women who lived in the region with high-incidence of cervical cancer in Shanxi province. The samples were tested with xMAP technology and Hybrid Capture 2 ® Assay (hc2). Pathological diagnosis was used as a hallmark to evaluate the detection results. HR-HPV infection rate and its genotyping distribution were analyzed and the coincidence of two methods above was assessed. Results: The sensitivity, specificity and accuracy of xMAP technology were 77.78%, 93.59% and 92.42%, respectively. The negative and positive predictive values were 98.13% and 49.30%, respectively. The prevalence rate of HR-HPV was 11.7%. HPV16 and 52 were the dominant types in non-neoplastic disease and cervical intraepithelial neoplasia (CIN) grade 1; HPV16 and 58 were the most common types in CIN2 samples; HPV16 was the most frequent type in CIN3 and cervical cancer. The lesion progress was positively related to the infection rate of HPV16, 52 or 58 (P<0.01). The Kappa value for agreement between xMAP technology and hc2 was 0.60. Conclusions: Compared with the hc2 test, the xMAP technology was highly specific, and the sensitivity is 77.78%. The agreement of these two methods is satisfactory. More improvements should be made to elevate the sensitivity of xMAP method and to increase the numbers of genotypes that can be detected.
5.Epithelioid angiosarcoma after radical mastectomy for breast carcinoma: a case report.
Hong-ji DING ; Guo-guang WEI ; Li-qun YU ; Qi-song WU ; Yan-guang DONG
Chinese Journal of Pathology 2006;35(10):637-638
Aged
;
Antigens, CD34
;
metabolism
;
Breast Neoplasms
;
metabolism
;
pathology
;
therapy
;
Chemotherapy, Adjuvant
;
Combined Modality Therapy
;
Epithelioid Cells
;
pathology
;
Female
;
Follow-Up Studies
;
Hemangiosarcoma
;
metabolism
;
pathology
;
Humans
;
Immunohistochemistry
;
Mastectomy, Radical
;
Neoplasms, Second Primary
;
metabolism
;
pathology
;
Radiotherapy, Adjuvant
;
Vimentin
;
metabolism
6.Association of Helicobacter pylori L-form infection with VEGF expression and angiogenesis in gastric cancer.
Ping-guang LEI ; Yan-li LUO ; Dong-hong YU
Chinese Journal of Oncology 2009;31(2):126-127
Adult
;
Aged
;
Aged, 80 and over
;
Female
;
Helicobacter Infections
;
metabolism
;
Helicobacter pylori
;
classification
;
pathogenicity
;
Humans
;
Lymphatic Metastasis
;
Male
;
Microvessels
;
pathology
;
Middle Aged
;
Neoplasm Invasiveness
;
Neovascularization, Pathologic
;
microbiology
;
pathology
;
Stomach Neoplasms
;
blood supply
;
metabolism
;
microbiology
;
Vascular Endothelial Growth Factors
;
metabolism
10.Progress in research on mechanism of pathogenesis and treatment of acute paraquat poisoning.
Yan-jun RUAN ; Xiang-dong JIAN ; Guang-ran GUO
Chinese Journal of Industrial Hygiene and Occupational Diseases 2009;27(2):114-116
Herbicides
;
poisoning
;
Humans
;
Paraquat
;
poisoning
;
Poisoning
;
metabolism
;
pathology
;
therapy