1.Biomechanical study on wing shaped titanium plate fixation of acetabular anterior column and posterior hemi-transverse fracture under multiple working conditions.
Jianwu ZHANG ; WURIKAIXI AIYITI ; Gang LYU ; MAIMAIAILI YUSHAN ; Zhiqiang MA ; Chao MA
Journal of Biomedical Engineering 2025;42(2):351-358
This article aims to compare and analyze the biomechanical differences between wing-shaped titanium plates and traditional titanium plates in fixing acetabular anterior column and posterior hemi-transverse (ACPHT) fracture under multiple working conditions using the finite element method. Firstly, four sets of internal fixation models for acetabular ACPHT fractures were established, and the hip joint stress under standing, sitting, forward extension, and abduction conditions was calculated through analysis software. Then, the stress of screws and titanium plates, as well as the stress and displacement of the fracture end face, were analyzed. Research has found that when using wing-shaped titanium plates to fix acetabular ACPHT fractures, the peak stress of screws decreases under all working conditions, while the peak stress of wing-shaped titanium plates decreases under standing and sitting conditions and increases under forward and outward extension conditions. The relative displacement and mean stress of the fracture end face decrease under all working conditions, but the values are higher under forward and outward extension conditions. Wing-shaped titanium plates can reduce the probability of screw fatigue failure when fixing acetabular ACPHT fractures and can bear greater loads under forward and outward extension conditions, improving the mechanical stability of the pelvis. Moreover, the stress on the fracture end surface is more conducive to stimulating fracture healing and promoting bone tissue growth. However, premature forward and outward extension rehabilitation exercises should not be performed.
Titanium
;
Bone Plates
;
Humans
;
Acetabulum/surgery*
;
Fracture Fixation, Internal/methods*
;
Biomechanical Phenomena
;
Finite Element Analysis
;
Bone Screws
;
Fractures, Bone/surgery*
;
Stress, Mechanical
;
Working Conditions
2.Effects of elastic modulus of the metal block on the condylar-constrained knee prosthesis tibial fixation stability.
Yuhan ZHANG ; Jing ZHANG ; Tianqi DONG ; Xuan ZHANG ; Weijie ZHANG ; Lei GUO ; Zhenxian CHEN
Journal of Biomedical Engineering 2025;42(4):782-789
Although metal blocks have been widely used for reconstructing uncontained tibial bone defects, the influence of their elastic modulus on the stability of tibial prosthesis fixation remains unclear. Based on this, a finite element model incorporating constrained condylar knee (CCK) prosthesis, tibia, and metal block was established. Considering the influence of the post-restraint structure of the prosthesis, the effects of variations in the elastic modulus of the block on the von Mises stress distribution in the tibia and the block, as well as on the micromotion at the bone-prosthesis fixation interface, were investigated. Results demonstrated that collision between the insert post and femoral prosthesis during tibial internal rotation increased tibial von Mises stress, significantly influencing the prediction of block elastic modulus variation. A decrease in the elastic modulus of the metal block resulted in increased von Mises stress in the proximal tibia, significantly reduced von Mises stress in the distal tibia, decreased von Mises stress of the block, and increased micromotion at the bone-prosthesis fixation interface. When the elastic modulus of the metal block fell below that of bone cement, inadequate block support substantially increased the risk of stress shielding in the distal tibia and fixation interface loosening. Therefore, this study recommends that biomechanical investigations of CCK prostheses must consider the post-constraint effect, and the elastic modulus of metal blocks for bone reconstruction should not be lower than 3 600 MPa.
Knee Prosthesis
;
Humans
;
Finite Element Analysis
;
Tibia/surgery*
;
Elastic Modulus
;
Arthroplasty, Replacement, Knee/methods*
;
Stress, Mechanical
;
Metals
;
Prosthesis Design
;
Knee Joint/surgery*
;
Biomechanical Phenomena
3.Structural design and mechanical analysis of a "drum-shaped" balloon-expandable valve stent in expanded configuration.
Youzhi ZHAO ; Qianwen HOU ; Jianye ZHOU ; Shiliang CHEN ; Hanbing ZHANG ; Aike QIAO
Journal of Biomedical Engineering 2025;42(5):945-953
Stent migration is one of the common complications following transcatheter valve implantation. This study aims to design a "drum-shaped" balloon-expandable aortic valve stent to address this issue and conduct a mechanical analysis. The implantation process of the stent was evaluated using a method that combines numerical simulation and in vitro experiments. Furthermore, the fatigue process of the stent under pulsatile cyclic loading was simulated, and its fatigue performance was assessed using a Goodman diagram. The process of the stent migrating toward the left ventricular side was simulated, and the force-displacement curve of the stent was extracted to evaluate its anti- migration performance. The results showed that all five stent models could be crimped into a 14F sheath and enabled uniform expansion of the native valve leaflets. The stress in each stent was below the ultimate stress, so no fatigue fracture occurred. As the cell height ratio decreased, the contact area fraction between the stent and the aortic root gradually decreased. However, the mean contact force and the maximum anti-migration force first decreased and then increased. Specifically, model S5 had the smallest contact area fraction but the largest mean contact force and maximum anti-migration force, reaching approximately 0.16 MPa and 10.73 N, respectively. The designed stent achieves a "drum-shaped" change after expansion and has good anti-migration performance.
Stents
;
Prosthesis Design
;
Heart Valve Prosthesis
;
Humans
;
Aortic Valve/surgery*
;
Stress, Mechanical
;
Transcatheter Aortic Valve Replacement/instrumentation*
4.Effect of lower limb amputation on hemodynamic environment of the left coronary artery: a numerical study.
Tianxiang TAI ; Wentao JIANG ; Zhongyou LI ; Junjie DIAO ; Xiao LI
Journal of Biomedical Engineering 2025;42(5):954-963
It has been found that the incidence of cardiovascular disease in patients with lower limb amputation is significantly higher than that in normal people, and the risk of developing coronary atherosclerosis is much higher than that in other high-risk groups. Numerous studies have confirmed that high systolic and diastolic blood pressures are potential risk factors for coronary artery disease, and it has been demonstrated that the ascending aortic pressure during diastole increases after amputation. However, the relationship between lower limb amputation and coronary atherosclerosis has not been fully explained from the perspective of hemodynamic environment. Therefore, in this study, a centralized parameter model of the human cardiovascular system and a three-dimensional model of the left coronary artery were established to investigate the effect of amputation on the hemodynamic environment of the coronary artery. The results showed that the abnormal hemodynamic environment induced by amputation, characterized by factors such as increased diastolic pressure in the ascending aorta, led to a significant expansion of the low wall shear stress (WSS) region on the outer lateral aspect of the left coronary artery bifurcation during diastole. The maximum observed increase in the area of low WSS reached up to 50.5%. This abnormal hemodynamic environment elevates the risk of plaque formation in the left coronary artery. Moreover, the more severe the lower limb atrophy, the greater the risk of coronary atherosclerosis in amputees. This study preliminarily reveals the effect of lower limb amputation on the hemodynamic environment of the left coronary artery.
Humans
;
Hemodynamics/physiology*
;
Amputation, Surgical/adverse effects*
;
Coronary Vessels/physiology*
;
Coronary Artery Disease/etiology*
;
Lower Extremity/surgery*
;
Models, Cardiovascular
;
Blood Pressure
5.Acquired Anterior Urethral Diverticulum Resulting from Long-Term Use of a Penile Clamp for Incontinence Management Following Prostatectomy: A Case Report.
Xiao-Qin JIANG ; Di GU ; Yin-Hui YANG
Chinese Medical Sciences Journal 2025;40(2):157-160
We report a case involving an 85-year-old man who underwent laparoscopic radical prostatectomy for prostate cancer in 2011. During follow-up, he required long-term use of a penile clamp to manage urination due to permanent severe stress incontinence. In February 2023, he presented with a painless cystic mass in the scrotum. Upon pressing the mass with hand, fluid drained from the external urethral orifice, causing the mass to shrink in size, although it returned to its original size a few hours later. Urography and cystoscopy showed a globular urethral diverticulum located anteriorly. The patient underwent surgical excision of the diverticulum along with urethroplasty. Postoperatively, the urinary stress incontinence persisted, but he declined any further surgical intervention. An artificial urinary sphincter is currently the first-line treatment for male urinary incontinence. However, devices such as penile clamps can serve as an alternative when considering surgical suitability or cost. It is important to note that these devices can lead to serious complications such as urethral erosion, stricture, or diverticulum. Therefore, caution is advised when using such devices, and they should be removed periodically at short intervals.
Humans
;
Male
;
Diverticulum/surgery*
;
Prostatectomy/adverse effects*
;
Aged, 80 and over
;
Urethral Diseases/surgery*
;
Urinary Incontinence/surgery*
;
Urinary Incontinence, Stress/surgery*
6.Risk Factors for Prolonged Postoperative Length of Stay After Hip Fracture Surgery in Very Elderly Patients.
Bo-Wen XU ; Wei-Yun CHEN ; Chen SUN ; Ling LAN ; Lu-Lu MA ; Li-Jian PEI
Chinese Medical Sciences Journal 2025;40(2):111-119
OBJECTIVES:
To identify risk factors contributing to prolonged postoperative length of stay (LOS) in very elderly patients following hip fracture surgery, with a focus on postoperative complications and the impact of different anesthesia approaches.
METHODS:
This retrospective single-center cohort study enrolled patients aged 90 years or older who underwent hip fracture surgery at Peking Union Medical College Hospital between January 31, 2013 and December 31, 2023. Relevant perioperative data were collected. The primary outcome was postoperative LOS, and the study cohort was divided into two groups: postoperative LOS ≤ 7 days and LOS > 7 days. Logistic regression was performed to identify factors related to prolonged postoperative LOS.
RESULTS:
A total of 155 patients were included. The average age was 92.7 ± 2.6 years. There were 73 (47%) patients with postoperative LOS > 7 days. Postoperative pneumonia was the only factor associated with a prolonged postoperative LOS (OR = 2.12, 95% CI [1.09, 4.16], P = 0.028). Neither the type of anesthesia (regional vs. general anesthesia, OR = 1.00, 95% CI [0.53, 1.90], P = 0.993) nor the method of airway management (laryngeal mask ventilation vs. spontaneous breathing, OR = 1.46, 95% CI [0.58, 3.76], P = 0.424; endotracheal intubation vs. spontaneous breathing, OR = 0.82, 95% CI [0.39, 1.69], P = 0.592) showed a significant association with a prolonged postoperative LOS. Preoperative chronic obstructive pulmonary disease (OR = 2.78, 95% CI [1.05, 7.65], P = 0.040) and preoperative neutrophil count (OR = 1.13, 95% CI [1.01, 1.26], P = 0.029) were both significantly associated with the occurrence of postoperative pneumonia, while anesthesia type and airway management method were not.
CONCLUSIONS
Postoperative pneumonia was associated with prolonged postoperative LOS in very elderly patients undergoing hip fracture surgery, whereas anesthesia types and airway management methods show no association with prolonged postoperative LOS or postoperative pneumonia. Preoperative comorbidities, especially respiratory conditions and systemic inflammation, potentially play a substantial role in postoperative recovery.
Humans
;
Hip Fractures/surgery*
;
Aged, 80 and over
;
Risk Factors
;
Length of Stay
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Female
;
Male
;
Retrospective Studies
;
Postoperative Complications/etiology*
7.Clinical application standard of dynamic navigation technology in implant surgery.
Chinese Journal of Stomatology 2025;60(2):105-108
Dynamic navigation technology can "real-time guide" the implantologist to place the implant in the alveolar bone of the missing tooth area according to the preoperative design of the optimal site and path, making the whole implant surgery process more safe and precise. In order to further promote the standardized application of oral implant dynamic navigation technology, China Association of Gerontology and Geriatrics has convened distinguished experts to engage in deliberations and develop the standard. This standard covers the basic requirements, indications and contraindications, operation procedures, common complications and treatment measures, and accuracy verification. This standard can be used as a reference for the use of dynamic navigation technology in implant surgery.
Humans
;
Dental Implantation, Endosseous/standards*
;
Surgery, Computer-Assisted/standards*
;
Dental Implants
;
Surgical Navigation Systems/standards*
8.Revision of anterior cruciate ligament reconstruction: Interpretation of the consensus by the European Society of Sports Traumatology, Knee Surgery and Arthroscopy (ESSKA).
Chinese Journal of Reparative and Reconstructive Surgery 2025;39(1):1-4
Revision of anterior cruciate ligament (ACL) reconstruction is more challenging than primary ACL reconstruction and often yields less favorable outcomes. The European Society of Sports Traumatology, Knee Surgery and Arthroscopy (ESSKA) has established a consensus regarding preoperative diagnosis, assessment, and selection criteria for ACL revision surgery. This consensus addresses 18 key issues that are most pertinent to clinical practice, providing guiding recommendations aimed at improving the prognosis of ACL revisions.
Humans
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Anterior Cruciate Ligament Reconstruction/methods*
;
Arthroscopy/methods*
;
Anterior Cruciate Ligament Injuries
;
Societies, Medical
;
Reoperation
;
Consensus
;
Anterior Cruciate Ligament/surgery*
;
Europe
;
Sports Medicine
;
Knee Injuries/surgery*
;
Knee Joint/surgery*
9.Early effectiveness of navigation-free robot-assisted total knee arthroplasty in treating knee osteoarthritis with extra-articular deformities.
Chen MENG ; Yongqing XU ; Rongmao SHI ; Luqiao PU ; Jian'an JI ; Xingyou YAO ; Xizong ZHOU ; Chuan LI
Chinese Journal of Reparative and Reconstructive Surgery 2025;39(1):5-12
OBJECTIVE:
To evaluate the early effectiveness of navigation-free robot-assisted total knee arthroplasty (TKA) compared to traditional TKA in the treatment of knee osteoarthritis combined with extra-articular deformities.
METHODS:
The clinical data of 30 patients with knee osteoarthritis combined with extra-articular deformities who met the selection criteria between June 2019 and January 2024 were retrospectively analyzed. Fifteen patients underwent CORI navigation-free robot-assisted TKA and intra-articular osteotomy (robot group) and 15 patients underwent traditional TKA and intra-articular osteotomy (traditional group). There was no significant difference in age, gender, body mass index, affected knee side, extra-articular deformity angle, deformity position, deformity type, and preoperative knee range of motion, American Knee Society (KSS) knee score and KSS function score, and lower limb alignment deviation between the two groups ( P>0.05). The operation time, intraoperative blood loss, and complications of the two groups were recorded and compared. The knee range of motion and lower limb alignment deviation were recorded before operation and at 6 months after operation, and the knee joint function was evaluated by KSS knee score and function score.
RESULTS:
There was no significant difference in operation time between the two groups ( P>0.05); the intraoperative blood loss in the robot group was significantly less than that in the traditional group ( P<0.05). Patients in both groups were followed up 6-12 months, with an average of 8.7 months. The incisions of all patients healed well, and there was no postoperative complication such as thrombosis or infection. At 6 months after operation, X-ray examination showed that the position of the prosthesis was good in both groups, and there was no loosening or dislocation of the prosthesis. The knee joint range of motion, the lower limb alignment deviation, and the KSS knee score and KSS function score significantly improved in both groups ( P<0.05) compared to preoperative ones. The changes of lower limb alignment deviation and KSS function score between pre- and post-operation in the robot group were significantly better than those in the traditional group ( P<0.05), while the changes of other indicators between pre- and post-operation in the two groups were not significant ( P>0.05).
CONCLUSION
Compared to traditional TKA, navigation-free robot-assisted TKA for knee osteoarthritis with extra-articular deformities results in less intraoperative blood loss, more precise reconstruction of lower limb alignment, and better early effectiveness. However, long-term effectiveness require further investigation.
Humans
;
Arthroplasty, Replacement, Knee/methods*
;
Osteoarthritis, Knee/surgery*
;
Robotic Surgical Procedures/methods*
;
Male
;
Female
;
Retrospective Studies
;
Range of Motion, Articular
;
Middle Aged
;
Aged
;
Treatment Outcome
;
Osteotomy/methods*
;
Knee Joint/physiopathology*
;
Operative Time
10.Application of personalized three-dimensional printed customized prostheses in severe Paprosky type Ⅲ acetabular bone defects.
Shuailei LI ; Hao CHAI ; Yongqiang SUN
Chinese Journal of Reparative and Reconstructive Surgery 2025;39(1):13-19
OBJECTIVE:
To analyze the short-term effectiveness and safety of personalized three-dimensional (3D) printed customized prostheses in severe Paprosky type Ⅲ acetabular bone defects.
METHODS:
A retrospective analysis was conducted on 8 patients with severe Paprosky type Ⅲ acetabular bone defects and met the selection criteria between January 2023 and June 2024. There were 3 males and 5 females, with an average age of 64.6 years ranged from 56 to 73 years. All primary replacement prostheses were non-cemented, including 1 ceramic-ceramic interface, 1 ceramic-polyethylene interface, and 6 metal-polyethylene interfaces. The time from the primary replacement to the revision was 4 days to 18 years. The reasons for revision were aseptic loosening in 5 cases, revision after exclusion in 2 cases, and repeated dislocation in 1 case. The preoperative Harris score was 39.5±3.7 and the visual analogue scale (VAS) score was 7.1±0.8. The operation time, intraoperative blood loss, hospital stay, and complications were recorded. The hip function was evaluated by Harris score, and the degree of pain was evaluated by VAS score. The acetabular cup abduction angle, anteversion angle, rotational center height, greater trochanter height, and femoral offset were measured on X-ray film.
RESULTS:
The operation time was 95-223 minutes, with an average of 151.13 minutes. The intraoperative blood loss was 600-3 500 mL, with an average of 1 250.00 mL. The hospital stay was 13-20 days, with an average of 16.88 days. All 8 patients were followed up 2-12 months, with an average of 6.4 months. One patient had poor wound healing after operation, which healed well after active symptomatic treatment. One patient had lower limb intermuscular vein thrombosis, but no thrombosis was found at last follow-up. No serious complications such as aseptic loosening, infection, dislocation, and periprosthetic fracture occurred during the follow-up. At last follow-up, the Harris score was 72.0±6.2 and the VAS score was 1.8±0.7, which were significantly different from those before operation ( t=-12.011, P<0.001; t=16.595, P<0.001). On the second day after operation, the acetabular cup abduction angle ranged from 40° to 49°, with an average of 44.18°, and the acetabular cup anteversion angle ranged from 19° to 26°, with an average of 21.36°, which were within the "Lewinneck safety zone". There was no significant difference in the rotational center height, greater trochanter height, and femoral offset between the healthy side and the affected side ( P>0.05).
CONCLUSION
The use of personalized 3D printed customized prostheses for the reconstruction of severe Paprosky type Ⅲ acetabular bone defects can alleviate pain and enhances hip joint function, and have good postoperative prosthesis position, without serious complications and have good safety.
Humans
;
Printing, Three-Dimensional
;
Male
;
Female
;
Middle Aged
;
Acetabulum/surgery*
;
Aged
;
Retrospective Studies
;
Hip Prosthesis
;
Prosthesis Design
;
Arthroplasty, Replacement, Hip/instrumentation*
;
Reoperation
;
Treatment Outcome

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