1.2024 EAU/ESPU paediatric urology guidelines: key updates on congenital lower urinary tract obstruction and clinical inter-pretation.
Lingli MEI ; Zhihui ZHENG ; Chang TAO ; Guangjie CHEN ; Xiang YAN
Journal of Zhejiang University. Medical sciences 2025;54(5):583-591
Congenital lower urinary tract obstruction (CLUTO) is a spectrum of fetal malformations caused by anatomical abnormalities of the urethra, characterized by high rates of perinatal complications and mortality. The 2024 joint guideline from the European Association of Urology (EAU) and the European Society for Paediatric Urology (ESPU) introduced systematic revisions to the comprehensive management of CLUTO. Key updates encompass advancements in prenatal and postnatal screening and precise diagnosis, refined fetal prognosis assessment, clearer indications and modality selection for prenatal intervention, optimization of postnatal treatment strategies, and the establishment of a lifelong follow-up framework within an integrated care pathway. This article elucidates these key updates by comparing the 2024 EAU/ESPU guideline with the 2022 European Rare Kidney Disease Reference Network (ERKNet) consensus. It also discusses ongoing controversies and future research directions. The aim is to provide clinicians with the latest evidence-based insights to inform practice, ultimately improving outcomes and quality of life for children with CLUTO.
Humans
;
Urology
;
Female
;
Urethral Obstruction/therapy*
;
Pregnancy
;
Child
;
Europe
;
Prenatal Diagnosis
;
Infant, Newborn
;
Urethra/abnormalities*
2.Urology action plan in a pandemic.
Reshma MANGAT ; Sarvajit BILIGERE ; Chin Tiong HENG ; Pradeep DURAI ; Vineet GAUHAR
Singapore medical journal 2023;64(4):271-275
3.Research hotspots of prostate cancer at the international conferences on urology in 2022.
Jiahe YI ; Jiangfeng LI ; Liping XIE
Journal of Zhejiang University. Medical sciences 2023;52(2):178-184
The American Urological Association (AUA), European Association of Urology (EUA) and International Urological Society (SIU) annual meetings were held in 2022. Studies on prostate cancer reported in the meetings mainly focus on the advances of diagnostic biomarkers (such as α-2, 3-1inked sialylation of terminal N-glycan on free PSA density, SelectMDx) and imaging techniques [such as multiparametric magnetic resonance imaging, prostate specific membrane antigen(PSMA)-PET/CT], the new method for prostate biopsy, the new treatments of prostate cancer including [177Lu] Ludotadipep and DROP-IN PSMA probe, and the prognosis assessment of prostate cancer (such as AR-V7). This article provides an overview on the research hotspots of three international academic meetings.
Male
;
Humans
;
Urology
;
Positron Emission Tomography Computed Tomography/methods*
;
Prostatic Neoplasms/pathology*
;
Multiparametric Magnetic Resonance Imaging/methods*
;
Gallium Radioisotopes
5.Development and prospect of tissue engineering in urology.
Journal of Biomedical Engineering 2020;37(2):193-199
Tissue engineering technology and stem cell research based on tissue engineering have made great progresses in overcoming the problems of tissue and organ damage, functional loss and surgical complications. Traditional method is to use biological substitute materials to repair tissues, while tissue engineering technology focuses on combining seed cells with biological materials to form biological tissues with the same structure and function as its own to repair tissue defects. The advantage is that such tissue engineering organs and tissues can solve the problem that the donor material is limited, and effectively reduce complications. The purpose of tissue engineering is to find suitable seed cells and biomaterials which can replace the biological function of original tissue and build suitable microenvironment . This paper mainly describes current technologies of tissue engineering in various fields of urology, and discusses the future trend of tissue engineering technology in the treatment of complex urinary diseases. The results of this study show that although there are relatively few clinical trials, the good results of the existing studies on animal models reveal a bright future of tissue engineering technology for the treatment of various urinary diseases.
Animals
;
Biocompatible Materials
;
Humans
;
Tissue Engineering
;
trends
;
Tissue Scaffolds
;
Urology
;
trends
6.The development status of interdisciplinary combination between medicine and engineering in urology: deep integration between medicine and engineering in urology.
Journal of Biomedical Engineering 2020;37(2):189-192
Urology is an ancient academic discipline, and its rapid development is due to the combination between medicine and engineering. The development of urology in China is an example of the combination of industry-academia-research based on the progress of science and technology. This paper mainly summarizes the recent advances of interdisciplinary combination between medicine and engineering in urology.
Biomedical Engineering
;
trends
;
China
;
Humans
;
Interdisciplinary Research
;
Urology
;
trends
7.Fundamentals of prosthetic urology.
Asian Journal of Andrology 2020;22(1):20-27
The field of prosthetic urology demonstrates the striking impact that simple devices can have on quality of life. Penile prosthesis and artificial urinary sphincter implantation are the cornerstone procedures on which this specialty focuses. Modern research largely concentrates on decreasing the rates of complication and infection, as the current devices offer superior rates of satisfaction when revision is not necessary. These techniques are also able to salvage sexual function and continence in more difficult patient populations including female-to-male transgender individuals, those with ischemic priapism, and those with erectile dysfunction and incontinence secondary to prostatectomy. This review summarizes modern techniques, outcomes, and complications in the field of prosthetic urology.
Erectile Dysfunction/surgery*
;
Humans
;
Male
;
Penile Implantation/methods*
;
Penile Prosthesis
;
Postoperative Complications/epidemiology*
;
Prostatectomy/adverse effects*
;
Prosthesis Failure
;
Prosthesis Implantation/methods*
;
Prosthesis-Related Infections/epidemiology*
;
Surgical Wound Infection/epidemiology*
;
Urethra/injuries*
;
Urinary Incontinence, Stress/surgery*
;
Urinary Retention/epidemiology*
;
Urinary Sphincter, Artificial
;
Urology
8.The Current Status of Development of Korean Clinical Practice Guidelines in Urology
Korean Journal of Urological Oncology 2019;17(1):1-6
The clinical practice guidelines (CPGs) is made step by step. The evidences that have been published were searched and a group of experts make a consensus based in the evidences. The CPGs in the medical field, where utilizations and interests are increasing, must be confirmed in the management of quality. The Korean Appraisal of Guidelines for Research & Evaluation II (K-AGREE II) tool that helps to manage the quality of CPGs and to develop CPGs was translated by the Steering Committee for Clinical Practice Guideline. It is divided into 6 domains and each domains are independent. It is consisted of 23 items as detail and 2 items for the overall evaluation. Only fifteen CPGs are successfully certified using the K-AGREE II tool in the Korean Medical Guideline Information Center from 2013 and 3 CPGs made by the Korea Urological Association and the associated societies are certified successfully. With the level of certification of CPGs is higher, the Korea Urological Association and the associated societies are also try to develop CPGs that meet their level of certification. The Korean clinical practice guideline for the treatment of prostate cancer developed recently is the evidence of effort.
Certification
;
Consensus
;
Information Centers
;
Korea
;
Prostatic Neoplasms
;
Quality Improvement
;
Urology
9.A universal ultrasound diagnostic system developed to support urology and coloproctological applications
Jeong Seok KIM ; Jong Gun LEE ; Jae Hyeok CHOI ; Bong Hyo HAN ; Se Leang YOON ; Ho JUNG ; Tai Kyong SONG ; Jae Young LEE
Biomedical Engineering Letters 2019;9(1):119-125
In this study, we sought to describe a novel imaging apparatus that is lightweight, inexpensive, and highly eff ective for use in colorectal diagnostic and treatment settings. Typical probes for use in colorectal ultrasonic imaging applications are developed for surgeons to diagnose and stage rectal tumors and image the rectum and anus. Here we outline a new technique and use it for colorectal imaging in an animal. This technique involves use of an ultrasound array module positioned along the axis of rotation such that improved rotation is possible. This module is in the shape of a linear rod with a rotary linear component that allows for emission of focused ultrasonic echo signals from a linear section of the probe. The usability of the transducer and rectal image quality are satisfactory in a porcine model with the technique proposed here, axial/lateral resolution as 0.96/2.24 mm with 6 dB applied through the contour map using the point spread function. When compared to currently available methods, this technique provides superior diagnostic 3D volumetric image quality with reduced acquisition time. Given this, the ultrasound device proposed here may prove a viable and preferable method to those currently available for urology and colorectal imaging applications.
Anal Canal
;
Animals
;
Methods
;
Rectal Neoplasms
;
Rectum
;
Surgeons
;
Transducers
;
Ultrasonics
;
Ultrasonography
;
Urology
10.Choroidal Effusion after Consecutive General Anesthesia
Journal of the Korean Ophthalmological Society 2019;60(9):892-895
PURPOSE: To report a case of extensive choroidal effusion following the Valsalva maneuver under consecutive general anesthesia. CASE SUMMARY: A 41-year-old man who underwent panretinal photocoagulation with proliferative diabetic retinopathy had pars plana vitrectomy and endolaser photocoagulation under general anesthesia due to vitreous hemorrhage. Urology cooperated as the patient had hematuria; the day after the operation, he was transferred to the urology department. Two days after vitrectomy, the patient had an urgent transurethral bladder tumor resection under general anesthesia with suspicion of bladder tumor. At 6 days postoperatively, extensive choroidal effusion was observed from 8 to 10 o'clock on fundus examination and ultrasonography. On day 23 after urological surgery, the choroidal effusion had disappeared without treatment. CONCLUSIONS: Consecutive general anesthesia requires caution, as it is not only burdensome to the body as a whole but may also cause choroidal effusion in the eye.
Adult
;
Anesthesia, General
;
Choroid
;
Diabetic Retinopathy
;
Hematuria
;
Humans
;
Light Coagulation
;
Ultrasonography
;
Urinary Bladder Neoplasms
;
Urology
;
Valsalva Maneuver
;
Vitrectomy
;
Vitreous Hemorrhage

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