1.A Systematic Literature Review on ICU Nurses’ Experience and Family Interactions during Death and Dying from an Islamic Perspective
The International Medical Journal Malaysia 2026;25(No. 2):9-19
The growing complexity of death and dying in Intensive Care Units highlights nurses'
critical role, particularly concerning family interactions and spiritual needs from an
Islamic perspective. However, there is a gap in understanding the nuances of these
interactions, how nurses can best facilitate them, and how potential conflicts arising
from differing interpretations of religious beliefs may impact care; this area remains
underexplored. This systematic literature review aims to synthesize existing studies
on ICU nurses' experiences with critically ill patients during death and dying, focusing
on Islamic perspectives or spiritual care, employing a qualitative synthesis approach.
The Scopus database was used to retrieve relevant documents published between
2005 and 2024. The review followed PRISMA guidelines for identification, screening,
exclusion, and inclusion. Qualitative, quantitative, mixed-method studies, and review
articles were included, with only qualitative papers appraised using the Joanna Briggs
Institute’s criteria. Initially, 378 records were identified. After removing unavailable
files and screening, 113 titles and abstracts were assessed. Of 84 reports reviewed for
eligibility, 68 were excluded, leaving 14 studies that met the inclusion criteria for the
final review. This review emphasizes the crucial need for better training, policies, and
institutional support for ICU nurses. Such measures would enable them to manage the
complexities of culturally sensitive care for family members during loved ones' death
and dying. Implementing standardized guidelines addressing Islamic perspectives can
significantly improve care quality and patient-family satisfaction.
2.A Bibliometric Analysis of Chatbot or ChatGPT in Nursing Fields from 2022 to 2024
Ab Razak NI ; Muhammad Yusoff MF ; Nasharuddin NA ; Soh KL ; O.K. Rahmat O.K. Rahmat RW
The International Medical Journal Malaysia 2026;25(No. 2):20-30
Nursing education has undergone a significant transformation as a result of artificial
intelligence (AI). Chatbots, specifically ChatGPT, have emerged as vital AI
technologies within the nursing domain as it is a computer program designed to
simulate human conversation through text or voice interactions. This study aims to
conduct a bibliometric analysis to gain insights into the publication trends, citation
impact, and thematic evolution in nursing education and practice concerning ChatGPT
and chatbots. A comprehensive bibliometric analysis was performed using
VOSViewer, concentrating on citation networks for data analysis and visualisation. A
review of LENS.org identified 344 relevant research publications regarding chatbots
and ChatGPT within the nursing discipline, all of which were utilised in the study. The
study examined various aspects, including types of publications, prominent authors,
leading journals, participating nations, institutions, and the impact of ChatGPT on
nursing practice. The primary objectives included categorising the papers, identifying
the most influential authors, delineating the prominent areas and institutions in the
field, and examining the impact of ChatGPT on nursing education and practice. The
findings indicate that ChatGPT positively impacts nursing education by enhancing
learning experiences, improving communication, and aiding clinical decision-making.
The findings indicate that journal articles accounted for 76% of publications, with the
U.S. leading in research output. The findings indicate that ChatGPT positively impacts
nursing education by enhancing learning experiences, improving communication, and
aiding clinical decision-making. Future research should focus on establishing
frameworks for integrating ChatGPT into nursing education, addressing ethical
implications, and assessing the long-term impacts on patient care.
3.Recent Updates on the Mechanism of Action of Spirulina as an Anticancer Agent Against Breast Cancer
The International Medical Journal Malaysia 2026;25(No. 2):31-37
Spirulina, a small blue-green algae that lives in warm, alkaline seas, is one of the world's
oldest life forms. With century-old history, this nutrient-rich organism has received a
lot of interest in recent years for its possible health benefits and sustainable production
practices. Studies have indicated its antioxidant, anti-cancer, and anti-inflammatory
qualities are contributed by its bioactive compounds, mainly phycocyanin. Other
compounds or elements include phycocyanobilin, carotenoids, unsaturated fatty acids,
selenium, and amino acids. Breast cancer is one of the major causes of cancer related
death in women. As some of the cancer therapies are highly associated with side
effects, nutraceuticals such as Spirulina could be an alternative therapeutic intervention.
Although some research has been conducted to investigate the anti-breast cancer
effects of Spirulina in the past, its mechanism of action is not entirely understood.
Previous studies suggest that it may trigger apoptosis and autophagy via modifying
signalling pathways such as NF-κB and Bcl-2/Bax ratio. It also has anti-proliferative
properties, inhibits cell migration, causes cell cycle arrest, and lowers cancer cells'
capacity to form colonies. Phycocyanin has been shown to produce reactive oxygen
species (ROS) and down-regulate anti-apoptotic molecules, which contribute to its
anticancer capabilities. These findings show that Spirulina fights cancer by targeting a
variety of cellular mechanisms involved in carcinogenesis. While these data imply
potential benefits, more clinical trials and research into the exact mechanisms of
Spirulina in cancer treatments are needed to fully demonstrate its efficacy in treating
breast cancer in humans.
4.Prevalence of Erectile Dysfunction and Its Associated Factors among Non-Diabetic Overweight & Obese Patients Attending Government Health Clinics in Kuantan, Pahang
Che&rsquo ; Man M ; Mohd Zainal AZAR ; Yusof MZ
The International Medical Journal Malaysia 2026;25(No. 2):38-46
INTRODUCTION: In the clinical setting, erectile dysfunction (ED) is a significant issue
that should not be neglected, as it can adversely impact the quality of life of patients
and their partners, especially among overweight and obese populations. This study
aims to determine the prevalence of ED and its associated factors among non-diabetic,
overweight, and obese patients who attend a government health clinic in Kuantan,
Pahang, Malaysia. MATERIALS AND METHODS: A six-month cross-sectional study
was conducted from February 2024 to August 2024 at twelve health clinics in
Kuantan, Pahang. The selected respondents were married men over 18 years old, and
those with diabetes mellitus, cardiovascular disease, psychiatric illness, or illiteracy were
excluded. Data were collected using the validated Malay version of the International
Index of Erectile Function (IIEF-5). ED was defined as an IIEF-5 score of less than
22. Descriptive analysis and simple and multiple logistic regression were performed
using SPSS. RESULTS: All 221 eligible patients in the study responded (100% response
rate). The prevalence of ED was 66.1% (n=146). Multiple logistic regression
showed that ED was significantly associated with dyslipidemia [AOR (95% CI): 2.42
(1.06–5.52); p-value=0.036], anxiety [AOR (95% CI): 3.99 (1.44–11.01);
p-value=0.008] and older age [AOR (95% CI): 1.07 (1.02–1.12); p-value=0.009].
CONCLUSION: The study revealed a high prevalence of ED among non-diabetic
overweight and obese patients, potentially linked to increasing age, dyslipidemia, and
anxiety. Increasing awareness among the public and healthcare providers could
improve detection rates in primary care.
5.Factors Affecting Triple Elimination Testing Participation by the Pregnant Women During Their First Visit (K1) at Harapan Baru Health Center, East Kalimantan
Tuti Meihartat ; Prita Maharani ; Sumiat ; Aries Abiyoga ; Leny Suzana Suddin
The International Medical Journal Malaysia 2026;25(No. 2):47-54
INTRODUCTION: Mother-to-child-transmission of HIV, syphilis and hepatitis
B is a significant public health issue in Indonesia. Triple elimination screening,
which tests these three infections, is a crucial strategy for early detection and
prevention, ideally conducted during the first antenatal visit (K1). However,
the coverage of this screening remains suboptimal in several regions, including
the Harapan Baru Health Center. This study aimed to test factors affecting
participation in the triple elimination screening during the first antenatal visit
among pregnant women in the service area of the Harapan Baru Health
Center. MATERIALS AND METHODS: A cross-sectional study was conducted
involving 50 pregnant women who attended their K1 visit in June 2025.
Participants were selected using convenience sampling. Data were gathered
through structured questionnaires and maternal and child health (MCH)
books and analysed using the Pearson chi-square test. RESULTS: Respondents’
knowledge (OR=5.4, p=0.023) and health worker support (OR=10.7,
p=0.002;) were significantly associated with screening participation. However,
the education level was not significantly associated. CONCLUSION: Good
knowledge level and positive support from health workers could increase the
likelihood of pregnant women undergoing triple elimination screening during
their first antenatal visit.
6.Development of Components for A Glaucoma Screening Programme in Malaysia: A Qualitative Study
Hui WX WX ; Sharanjeet-Kaur S ; Hairol M M ; Abd Rahman MH ; Nasaruddin RA ; Md Isa Z ; Ismail R ; Che Hamzah J
The International Medical Journal Malaysia 2026;25(No. 2):55-63
INTRODUCTION: Glaucoma is a leading cause of permanent blindness, often going
undetected in its early, asymptomatic stages, especially in older age groups. In
Malaysia, glaucoma is a growing public health issue due to an increase in the ageing
population. While screening is essential for early glaucoma detection, the most
suitable strategy for Malaysia's healthcare system remains unclear. This study
explored the perspectives of eye healthcare professionals on the most suitable
glaucoma screening strategies for Malaysia. MATERIAL AND METHODS: This
qualitative study used semi-structured interviews with 19 eye health professionals
(ophthalmologists, optometrists, nurses, ophthalmic technicians, and assistant
medical officers) practicing in the Klang Valley. The interviews were conducted
face-to-face in their workplace or via a video conferencing platform. All interviews
were recorded, transcribed, and analysed using thematic analysis. RESULTS: Six
major themes were identified: types of glaucoma screening programmes, accessible
screening locations, target screening population, instruments and use of digital
technology, trained personnel, and referral criteria. Opportunistic case finding and
population-based programmes were identified as the glaucoma screening
programmes in which trained personnel conducted screening at accessible
locations. Glaucoma screening for high-risk individuals was recommended,
focusing on visual acuity testing, tonometry, anterior chamber angle assessment,
funduscopy, perimetry, and retinal nerve fibre assessment. A lack of clear referral
criteria due to low awareness and poor implementation of existing guidelines was
observed. CONCLUSION: Further investigations are required to identify the best
combination of components for glaucoma screening. This will enable policymakers
to develop an effective glaucoma screening programme in Malaysia.
7.Malaysia’s third COVID-19 wave – a paradigm shift required
Lekhraj Rampal ; Liew Boon Seng
The Medical Journal of Malaysia 2021;76(1):1-4
The first case of COVID-19 was reported in Malaysia on the
25 January 2020. By the 20 January 2021, the cumulative
numbers reported confirmed cases of COVID-19 had
reached 169,379 including 630 deaths. Malaysia has been hit
by three waves of COVID-19. This article reports on the three
waves, the current situation and some of the possible
factors associated. It outlines the need to reassess the
overall situation, re-strategize the approach in order to
contain the spread. The first COVID-19 wave lasted from 25
January to 16 February 2020, the second wave occurred
between the 27 February 2020 and the 30 June 2020. The
current third wave began on 8th September 2020.The
sudden surge of cases in the third wave was mainly due to
the two largest contributors, namely the Benteng Lahad
Datu cluster in Sabah state and Kedah's Tembok cluster. The
current situation is critical. The daily confirmed cases of
COVID-19 continue to soar. The challengers faced by
healthcare workers and other front liners is tremendous.
Non-communicable diseases such as cardiovascular
diseases, diabetes and cancer are the leading cause of
death in Malaysia. A paradigm shift in the approach is
required to ensure the sustainability of the normal
healthcare services provided by the government especially
for the lower income groups. There is also a need to
expedite the tabling of Tobacco Control Bill in coming
parliament session which is long overdue. H.E. the King of
Malaysia has called on all Malaysians to put aside political,
racial and religious differences and show the spirit of
loyalty, humanitarianism and steadfastness in fighting the
COVID-19 pandemic.
8.Reflections on the MMA CPD system
The Medical Journal of Malaysia 2021;76(1):5-11
The Malaysian Medical Association (MMA) is the body that
represents registered medical practitioners in Malaysia. In
1994, it introduced a national Continuing Medical Education
(CME) system on a voluntary basis for all doctors in the
country. As a longstanding member of the MMA Continuing
Professional Development (CPD) Committee, I wish to record
some reflections on the MMA CPD System and document the
history and the pioneering work of MMA in the area of CPD.
9.Clinical outcomes of acute stroke thrombolysis in neurologist and non-neurologist centres – A comparative study in Malaysia
Sin Hong Chew ; Irene Looi ; Kar Keong Neoh ; Joshua Ooi ; Wee-Kooi Cheah ; Zariah Binti Abdul Aziz
The Medical Journal of Malaysia 2021;76(1):12-16
Acute ischaemic stroke (AIS) is a devastating disease and one
of the leading causes of disabilities worldwide. From 2010 to
2014, the incidence of stroke in Malaysia had increased from
65 to 187 per 100,000 population.1 Thrombolytic therapy
with intravenous recombinant tissue plasminogen activator
(rtPA) within 4.5 hours of symptom onset has been shown to
be an effective treatment for AIS. Patients who receive
thrombolysis are 30 percent more likely to achieve excellent
functional outcome (modified Rankin scale of 0 to 1) at 3
months compared to placebo.2
Unfortunately, the delivery of stroke thrombolysis service in
Malaysia is often limited by the availability of neurologists.
To date, the ratio of neurologists capable of performing
thrombolysis serving in public hospitals to the Malaysian
population is 1:1.4 million.3 To counteract this disparity
and to cope with the increasing stroke burden in Malaysia,
there has been an advocacy for greater involvement of
non-neurologists, i.e., general and emergency physicians
in performing of stroke thrombolysis.4 Emerging data based
on short term outcomes appear to support this notion.
Based on a 2015 single center study on 49 AIS patients in
Australia, A. Lee et al., reported that there was no significant
difference in door to needle time, rates of symptomatic
intracranial bleeding (SICH), and mortality between patients
thrombolysed by neurologists versus stroke physicians.5
In
2016, a larger multicentre study in Thailand reported that
patients thrombolysed in hospitals without neurologists had
lower National Institute of Health Stroke Scale (NIHSS) scores
at discharge and lower inpatient mortality rate compared to
patients treated in neurologist hospitals.6 Based on these
short term outcomes, both studies suggest that nonneurologists are able to thrombolyse AIS patients safely and
effectively. Data comparing long term functional outcomes
in thrombolysis prescribed by neurologists and nonneurologists are still very limited.
The primary objective of this study was to evaluate and
compare the 3-month functional outcomes of thrombolytic
therapy between hospitals with and without on-site
neurologists. The secondary objective was to assess the doorto-needle time and complication rates of thrombolysis service
in both hospitals
10.Vasospasm and delayed cerebral ischaemia in patients with spontaneous subarachnoid haemorrhage (aneurysmal and pretruncal non-aneurysmal): a centre’s perspective
Narendra Balasekaran ; Shahrul Aiman Soelar ; Lalita Anbarasen ; Chun Yoong Cham ; Retnagowri Rajandram ; Sheau Fung Sia
The Medical Journal of Malaysia 2021;76(1):17-23
Spontaneous subarachnoid haemorrhage (SAH) is a
significant cause of stroke and may lead to severe
neurological deficit or death. It is also associated with high
morbidity and mortality for patients despite optimal medical
and surgical treatment. Based on the World Health
Organization the annual incidence of spontaneous SAH
varies in different regions of the world between
2.0-22.5 per 100,000 populations with Finland and
Japan having the highest incidence and South and
Central America with lowest incidence.1


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