1.The acceptance of stroke telerehabilitation among rehabilitation providers and consumers in two tertiary hospitals in the Philippines.
Francis Exequiel M. LAXAMANA ; Marvin Louie S. IGNACIO ; Reynaldo R. REY-MATIAS ; Carl Froilan D. LEOCHICO
Acta Medica Philippina 2026;60(8):37-50
BACKGROUND AND OBJECTIVES
Telerehabilitation is the remote delivery of rehabilitation services using telecommunication technologies. Its local adoption was catalyzed by the COVID-19 pandemic, prompting the need to assess user acceptance. This study aimed to determine the acceptance of stroke telerehabilitation among patients, carers, and rehabilitation providers in the Department of Physical Medicine and Rehabilitation at St. Luke’s Medical Center – Global City and Quezon City.
METHODSThis descriptive cross-sectional study used purposive sampling to recruit 73 rehabilitation providers and 10 consumers. Data were collected using a self-administered survey based on the Technology Acceptance Model, covering perceived ease of use, usefulness, and behavioral intent. Descriptive and inferential statistics were used for analysis.
RESULTSMost providers (94.4%) were familiar with telerehabilitation, while only half of the consumers were aware of it. Acceptance was moderate among providers (mean score: 35.75 ± 8.67) and high among consumers (mean score: 31.6 ± 7.52). Female providers were less likely to accept telerehabilitation (p=0.049). Consumers identified financial constraints and lack of a companion as key barriers, while providers cited internet issues and technology use. Both groups viewed telerehabilitation positively for teleconsultation, teletherapy, and telemonitoring. Smartphones were the preferred device; Viber and Facebook Messenger were the most commonly chosen platforms.
CONCLUSIONStroke telerehabilitation was moderately to highly accepted by rehabilitation stakeholders in two tertiary private hospitals in Manila. Findings may guide institutional planning for telerehabilitation services. Training, infrastructure support, and awareness campaigns can help address implementation barriers.
Human ; Male ; Female ; Adult: 25-44 Yrs Old ; Middle Aged: 45-64 Yrs Old ; Remote Consultation ; Physical And Rehabilitation Medicine ; Tertiary Care Centers ; Telecommunications ; Telerehabilitation ; Cross-sectional Studies ; Technology ; Stroke ; Covid-19
2.The acceptance of stroke telerehabilitation among rehabilitation providers and consumers in two tertiary hospitals in the Philippines.
Francis Exequiel M. LAXAMANA ; Marvin Louie S. IGNACIO ; Reynaldo R. REY-MATIAS ; Carl Froilan D. LEOCHICO
Acta Medica Philippina 2026;60(8):37-50
BACKGROUND AND OBJECTIVES
Telerehabilitation is the remote delivery of rehabilitation services using telecommunication technologies. Its local adoption was catalyzed by the COVID-19 pandemic, prompting the need to assess user acceptance. This study aimed to determine the acceptance of stroke telerehabilitation among patients, carers, and rehabilitation providers in the Department of Physical Medicine and Rehabilitation at St. Luke’s Medical Center – Global City and Quezon City.
METHODSThis descriptive cross-sectional study used purposive sampling to recruit 73 rehabilitation providers and 10 consumers. Data were collected using a self-administered survey based on the Technology Acceptance Model, covering perceived ease of use, usefulness, and behavioral intent. Descriptive and inferential statistics were used for analysis.
RESULTSMost providers (94.4%) were familiar with telerehabilitation, while only half of the consumers were aware of it. Acceptance was moderate among providers (mean score: 35.75 ± 8.67) and high among consumers (mean score: 31.6 ± 7.52). Female providers were less likely to accept telerehabilitation (p=0.049). Consumers identified financial constraints and lack of a companion as key barriers, while providers cited internet issues and technology use. Both groups viewed telerehabilitation positively for teleconsultation, teletherapy, and telemonitoring. Smartphones were the preferred device; Viber and Facebook Messenger were the most commonly chosen platforms.
CONCLUSIONStroke telerehabilitation was moderately to highly accepted by rehabilitation stakeholders in two tertiary private hospitals in Manila. Findings may guide institutional planning for telerehabilitation services. Training, infrastructure support, and awareness campaigns can help address implementation barriers.
Human ; Male ; Female ; Adult: 25-44 Yrs Old ; Middle Aged: 45-64 Yrs Old ; Remote Consultation ; Physical And Rehabilitation Medicine ; Tertiary Care Centers ; Telecommunications ; Telerehabilitation ; Cross-sectional Studies ; Technology ; Stroke ; Covid-19
3.Occupational burnout among Filipino radiographers in non-traditional practice settings.
Mark M. Alipio ; Grace Meroflor A. Lantajo ; Joseph Dave M. Pregoner
Acta Medica Philippina 2026;60(7):51-57
BACKGROUND
Occupational burnout is a growing concern in healthcare, which affects professionals across various disciplines. Radiographers working in non-traditional practice settings may face unique stressors that contribute to burnout, yet this population remains understudied, particularly in the Philippines.
OBJECTIVESThis study aimed to (1) assess and compare burnout levels among Filipino radiographers in non-traditional roles, (2) investigate the relationship between demographic variables and burnout, and (3) assess burnout severity by imaging role.
METHODSA cross-sectional, quantitative survey design was employed. Participants (n = 188) completed an online survey including demographic questions and the Maslach Burnout Inventory (MBI). Data analysis was performed using SPSS 23. Non-parametric tests were used to assess relationships between demographic variables and MBI scores.
RESULTSSignificant differences in burnout scores were found across imaging roles (p = .000). Mobile imaging professionals reported the highest emotional exhaustion (M = 48.4, SD = 4.7) and depersonalization (M = 21.5, SD = 4.7), and the lowest personal accomplishment (M = 18.1, SD = 7.2). Forensic imaging professionals reported the lowest overall burnout (M = 58.9, SD = 13.8) and depersonalization (M = 7.7, SD = 4.3), and the highest personal accomplishment (M = 29.4, SD = 8.3). Sex differences were observed for depersonalization (p = .045), with males scoring higher. Participants with graduate degrees reported lower personal accomplishment (p = .036). Severe burnout was the dominant category, especially in mobile, military, and veterinary imaging.
CONCLUSIONBurnout levels vary significantly among Filipino radiographers in non-traditional roles, with mobile imaging professionals at particularly high risk. These findings highlight the need for targeted interventions to mitigate burnout and promote wellbeing in this population.
Human ; Burnout, Professional ; Technology, Radiologic ; Philippines ; Cross-sectional Studies
4.Bridging stroke care through technology: Knowledge, attitudes, and practices of barangay health workers in Quezon City on a telestroke network.
Gerard Vincent A. Aguas ; Dan Neftali A. Juangco ; Deborah A. Bernardo
Philippine Journal of Neurology 2026;29(1):36-43
BACKGROUND
Stroke is a leading cause of morbidity and mortality in the Philippines. Telestroke systems have been introduced to improve timely recognition and referral; however, their effectiveness depends on utilization at the community level.
OBJECTIVETo assess stroke and telestroke knowledge, attitudes, practices, and barriers among barangay health workers (BHWs), and to determine factors associated with telestroke utilization.
METHODSA cross-sectional study was conducted among 202 BHWs. Data were collected using a structured questionnaire assessing knowledge, attitudes, practices, and perceived barriers. Descriptive statistics were used to summarize responses. Associations between variables were analyzed using appropriate statistical tests, with significance set at p < 0.05.
RESULTSRespondents had high stroke knowledge (75.5%, SD = 17.45) and telestroke knowledge (85.5%, SD = 18.82), as well as favorable attitudes (mean = 4.37). However, only 31.1% reported telestroke utilization. The most commonly reported barriers were lack of training (61.4%) and poor internet connectivity (15.8%). Telestroke familiarity was significantly associated with higher knowledge (p = 0.005) and more favorable attitudes (p = 0.001). Stroke-related training (p = 0.001) and years of experience (p = 0.001) were significantly associated with higher utilization.
CONCLUSIONDespite high knowledge and favorable attitudes, telestroke utilization among BHWs remains low. Training, familiarity, and infrastructure appear to play key roles in bridging the gap between knowledge and practice. Strengthening these factors may improve the effectiveness of community-based telestroke systems.
Human ; Occupational Groups ; Knowledge ; Attitude ; Stroke ; Technology
5.Design of a novel, modular, mouth retractor: A concept testing study
Miguel Sandino O. Aljibe ; Airene Maria C. Apacible ; Philip B. Fullante
Acta Medica Philippina 2025;59(Early Access 2025):1-10
BACKGROUND AND OBJECTIVES
Mouth retractors are essential in ensuring efficient yet safe exposure of the oral cavity and oropharynx. However, when applied improperly or haphazardly, retractors can cause tissue injuries and compromise patient safety. In addition, there are gaps in the usability of existing designs. This study aimed to identify the issues encountered by otorhinolaryngology surgeons in the use of commercially available mouth retractors, design and fabricate an improved retractor, and explore the use of additive manufacturing (popularly known as 3D printing) for retractor prototyping.
METHODSThe study used the United States Food and Drug Administration (US FDA) Design Control as its framework. End-user requirements from otorhinolaryngologists were collected through key informant interviews. Results were organized into a Design Input template which was used to guide the design and development process. Prototype designs were iteratively created using computer-aided design software and 3D printing. Once design specifications were satisfied, a beta prototype was fabricated and given to another cohort of otorhinolaryngologists. The participants assessed the usability of the beta prototype. System Usability Scale (SUS) was used to quantify participant's feedback.
RESULTSFive designs were created in the course of the study. The final prototype was fabricated using a Stereolithography (SLA) 3D printer. Several features were developed to address user requirements. The primary modification was to make the retractor modular to facilitate easier and shorter mounting and assembly. Gingival injury was addressed with the replacement of the maxillary alveolus hook with support bars. Five participants evaluated the beta prototype which received a mean SUS score of 75, well above the 50th percentile threshold.
CONCLUSIONThis study demonstrates the applicability of the US FDA Design Control Process in the local setting to improve the mouth retractor design. Clinical and ergonomic issues were identified and design solutions were proposed and some have been implemented in a low-fidelity prototype. Results of the small-scale usability test suggest that the present form factor can be the basis for further iterations. Future studies can implement the proposed features to address other clinical and ergonomic needs.
Human ; 3d Printing ; Printing, Three-dimensional ; Devices, Medical ; Equipment And Supplies
6.Osteomodulin modulates the inflammatory responses via the interleukin-1 receptor 1/nuclear factor-κB signaling pathway in dental pulpitis.
Yueyi YANG ; Xuchen HU ; Meiling JING ; Xiaohan ZHU ; Xiaoyu LIU ; Wenduo TAN ; Zhanyi CHEN ; Chenguang NIU ; Zhengwei HUANG
International Journal of Oral Science 2025;17(1):41-41
Pulpitis is a common infective oral disease in clinical situations. The regulatory mechanisms of immune defense in pulpitis are still being investigated. Osteomodulin (OMD) is a small leucine-rich proteoglycan family member distributed in bones and teeth. It is a bioactive protein that promotes osteogenesis and suppresses the apoptosis of human dental pulp stem cells (hDPSCs). In this study, the role of OMD in pulpitis and the OMD-induced regulatory mechanism were investigated. The OMD expression in normal and inflamed human pulp tissues was detected via immunofluorescence staining. Intriguingly, the OMD expression decreased in the inflammatory infiltration area of pulpitis specimens. The cellular experiments demonstrated that recombined human OMD could resist the detrimental effects of lipopolysaccharide (LPS)-induced inflammation. A conditional Omd knockout mouse model with pulpal inflammation was established. LPS-induced inflammatory impairment significantly increased in conditional Omd knockout mice, whereas OMD administration exhibited a protective effect against pulpitis. Mechanistically, the transcriptome alterations of OMD overexpression showed significant enrichment in the nuclear factor-κB (NF-κB) signaling pathway. Interleukin-1 receptor 1 (IL1R1), a vital membrane receptor activating the NF-κB pathway, was significantly downregulated in OMD-overexpressing hDPSCs. Additionally, the interaction between OMD and IL1R1 was verified using co-immunoprecipitation and molecular docking. In vivo, excessive pulpal inflammation in Omd-deficient mice was rescued using an IL1R antagonist. Overall, OMD played a protective role in the inflammatory response via the IL1R1/NF-κB signaling pathway. OMD may optimize the immunomodulatory functions of hDPSCs and can be used for regenerative endodontics.
Pulpitis/metabolism*
;
NF-kappa B/metabolism*
;
Animals
;
Signal Transduction
;
Humans
;
Mice
;
Mice, Knockout
;
Dental Pulp/metabolism*
;
Disease Models, Animal
;
Lipopolysaccharides
7.Expert consensus on digital restoration of complete dentures.
Yue FENG ; Zhihong FENG ; Jing LI ; Jihua CHEN ; Haiyang YU ; Xinquan JIANG ; Yongsheng ZHOU ; Yumei ZHANG ; Cui HUANG ; Baiping FU ; Yan WANG ; Hui CHENG ; Jianfeng MA ; Qingsong JIANG ; Hongbing LIAO ; Chufan MA ; Weicai LIU ; Guofeng WU ; Sheng YANG ; Zhe WU ; Shizhu BAI ; Ming FANG ; Yan DONG ; Jiang WU ; Lin NIU ; Ling ZHANG ; Fu WANG ; Lina NIU
International Journal of Oral Science 2025;17(1):58-58
Digital technologies have become an integral part of complete denture restoration. With advancement in computer-aided design and computer-aided manufacturing (CAD/CAM), tools such as intraoral scanning, facial scanning, 3D printing, and numerical control machining are reshaping the workflow of complete denture restoration. Unlike conventional methods that rely heavily on clinical experience and manual techniques, digital technologies offer greater precision, predictability, and efficacy. They also streamline the process by reducing the number of patient visits and improving overall comfort. Despite these improvements, the clinical application of digital complete denture restoration still faces challenges that require further standardization. The major issues include appropriate case selection, establishing consistent digital workflows, and evaluating long-term outcomes. To address these challenges and provide clinical guidance for practitioners, this expert consensus outlines the principles, advantages, and limitations of digital complete denture technology. The aim of this review was to offer practical recommendations on indications, clinical procedures and precautions, evaluation metrics, and outcome assessment to support digital restoration of complete denture in clinical practice.
Humans
;
Denture, Complete
;
Computer-Aided Design
;
Denture Design/methods*
;
Consensus
;
Printing, Three-Dimensional
8.Thymosin α1 alleviates pulpitis by inhibiting ferroptosis of dental pulp cells.
Jie WU ; Qimei GONG ; Wenxuan LIU ; Aijia CHEN ; Zekai LIAO ; Yihua HUANG ; Wenkai JIANG ; Zhongchun TONG
International Journal of Oral Science 2025;17(1):68-68
Tooth pulpitis is a prevalent oral disorder. Understanding the underlying mechanisms of pulpitis and developing effective treatment strategies hold great significance. Ferroptosis has recently emerged as a new form of cell death, but the role of ferroptosis in pulpitis remains largely unknown. In our study, single-cell RNA sequencing (scRNA-seq) was used to identify cellular heterogeneity between 3 pulpitis tissue and 3 healthy pulp tissue, and explored ferroptosis occurrence in pulpitis tissue and inflamed dental pulp cells (DPCs). In scRNA-seq, 40 231 cells (Pulpitis: 17 814; Healthy pulp: 22 417) were captured, and visualized into 12 distinct cell clusters. Differentially expressed ferroptosis-related genes (DE-FRGs) were almost presented in each cluster in pulpitis vs healthy pulp. ROS and Fe2+ levels significantly rose, and immunohistochemistry showed low expression of GPX4 and high expression of PTGS2 in pulpitis. In LPS-stimulated DPCs, thymosin α1 increased the expression of GPX4 and FTL, and decreased expression of TNF-α, IL-1β, IL-6, and Fe2+ levels. In rat pulpitis models, both prothymosin α (PTMA, precursor of thymosin α1) gelatin sponge placed at the hole of pulp (LPS-P(gs)) and PTMA injection in pulp (LPS-P(i)) significantly reduced infiltration of inflammatory cells and expression of PTGS2, and increased the expression of GPX4. In RNA sequencing, the expression of DE-FRGs were reversed when thymosin α1 were added in LPS-stimulated DPCs. Collectively, single-cell atlas reveals cellular heterogeneity between pulpitis and healthy pulp, and ferroptosis occurrence in pulpitis. Thymosin α1 may reduce ferroptosis in DPCs to alleviate pulpitis and thus potentially has the ability to treat pulpitis.
Ferroptosis/drug effects*
;
Dental Pulp/drug effects*
;
Animals
;
Pulpitis/pathology*
;
Rats
;
Thymalfasin/pharmacology*
;
Humans
;
Male
;
Thymosin/pharmacology*
;
Disease Models, Animal
;
Rats, Sprague-Dawley
9.Effect of slurry proportion on the microstructure and properties of dental lithium disilicate ceramics manufactured through 3D printing.
Baoxin LIN ; Xiaoxuan CHEN ; Ruyi LI ; Qianbing WAN ; Xibo PEI
West China Journal of Stomatology 2025;43(2):175-182
OBJECTIVES:
This study aims to use 3D prin-ting technology based on the principle of stereo lithography apparatus (SLA) to shape dental lithium disilicate ceramics and study the effects of different slurry proportions on the microstructure and properties of heat-treated samples.
METHODS:
The experimental group comprised lithium disilicate ceramics manufactured through SLA 3D printing, and the control group comprised lithium disilicate ceramics (IPS e.max CAD) fabricated through commercial milling. An array of different particle sizes of lithium disilicate ceramic powder materials (nano and micron) was selected for mixing with photocurable acrylate resin. The proportion of experimental raw materials was adjusted to prepare five groups of ceramic slurries for 3D printing (Groups S1-S5) on the basis of rheological properties, stability, and other factors. Printing, debonding, and sintering were conducted on the experimental group with the optimal ratio, followed by measurements of microstructure, crystallographic information, shrinkage, and mechanical properties.
RESULTS:
Five groups of lithium disilicate ceramic slurries were prepared, of which two groups with high solid content (75%) (Groups S2 and S3) were selected for 3D printing. X-ray diffraction and scanning electron microscopy results showed that lithium disilicate was the main crystalline phase in Groups S2 and S3, and its microstructure was slender, uniform, and compact. The average grain sizes of Groups S2 and S3 were (559.79±84.58) nm and (388.26±61.49) nm, respectively (P<0.05). Energy spectroscopy revealed that the samples in the two groups contained a high proportion of Si and O elements. After heat treatment, the shrinkage rate of the two groups of ceramic samples was 18.00%-20.71%. Test results revealed no statistical difference in all mechanical properties between Groups S2 and S3 (P>0.05). The flexural strengths of Groups S2 and S3 were (231.79±21.71) MPa and (214.86±46.64) MPa, respectively, which were lower than that of the IPS e.max CAD group (P<0.05). The elasticity modulus of Groups S2 and S3 were (87.40±12.99) GPa and (92.87±19.76) GPa, respectively, which did not significantly differ from that of the IPS e.max CAD group (P>0.05). The Vickers hardness values of Groups S2 and S3 were (6.53±0.19) GPa and (6.25±0.12) GPa, respectively, which were higher than that of the IPS e.max CAD group (P<0.05). The fracture toughness values of Groups S2 and S3 were (1.57±0.28) MPa·m0.5 and (1.38±0.17) MPa·m0.5, respectively, which did not significantly differ from that of the IPS e.max CAD group (P>0.05).
CONCLUSIONS
The combination of lithium disilicate ceramic powders with different particle sizes can yield a slurry with high solid content (75%) and suitable viscosity and stability. The dental lithium disilicate ceramic material is successfully prepared by using 3D printing technology. The 3D-printed samples show a small shrinkage rate after heat treatment. Their microstructure conforms to the crystal phase of lithium disilicate ceramics, and their mechanical properties are close to those of milled lithium disilicate ceramics.
Printing, Three-Dimensional
;
Dental Porcelain/chemistry*
;
Ceramics/chemistry*
;
Materials Testing
;
Particle Size
10.Evaluation of the function and activity of masticatory muscles using a self-developed wireless surface electromyography system.
Wenbo LI ; Yujia ZHU ; Qingzhao QIN ; Shenyao SHAN ; Zixiang GAO ; Aonan WEN ; Yong WANG ; Yijiao ZHAO
West China Journal of Stomatology 2025;43(3):346-353
OBJECTIVES:
This study aimed to evaluate the repeatability and reliability of a self-developed domestic wireless surface electromyography (sEMG) system (Oralmetry) in assessing the activity of the temporalis and masseter muscles to provide theoretical support for its clinical application.
METHODS:
Twenty-two volunteers were recruited. Through multiple repeated measurements, the sEMG signals of bilateral anterior temporalis and masseter muscles during maximum voluntary clenching were collected using the self-developed sEMG device, Oralmetry, and two commercial sEMG devices (Zebris and Teethan), filtered, screened, and standardized. Seven sEMG indicators for assessing masticatory muscle function were calculated. The intraclass correlation coefficient (ICC) was used to evaluate the repeatability of the measurements from the three sEMG devices, and statistical analysis was conducted to compare the consistency of the seven sEMG indicators obtained from the devices.
RESULTS:
Among the 22 participants, the ICC values of the repeated measurements from the three sEMG devices ranged from 0.88 to 0.99. The measurements of three sEMG indicators (antero-posterior coeffificient, percentage overlapping coeffificient_MM, and percentage overlapping coeffificient_TA) obtained by Zebris were significantly different from those obtained by Oralmetry and Teethan (P<0.05). No significant differences in the measurements of the seven sEMG indicators were found between Oralmetry and Teethan.
CONCLUSIONS
Oralmetry and the two commercial sEMG devices demonstrated good repeatability in capturing sEMG indicators for evaluating masticatory muscle function. In particular, Oralmetry showed the highest ICC values. All three devices also exhibited good consistency in measuring sEMG indicators, and a high agreement was observed between the two wireless sEMG devices (Oralmetry and Teethan). These findings provide theoretical support for the clinical application of Oralmetry.
Humans
;
Electromyography/methods*
;
Masseter Muscle/physiology*
;
Masticatory Muscles/physiology*
;
Wireless Technology
;
Reproducibility of Results
;
Temporal Muscle/physiology*
;
Male
;
Adult
;
Female
;
Young Adult


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