1.A Case of Lentigo Maligna Melanoma.
Hwan Pyo JEON ; Jae Il YOUN ; Yoo Shin LEE ; Gwang Yeol JOH
Korean Journal of Dermatology 1989;27(1):99-103
Herein we report a case of lentigo maligna that evolved into lentigo maligna melanoma. Fifteen years ago, the patient developed a pigmented lesion on the right cheek. The lesion progressed slowly, and 2 months ago, a black nodular lesion was developed in the periphery of the pigmented lesion. Histopathologic examination of the lesions revealed findings consistent with lentigo maligna and lentigo maligna melanorna. She had been performed wide excision and cheek flap for reconstruction.
Cheek
;
Humans
;
Hutchinson's Melanotic Freckle*
;
Lentigo*
;
Melanoma*
2.Amelanotic Melanoma Mimicking Eccrine Poroma.
Jun Gyu SONG ; Jun Gyu SONG ; Moo Kyu SUH ; Jong Im LEE ; Seok Jong LEE
Korean Journal of Dermatology 2016;54(4):314-316
No abstract available.
Melanoma, Amelanotic*
;
Poroma*
3.An Ulcerative Amelanotic Melanoma on the Heel.
So Young YOON ; Young Woon PARK ; Eun Jee KIM ; Hyun Sun PARK ; Hyun Sun YOON ; Soyun CHO
Korean Journal of Dermatology 2013;51(12):995-996
No abstract available.
Heel*
;
Melanoma, Amelanotic*
;
Ulcer*
4.Cytologic features of primary amelanotic melanoma of the vagina: a case report.
Sung Ran HONG ; Hy Sook KIM ; Chong Tack PARK
Korean Journal of Cytopathology 1993;4(1):41-44
No abstract available.
Melanoma, Amelanotic*
;
Vagina*
5.A Case of Lentigo Maligna Melanoma Treated with Mohs Micrographic Surgery.
Bon Seok KU ; Oh Eon KWON ; Dae Cheol KIM ; Keun Cheol LEE ; Chae Wook LEE ; Ki Ho KIM
Korean Journal of Dermatology 2006;44(4):457-461
Lentigo maligna melanoma and lentigo maligna are typically located on photo-exposed sites such as the head and neck, with the cheek being the most common site. Since lentigo maligna melanoma and lentigo maligna are found predominantly on such cosmetically-sensitive areas, it is critical to determine the exact histologic margin for maximal sparing of tissue and complete extirpation of the tumor. Since Mohs micrographic surgery has been recommended for tumors on cosmetically-sensitive locations where the tumor margin is indistinct, it appears to be a reasonable treatment modality for this type of tumor. We describe a case of lentigo maligna melanoma on the cheek, which was resected with Mohs micrographic surgery.
Cheek
;
Head
;
Hutchinson's Melanotic Freckle*
;
Lentigo*
;
Melanoma*
;
Mohs Surgery*
;
Neck
6.A Case of Desmoplastic Malignant Melanoma.
Joo Hyun SHIM ; Seong Jun SEO ; Kye Yong SONG ; Chang Kwun HONG
Annals of Dermatology 2001;13(4):250-253
Desmoplastic malignant melanoma (DMM) is an uncommon variant of malignant melanoma featuring a proliferation of spindle cells with pronounced desmopaasia. DMM commonly occurs on the sun-damaged skin such as head and neck in older persons, and it can be associated with lentigo maligna. We report an unusual case of desmoplastic malignant melanoma that developed de novo on the trunk in a young patient.
Head
;
Humans
;
Hutchinson's Melanotic Freckle
;
Melanoma*
;
Neck
;
Skin
7.Immunohistochemical Study of Malignant Melanoma with HMB - 45 Monoclonal Antibody and Anti S - 100 Protein Antibody.
Kyu Han KIM ; Kwang Hyun CHO ; Eui Keun HAM
Korean Journal of Dermatology 1990;28(6):730-736
We evaluated the characteristics of HMB-45 monoclonal antibody(MoAb) and compared it with a polyclonal anti-S-100 antibody in immunohistochemical staining of 22 primary melanomas of the skin ; 13 acral lentiginous melanomas(ALM), 3 superficial spreading melanomas(SSM), 4 lentigo maligna melanomas(LMM), 3 nodular melanomas(NMM). All speimens were formalin-fixed and paraffin-embedded, and were studied with the avidin-biotin-peroxidase complex technique. The results can be summarized as follows : l. In all tissue specimens, all or some of the melanoma cells in the dermis reacted with HMB-45 MoAb and anti-S-100 protein. 2. HMB-45 MoAb is more sensitive in detecting malignant melanoma cell heterogeneity t,han anti-S-100 protein. 3. Melanoma cells within the epidermis in 6 of 12 ALMs and 3 of 4 LMMs did not react with anti-S-100 antibody, whereas most melanoma cells within epidermis of 12 ALMs and 4 LMMs reacted with HMB-45 monoclonal antibody. These results indicated that immunohistochemical staining with HMB-45 MoAb and anti-S-100 protein is very useful in the study of biologic behavior of malignant, melanoma.
Dermis
;
Epidermis
;
Hutchinson's Melanotic Freckle
;
Melanoma*
;
Population Characteristics
;
Skin
8.Immunohistochemistry: sole tool in diagnosing a rare case of primary vaginal amelanotic melanoma.
Obstetrics & Gynecology Science 2018;61(6):698-701
We report a rare case of vaginal amelanotic melanoma. Malignant melanomas are cutaneous and extracutaneous tumors that arise from embryological remnants of neural crest cells/melanocytes. Amelanotic melanomas at such rare locations can be misdiagnosed both clinically and radiologically. Therefore, histopathological examination and immunohistochemistry are mandatory for the diagnosis of these tumors. We diagnosed this case using histopathology and confirmed the diagnosis based on the presence of immunohistochemical markers human melanoma black 45 (HMB45) and S-100.
Diagnosis
;
Humans
;
Immunohistochemistry*
;
Melanoma
;
Melanoma, Amelanotic*
;
Neural Crest
;
Vagina
9.A Case of Lentigo Maligna Developed on the Sole.
Kyung YOO ; Jee Yoon HAN ; Jeong Rae KIM
Korean Journal of Dermatology 1983;21(2):201-205
Lentigo maligna, a precancerous tumor arising from abnormal melanocytes, is a chronic, slowly progressive, pigmented lesion with a range of colors from pale tan to black and an irregular shape, The commonest location of lentigo maligna is the face during the sixth and seventh decades of life. Less frequently, the lesion occurs on an extrafacial area such as the hand or lower leg. In the late stage, lentigo maligna transforms into invasive malignant melanoma. A 50-year-old male patient had a well-defined, black pigmented patch on the right sole for 30 years. The histopathologic examination revealed numerous vacuolated melanocytes clusters at the dermo-epidermal junction with invasion of the epidermis. There was no evidence of dermal invasion by atypical melanocytes.
Epidermis
;
Hand
;
Humans
;
Hutchinson's Melanotic Freckle*
;
Leg
;
Lentigo*
;
Male
;
Melanocytes
;
Melanoma
;
Middle Aged
;
Triacetoneamine-N-Oxyl
10.A Case of Lentigo Maligna Melanoma.
Jee Youn WON ; Young Min JEON ; Eun Sup SONG
Korean Journal of Dermatology 2000;38(10):1362-1365
Lentigo maligna melanoma(LMM) is the least common type of melanoma and most commonly affects the sun-exposed skin of the elderly. We herein report a case of LMM evolved from lentigo maligna(LM). A 71-year-old female presented with a longstanding irregular brown patch containing two black papules on the left cheek which developed 8 months ago. Histopathologic findings were consistent with LM and LMM. We performed a wide excision and dufourmental flap for reconstruction with no recurrence for 30 months. Sun exposure has been known as the most important etiologic factor for the development of malignant melanoma including LMM and the incidence has an increasing tendency. Thus, skin biopsy is recommended in the evaluation of a longstanding irregular brown patch on the face to prevent LMM.
Aged
;
Biopsy
;
Cheek
;
Female
;
Humans
;
Hutchinson's Melanotic Freckle*
;
Incidence
;
Lentigo*
;
Melanoma*
;
Recurrence
;
Skin
;
Solar System