1.Risk and protective factors associated with adolescent depression in Singapore: a systematic review.
Wei Sheng GOH ; Jun Hao Norman TAN ; Yang LUO ; Sok Hui NG ; Mohamed Sufyan Bin Mohamed SULAIMAN ; John Chee Meng WONG ; Victor Weng Keong LOH
Singapore medical journal 2025;66(1):2-14
INTRODUCTION:
Adolescent depression is prevalent, and teen suicide rates are on the rise locally. A systemic review to understand associated risk and protective factors is important to strengthen measures for the prevention and early detection of adolescent depression and suicide in Singapore. This systematic review aims to identify the factors associated with adolescent depression in Singapore.
METHODS:
A systematic search on the following databases was performed on 21 May 2020: PubMed, EMBASE and PsycINFO. Full texts were reviewed for eligibility, and the included studies were appraised for quality using the Newcastle Ottawa Scale. Narrative synthesis of the finalised articles was performed through thematic analysis.
RESULTS:
In total, eight studies were included in this review. The four factors associated with adolescent depression identified were: (1) sociodemographic factors (gender, ethnicity); (2) psychological factors, including childhood maltreatment exposure and psychological constructs (hope, optimism); (3) coexisting chronic medical conditions (asthma); and (4) lifestyle factors (sleep inadequacy, excessive internet use and pathological gaming).
CONCLUSION
The identified factors were largely similar to those reported in the global literature, except for sleep inadequacy along with conspicuously absent factors such as academic stress and strict parenting, which should prompt further research in these areas. Further research should focus on current and prospective interventions to improve mental health literacy, targeting sleep duration, internet use and gaming, and mitigating the risk of depression in patients with chronic disease in the primary care and community setting.
Humans
;
Singapore/epidemiology*
;
Adolescent
;
Risk Factors
;
Depression/etiology*
;
Protective Factors
;
Male
;
Female
;
Life Style
;
Suicide
2.Role of lifestyle factors on the development and long-term prognosis of pneumonia and cardiovascular disease in the Chinese population.
Yizhen HU ; Qiufen SUN ; Yuting HAN ; Canqing YU ; Yu GUO ; Dianjianyi SUN ; Yuanjie PANG ; Pei PEI ; Ling YANG ; Yiping CHEN ; Huaidong DU ; Mengwei WANG ; Rebecca STEVENS ; Junshi CHEN ; Zhengming CHEN ; Liming LI ; Jun LV
Chinese Medical Journal 2025;138(12):1456-1464
BACKGROUND:
Whether adherence to a healthy lifestyle is associated with a lower risk of developing pneumonia and a better long-term prognosis remains unclear. This study aimed to investigate associations of individual and combined lifestyle factors (LFs) with the incidence risk and long-term prognosis of pneumonia hospitalization.
METHODS:
Using data from the China Kadoorie Biobank study, we used the multistate models to investigate the role of five high-risk LFs, including smoking, excessive alcohol drinking, unhealthy dietary habits, physical inactivity, and unhealthy body shape, alone or in combination in the transitions from a generally healthy state at baseline to pneumonia hospitalization or cardiovascular disease (CVD, regarded as a reference outcome), and subsequently to mortality.
RESULTS:
Most of the five high-risk LFs were associated with increased risks of transitions from baseline to pneumonia and from pneumonia to death, but with different risk estimates. The greater the number of high-risk LFs, the higher the risk of developing pneumonia and long-term mortality risk after pneumonia, with the strength of associations comparable to that of LFs and CVD. Compared to participants with 0-1 high-risk LF, the adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for transitions from baseline to pneumonia and from pneumonia to death in those with five high-risk LFs were 1.43 (1.28-1.60) and 1.98 (1.61-2.42), respectively. Correspondingly, the respective HRs (95% CIs) for transitions from baseline to CVD and from CVD to death were 2.00 (1.89-2.11) and 1.44 (1.30-1.59), respectively. The risk estimates changed slightly when further adjusting for the presence of major chronic diseases.
CONCLUSION
In this Chinese population, unhealthy LFs were associated with an increased incidence and long-term mortality risk of pneumonia.
Adult
;
Aged
;
Female
;
Humans
;
Male
;
Middle Aged
;
Cardiovascular Diseases/etiology*
;
China/epidemiology*
;
Life Style
;
Pneumonia/etiology*
;
Prognosis
;
Risk Factors
;
Smoking
3.Complex associations among modifiable determinants of circadian syndrome among employed people in southwestern China.
Shujuan YANG ; Peng JIA ; Lei ZHANG ; Yuchen LI ; Peng YU ; Jiqi YANG ; Sihan WANG ; Honglian ZENG ; Bo YANG ; Bin YU
Chinese Medical Journal 2025;138(21):2804-2812
BACKGROUND:
Circadian syndrome (CircS) may be closely linked to lifestyle, psychological, and occupational factors, but evidence is lacking. This study aimed to explore complex associations between lifestyle, psychological and occupational factors and CircS among employed people in southwestern China.
METHODS:
In this study, network analysis was used to identify complex associations between lifestyle, psychological and occupational factors and CircS in employed people from the Chinese Cohort of Working Adults (CCWA). The centrality of each variable was estimated by strength centrality index, which was calculated by the sum of edge weights connected to the variable. Bridge in the network was identified as the variables in the top 80 th percentile of overall bridge strength, which was defined as the most strongly connected variables across lifestyle, psychological and occupational factors and CircS. The differences were assessed in network structures between subgroups divided by the median score of the variable with the strongest bridge strengthen.
RESULTS:
Among 31,105 participants from CCWA, 5213 (16.76%) had CircS. In the constructed network, anxiety (edge weights: 0.28), smoking (edge weights: 0.15), drinking (edge weights: 0.10), perceived noise at work (edge weights: 0.08), and implicit health attitude (edge weights: -0.02) were directly related to CircS, with 83.31% of the variance for CircS explained by these neighboring factors. Anxiety was the most central variable (strength centrality: 1.20) in the network and the strongest bridge (bridge strength: 0.84) connecting all domains of variables. A stronger association between anxiety and CircS was observed in the network of participants with more severe anxiety (edge weight: 0.23) than those with less severe anxiety (edge weight: 0.03).
CONCLUSION
Anxiety had the strongest association with CircS and was the central factor with the highest strength centrality, also the bridge with the highest bridge strength in the network.
Humans
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Male
;
Female
;
Adult
;
China
;
Middle Aged
;
Life Style
;
Chronobiology Disorders/epidemiology*
4.Role of traditional Chinese medicine concepts in the prevention of childhood caries.
Jin SUN ; Jiahui HE ; Qian CHEN ; Wei LUO
West China Journal of Stomatology 2025;43(4):486-492
The high prevalence of childhood caries poses a considerable threat to children's overall health. Traditional Chinese medicine (TCM) concepts offers a distinctive and valuable perspective on caries prevention. This study explores TCM's conceptualization of dental caries in relation to the physiological characteristics of children and proposes targeted preventive strategies, including holistic care, dietary regulation, and lifestyle modification. In addition, the study highlights the role of traditional modalities, such as Chinese herbal medicine, acupuncture, moxibustion, and tuina, in caries prevention, while emphasizing the importance of supporting children's mental health. The integration of TCM with modern medical practices holds promise for advancing research into the prevention and treatment of caries. Furthermore, promoting the overall improvement of children's health.
Dental Caries/prevention & control*
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Humans
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Medicine, Chinese Traditional
;
Child
;
Acupuncture Therapy
;
Moxibustion
;
Life Style
;
Drugs, Chinese Herbal/therapeutic use*
5.Extent of health-promoting lifestyle among student nurses in private schools in Baguio City: A quantitative descriptive research study.
Florence L. PULIDO ; Gemson Yahweh S. AQUINO ; Aira Marie PARUNGAO ; Kyle Cristel B. BALOALOA ; Trinna Camille B. ABRIGO ; Clarissa V. CAJAYON ; Irish Justine J. GONZALES ; Rhea Kathleen A. MEJIA ; Vincent Kyle E. DE CASTRO ; Rolando C. ESGUERRA ; Sofia Rafaela D. VELARDE
Acta Medica Philippina 2025;59(19):30-42
INTRODUCTION
style="text-align: justify;" data-mce-style="text-align: justify;">The Bachelor of Science in Nursing (BSN) program spans four years and includes general education and professional courses. Student nurses attend lecture hours, clinical duties, and related learning experiences that might be affecting their time in attending to a healthy lifestyle. Health-promoting lifestyle is a multi-dimensional pattern of activities and perceptions that begins with self-motivation and assists in promoting self-improvement and health. The domains of health-promoting lifestyle are essential factors to further improve their way of dealing with daily challenges. Multiple factors can also influence student nurses’ lifestyles, including their separation from family, busy schedules, and dietary choices. A study highlights various factors affecting student nurses' lifestyles, underscoring the need for tailored health promotion strategies and curriculum enhancements. Research into these domains can better equip future healthcare leaders. Gender, year level, and living arrangements influence student nurses' lifestyles, prompting researchers to investigate the extent of health-promoting lifestyles among them and differences based on these factors. By addressing these domains and conducting further research, nursing education and practice can better prepare future healthcare leaders to promote health and lifestyle effectively within their communities.
OBJECTIVESstyle="text-align: justify;" data-mce-style="text-align: justify;">To determine the extent of health-promoting lifestyle among student nurses and identify the significant differences according to gender, year level, and living arrangement.
METHODSstyle="text-align: justify;" data-mce-style="text-align: justify;">A quantitative, descriptive research design was used with 360 respondents, employing Yamane’s formula and quota sampling. The study adopted the Health-Promoting Lifestyle II questionnaire with a validity of 0.962.
RESULTSstyle="text-align: justify;" data-mce-style="text-align: justify;">Student nurses often engage in health promoting behaviors (mean=2.56). Male student nurses reported higher scores in health responsibility, physical activity, spiritual growth, and stress management compared to female students (p=0.40). Level IV students engaged in health-promoting activities more frequently than Level I students (p=0.74). Living arrangements did not significantly impact health-promoting lifestyles (p=0.99).
CONCLUSIONstyle="text-align: justify;" data-mce-style="text-align: justify;">No significant difference in health-promoting lifestyles among student nurses. Respondents demonstrated the least health-promoting lifestyle behaviors in the domains of health responsibility, nutrition, and physical activity. In contrast, spiritual growth, interpersonal relations, and stress management attained the highest mean scores.
Human ; Physical Activity ; Exercise ; Interpersonal Relations ; Students, Nursing ; Life Style
6.Active video games for weight management in children and adolescents: systematic review and meta-analysis.
Maria Godesa F. REFUERZO ; Michael M. RESURRECCION
The Philippine Children’s Medical Center Journal 2025;21(2):100-116
Aims: We evaluated the efficacy of active video games as weight reduction intervention among obese children and adolescents by synthesizing available published evidence.
Materials and methods: A meta-analysis was performed using nine RCTs based on the PRISMA guidelines. Children less than 18 years of age who are Obese I and Obese II and underwent active video games intervention or standard weight management programs were included. A search was performed in PubMed/MEDLINE, EMBASE, Scopus, Cochrane, and HERDIN databases from inception to September 2024 databases using the MeSH and key words: (“video games” or “digital games” or “console games” or “electronic games”) AND (“weight loss” or BMI or obesity) AND (children OR pediatric OR adolescents) AND (RCT OR trials OR “randomized controlled trial). Pooled mean difference was used to determine effectiveness on reducing weight and BMI.
Results: The pooled mean difference showed significantly lower post-intervention weight (in kg) (MD=-2.97, 95%CI=-5.15 to -0.78, p=0.008) and significantly lower post-intervention BMI z-score (MD=-0.12, 95%CI=-0.13 to -0.10, p<0.000001) on children with AVG intervention. There was also lower post-intervention BMI on children with AVG intervention (MD=-1.27, 95%CI=-2.93 to 0.38). However, the difference was not statistically significant (p=0.13).
Conclusion:Active video games showed a significant benefit in weight reduction among obese children. Usual lifestyle modification interventions may be challenging due to lack of motivation and poor adherence among younger demographics. AVGs present a novel approach by integrating entertainment with physical activity, thereby addressing these barriers.
Human ; Male ; Female ; Infant: 1-23 Months ; Child Preschool: 2-5 Yrs Old ; Child: 6-12 Yrs Old ; Adolescent: 13-18 Yrs Old ; Randomized Controlled Trial ; Adolescent ; Meta-analysis ; Video Games ; Life Style ; Exercise ; Electronics
7.Lifestyle risk profile of an urban community under a community oriented primary care program: A cross-sectional study.
The Filipino Family Physician 2025;63(2):235-245
INTRODUCTION
According to the World Health Organization (2024), 41 million people are killed each year by Noncommunicable diseases (NCDs) which is equivalent to 74% deaths globally and 68.5% in the Philippines NCDs considered as lifestyle related include cardiovascular conditions (hypertension, stroke), diabetes mellitus, lung/chronic respiratory diseases and a range of cancers. Tobacco use, physical inactivity, harmful use of alcohol and unhealthy diet increase the risk of death from noncommunicable diseases. Early identification of individuals who are at risk using lifestyle assessment tools is important in the prevention of these non-communicable diseases.
OBJECTIVEThe aim of this study was to determine the lifestyle risk profile of an urban community under a Community Oriented Primary Care program.
METHODSThis was a cross-sectional survey conducted in an urban community under a Community-Oriented Primary Care program. Using systematic random sampling, one respondent from the included households completed a structured questionnaire on socio-demographic characteristics, physical assessment, and lifestyle behaviors using a validated Lifestyle Medicine Assessment (LMA) tool. The questionnaire was translated into the Hiligaynon dialect and underwent expert review and pilot testing, demonstrating excellent validity and reliability. Data were analyzed using descriptive and inferential statistics, with a significance level set at p < 0.05.
RESULTSEighty-seven among 112 households of the community participated in the study. Demographic profiling revealed that most respondents had above-normal waist-hip ratios, and nearly half had above-normal body mass index (BMI). The overall LMA scores indicated a “Very Good” lifestyle profile (scores 31–40). Among demographic factors, only work status showed a statistically significant association with total LMA scores (p = 0.037). Significant associations were found between specific lifestyle domains and socio-demographic factors. The domain of connectedness was significantly associated with age and educational attainment; nutrition showed significant associations with age, marital status, and income; and substance use was significantly associated with sex and work status.
CONCLUSIONConsidering the influence of Lifestyle Behavior on health, especially that of acquiring non-communicable diseases, using lifestyle assessment tools may aid in the formulation of campaigns, projects targeted on the community’s problem. Like in every Family and Community Medicine Residency Programs, COPC programs is one way of using the data gathered on lifestyle behavior in the community.
Human ; Lifestyle Behavior ; Life Style ; Noncommunicable Diseases
8.A 10-year longitudinal analysis of the impact of demographic, lifestyle, and medical factors on semen qualities in men in a city in the midwestern region of the United States of America.
Malik SCOTT ; Anaelena RODRIGUEZ ; Orry MARCIANO ; Rachel NORDGREN ; Scott D LUNDY ; Omer A RAHEEM
Asian Journal of Andrology 2025;27(4):464-469
This study was to survey the relationship between semen values and demographics, comorbidities, and recreational substance use in a large cohort of adult men at the University of Chicago Medical Center Department of Urology (Chicago, IL, USA). We performed an analysis from January 2013 to December 2023 of semen samples obtained from adult patients at our institution and collected their demographics, comorbid medical conditions, and recreational substance use information. Patients were divided into categories of normozoospermia, oligozoospermia, and azoospermia on the basis of the 5 th version of the World Health Organization (WHO) guidelines. Data were analyzed by univariate linear and logistic regression models, after which statistically significant variables were placed into multivariable models. Azoospermia and oligozoospermia were both associated with Caucasian or Black, Indigenous, and People of Color (BIPOC) race (both P < 0.001), increasing age ( P = 0.005 and P < 0.001, respectively), anemia ( P < 0.001 and P = 0.02, respectively), lifetime tobacco use (both P < 0.001), lifetime alcohol use ( P = 0.02 and P < 0.001, respectively), and lifetime use of at least two recreational substances ( P < 0.001 and P = 0.003, respectively) in multivariable models. Oligospermia was additionally associated with benign prostatic hyperplasia (BPH; P = 0.003) in multivariable models. This study suggests that at-risk populations may benefit from additional early screening and workup for infertility.
Humans
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Male
;
Adult
;
Longitudinal Studies
;
Middle Aged
;
Semen Analysis
;
Life Style
;
Oligospermia/epidemiology*
;
Azoospermia/epidemiology*
;
Comorbidity
;
Midwestern United States/epidemiology*
;
Young Adult
9.Association and Interaction between Multidimensional Lifestyle, Socioeconomic Status and the Incidence of Lung Cancer.
Haotian LIU ; Runhuang YANG ; Haiping ZHANG ; Shiyun LV ; Bo GAO ; Lixin TAO ; Yanxia LUO ; Xiuhua GUO
Chinese Journal of Lung Cancer 2025;28(7):497-505
BACKGROUND:
The incidence and mortality rates of lung cancer remain on the rise, creating an urgent need for screening among high-risk populations and early prevention. This study aims to explore the association and interaction between multidimensional lifestyle, socioeconomic status, and the incidence of lung cancer, and to provide scientific evidence for screening high-risk populations and preventing lung cancer.
METHODS:
Healthy lifestyle score was constructed using information on smoking, alcohol consumption, exercise, diet and sleep obtained through a questionnaire survey. Socioeconomic status was evaluated based on information on education, employment, and family income, and genetic testing data were used to assess the risk of genetic variation. A proportional hazards assumption test was conducted, and the Cox proportional hazards model was applied to analyze the associations between healthy lifestyle scores, socioeconomic status, and lung cancer, as well as the interactions among various factors, after adjusting for the risk of genetic variation, age, gender, diabetes, hypertension and the living environment score.
RESULTS:
A total of 245,538 samples that entered the cohort from March, 2006 to October, 2010 were included and followed up until December 31, 2022. The participants were divided into the case group (n=1472) and the control group (n=244,066). The analysis results showed that after adjusting for covariates, there was still an association between the healthy lifestyle score, socioeconomic status, and the incidence of lung cancer: compared with participants with a high healthy lifestyle score, the risk of lung cancer in participants with medium and low healthy lifestyle scores was significantly increased, with hazard ratios (HR) of 2.12 (95%CI: 1.86-2.41) and 3.36 (95%CI: 2.82-3.99) respectively; compared with participants with high socioeconomic status, the risk of lung cancer in participants with medium and low socioeconomic status was significantly increased, with HR of 1.29 (95%CI: 1.13-1.48) and 1.67 (95%CI: 1.46-1.90) respectively. Moreover, there were interactions between smoking status and socioeconomic status (Pfor interaction=0.05), as well as the other four lifestyle factors (Pfor interaction=0.02).
CONCLUSIONS
This study identified the association between multidimensional lifestyle factors and socioeconomic status with the incidence of lung cancer, as well as interactions between smoking and socioeconomic status and four other lifestyle factors, providing a scientific basis for screening and prevention in high-risk populations for lung cancer.
Humans
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Lung Neoplasms/epidemiology*
;
Male
;
Female
;
Middle Aged
;
Incidence
;
Life Style
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Social Class
;
Aged
;
Adult
;
Risk Factors
10.Associations between mental health and lifestyle changes during the COVID-19 pandemic in a general Japanese population: NIPPON DATA2010.
Naoki AONO ; Aya HIGASHIYAMA ; Harumitsu SUZUKI ; Akira FUJIYOSHI ; Makiko ABE ; Atsushi SATOH ; Hisatomi ARIMA ; Nobuo NISHI ; Aya KADOTA ; Takayoshi OHKUBO ; Tomonori OKAMURA ; Nagako OKUDA ; Akira OKAYAMA ; Katsuyuki MIURA
Environmental Health and Preventive Medicine 2025;30():28-28
BACKGROUND:
Deterioration in lifestyle associated with poor mental health could be an important concern during the coronavirus disease 2019 (COVID-19) pandemic. However, few studies have investigated the association between mental health status and lifestyle changes during the pandemic in nationwide Japanese general population.
METHODS:
This cross-sectional study was conducted using the data among 1,546 participants of the follow-up study of NIPPON DATA2010 in 2021. Recent mental status, as assessed using the Kessler 6 (K6) scale, and lifestyle changes compared to before the pandemic were determined using self-reported questionnaires. Some lifestyle changes such as decreased physical activity were defined as undesirable, whereas others such as decreased alcohol drinking were defined as desirable. The participants were divided into three groups based on the K6 scores: the K6<5, 5≤K6<9, and K6≥9 groups. The odds ratios (ORs) and 95% confidence intervals (CIs) of the K6 groups for each lifestyle change compared with that in the K6<5 group were estimated after adjusting for possible confounders.
RESULTS:
The ORs of the K6≥9 group for all undesirable lifestyle changes were significantly high, especially increased alcohol drinking (OR 4.64; 95% CI, 2.71-7.93), and decreased physical activity (OR 4.63; 95% CI, 3.29-6.52). Among the desirable changes, the OR of the 5≤K6<9 group was significantly high for increased eating home cooking.
CONCLUSIONS
Poor mental health showed a significant association with undesirable lifestyle changes, especially increased alcohol drinking and decreased physical activity, in a nationwide general Japanese population during the COVID-19 pandemic.
Humans
;
COVID-19/epidemiology*
;
Japan/epidemiology*
;
Male
;
Female
;
Mental Health/statistics & numerical data*
;
Middle Aged
;
Cross-Sectional Studies
;
Life Style
;
Adult
;
Aged
;
Exercise
;
Alcohol Drinking/epidemiology*
;
SARS-CoV-2
;
Pandemics
;
East Asian People


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