Objective A pronunciation aid device had been made by using dental prosthodontic method for the treatment of pronunciation disorder, which is caused by movement dysfunction because of defect of soft palate tissues in cleft lip and palate patients.Methods According to the defect condition in the mouth, two types of pronunciation aid devices had been produced regularly by using maxillary impression, plaster casting and thermoplastic resin materials and so on. Results In the first group of cases, after 3 patients were wearing soft palate movement pronunciation aid device, and then they were given pronunciation training, it is found that their language clearances degrees had been promoted obviously. In the second group of cases, 2 patients were wearing naso-pharynx cavity closing pronunciation aid device, it is found that their nasal sound and nasal leakage were disappeared. And in the same time we gave patients pronunciation training, and after one year, their language clearances degrees were found to be more obviously increased than before.Conclusions Naso-pharynx cavity closing pronunciation aid device and soft palate movement pronunciation aid device are an effective non-surgical treatment methods for the treatment of naso-pharynx cavity closing dysfunction and soft palate movement dysfunction.

Objective To observe the different efficacy of combination of inhaled ipratropium bromide and salbutamol and inhaling the two drugs separately. Methods Sixty -five patients with COPD were divided into 3 groups,and treated with different drugs. We observed the lung function FEV1 , the improvement of symptoms and side - effects. Results The FEV_1 and improvement of symptoms in combination group were significantly better than those in seperatin group (P

The guidelines for the diagnosis and treatment of acute pancreatitis are the important reference for clinicians in treating acute pan-creatitis,especially severe acute pancreatitis (SAP).However,currently there is much discrepancy on the opinion and practice in China, which affects the treatment outcome and cure rate of this disease.Clinical focuses are described in terms of the diagnostic criteria and treat-ment for SAP,with the hope of initiating reflection and discussion on the clinical diagnosis and treatment of SAP.

That provincial hospital hosting the local hospital is an important measure to deepening the reform of medical and health system.Advanced hospital management mechanism and excellent technical experts were gradually introduced into the local hospital to establish South Hubei healthcare alliance,and form province-city-county healthcare alliance.In this way,high quality management,manpower and technology resource sink,overall medical technology level achieves good breakthrough.This promotes the rapid development of healthcare alliance member hospitals in the region.

Fluid Therapy ; Humans ; Rehydration Solutions

China ; Humans ; Infant, Newborn ; Intensive Care Units, Neonatal ; trends ; Neonatology ; trends

Objective Using hypothyroid,hyperthyroid and normol control rats model,we investigated mRNA expression of the nerve-growth-factor and its receptor TrkA in hippocampus and parietal cortex at 14,21,28days of ages,to offer a possible neurobiological explanation about mechanism of thyroid hormone modulating NGF and its receptor TrkA.Methods For hypothyroid group,rats were reared with 0.02% methimazol water from 5~6 day of gestation to the day when they were sacrificed;for hyperthyroid group,rats were daily intraperitoneal injected of 0.4?g/g body weight tiiodothyronin from beginning of delivery;for normal control rats were reared a normol diet and water.NGF mRNA and TrkAmRNA were measured by in site hybridization.Results The peak of mRNA expression of NGF and TrkA is at P21and P28 respectively,.The mRNA expression of NGF and TrkA in hypothyroid rats was significantly lower than that in age-matched euthyroid at P14,P21,P28(P

Objective: Analysis of adult attachment in a very stressful situation, i.e., surgery. Methods: Two widely used adult attachment measurements --Relationship Questionnaire(RQ) and Experiences in Close Relationship Inventory(ECR)-are administered to 50 surgery patients in a hospital. Their personal information is also collected. Results: The distribution of 50 patients' adult attachment is: 18(36%) of them are secure, 20(40%) Dismissing, 6(12%) Preoccupied, 6(12%) Fearful. Moreover, attachment anxiety measured by ECR has negative correlation with model-of-self measured by RQ (P

Phosphodiesterases(PDEs) is the only protein enzyme family,which catalyze the hydrolysis of cyclic nucleotide second messages(cAMP and cGMP).PDEs regulate many physiologic and pathologic processes.Recent advance showed that PDE7 hydrolyze cAMP exclusively and is divided into PDE7A and PDE7B. PDE7 mainly express in immune and inflammatory cells.The selective inhibition of this family generates profound,functional effects and PDE7 has been used as a therapeutic target for diseases related with inflammation,such as chronic obstructive pulmonary disease(COPD),rheumatoid arthritis and Alzheimers disease(AD).

Objectives To observe anatomical location of the top branch of plantaris arch which extends from the superficial branch of the medial plantar artery,design and apply flap base on it. Methods On the basis of the anatomical data from 8 feet of 4 fresh cadavers and probed of the Doppler from 50 feet of normal person,defined the anatomic location and body surface projection of the top branch of plantaris arch,a type of new flap design were introduced in the paper. Results The flaps have been used in six cases clinically to treat skin defect of the hand meanwhile,sensation of the flap was regained by suturing nerve.All flaps survived,the appearance of the flaps were excellent,the function of the injured hands were recovered well. Conclusions The design of the flap is reasonable,it is suitable that the free medialis pedis flap of the top branch of plantaris arch is used to repair a small skin defect of the hand.