Studies on the effective methods and mechanism for the treatment of patients with functional ejaculatory incompetence were pursued on the basis of clinical practice. 90 patients with functional ejaculatory incompetence were treated by giving the electromagnetic stimulation to their pudendal nerve and the vibrational massage to their penis. Then the excitation conductive time and velocity of their pudendal nerve were simultaneously determined by the electro-neurophysiology technique. Of the 90 patients with functional ejaculatory incompetence, 69(76.7%) obtained cured effects, 19(21.1%) notable effects and 2(2.2%) improved effects. The total effective rate was 100%. The excitation conductive time and velocity of their pudendal nerve were both significantly different from those before treatment (P < 0.05). These suggest that it is practical to reach the ejaculatory threshold, trigger the ejaculatory reflex and complete the process of ejaculation because the nerve with improved excitational conductibility may release more acetylcholine from is endings after the electromagnetic stimulation to nerve and the vibrational massage to penis.
Adult ; Ejaculation ; Electric Stimulation Therapy ; Humans ; Male ; Massage ; Sexual Dysfunction, Physiological ; therapy ; Treatment Outcome ; Vibration

To probe further into the viscosity of gastrointestinal mucus, the samples of gastrointestinal mucus were taken from fifty normal people and were tested with Low-Shear 30 viscometer, and then the viscosity model was obtained. The results indicated that the apparent viscosity of large intestine mucus is greater than that of small intestine and stomach. The gastrointestinal mucus is a kind of non-Newtonian fluid when its apparent viscosity rapidly decreases with the increase of shear rate. When the shear rate increase well enough, the apparent viscosity of gastrointestinal mucus becomes a constant, and the gastrointestinal mucus appears to be a Newtonian fluid.
Adolescent ; Adult ; Aged ; Female ; Gastrointestinal Tract ; chemistry ; Humans ; Male ; Middle Aged ; Mucus ; chemistry ; Rheology ; Viscosity ; Young Adult

In this paper is reported a new approach for the treatment of sarcoma--electroporation therapy. Electroporation can accelerate pharmacal molecules into cytoplasm by transient electromagnetic pulses. We have utilized the phenomenon of electroporation treating the S-180 sarcomas in the hind legs of the Kunming mice by intratumoral injection of anti-tumor agent at low dose. From the experiment, we learned that this approach can bring about remarkable effect. The technical procedure is easy to do and easy to control. Especially, it is useful in curing the flat tumor and has little untoward side effect. It deserves to be recommended as a new approach to treating the tumor in clinics.
Animals ; Antineoplastic Agents ; therapeutic use ; Apoptosis ; drug effects ; Cell Line, Tumor ; Cyclophosphamide ; therapeutic use ; Electrochemotherapy ; methods ; Mice ; Neoplasm Transplantation ; Sarcoma 180 ; drug therapy ; pathology

The bovine jugular veins were divided into two groups and treated with 4% EX-313 and 0.5% glutaraldehyde respectively, and then they were examined with naked-eye, microscope and scanning electron microscope. Biomechnics test and dorsal implantation in rats were performed. The aquired data were processed and subjected to t-test. The EX-313 fixed material was more pliable than the glutaraldehyde treated material, and the former had higher anticalcification than the latter. In conclusion, the hydrophilia crosslinking agent EX-313 is superior to glutaraldehyde in treating biomaterials, and the bovine jugular vein tanned with EX-313 should be a promising material for repairing in cardiovascular surgery.
Animals ; Bioprosthesis ; Blood Vessel Prosthesis ; Cattle ; Cross-Linking Reagents ; pharmacology ; Glutaral ; pharmacology ; Jugular Veins ; drug effects ; Materials Testing ; Rats ; Rats, Sprague-Dawley ; Tissue Engineering

This investigation was amied at the infiltrative capability of the machinable-infiltrated-ceramic(MIC) glass and the color of the composite after the MIC glass infiltrated through the aluminous matrix with different packing densities. By heating the components to 1100 degrees C for 2 hours, the MIC glass was made to infiltrate through the aluminous matrix with different packing densities. We measured the infiltrative depth and the color parameter and observed the rupture surface of the composite by means of SEM. There was a linear relation between the square of infiltrative depth and the packing density of aluminous matrix. The minimal depth was 3.092 mm. No relationship was noted between the composite's color coefficient and the packing density of aluminous matrix. In the rupture process of the composite, crack deflexion, crystal evulsion, and rupture through crystal could be observed. This experiment proved that the infiltrative characters of MIC glass meet the clinical requirement, the composite's color is steady and the mechanical intensity is stable.
Aluminum Oxide ; chemistry ; Ceramics ; chemistry ; Color ; Dental Porcelain ; chemistry ; Hardness ; Materials Testing ; Osmosis

This study aims at the mechanism of foveola formation in bovine trabecular bone under fatigue process and its relation with biomechanical pathogenesis of senile osteoporosis. The scanning electron microscope equipped with fatigue stage was used to observe fatigue micro injury accumulation of cancellous bone. The massive foveola formation in the laminal bone of vertical trabeculae was found in the tensile fatigue test. There existed the collagen avulsion in the foveola. The massive foveola formation was also observed in the lamina bone of the horizontal trabeculae in the compressive fatigue test. The bone collagen fibers were protracted, debound with hydroxyapatite crystal, and then avulsed under tensile and bending stresses. Finally the retraction of the avulsed collagen fibers brought on the massive formation of foveolae in lamina bone. The mechanical capacity of bone also declined greatly. We infer that the direct mineralization of avulsed collagen and foveola in lamina bone would be one of the main processes of self repair in vivo, which brings on the increase in fragility and stiffness of trabeculae of senile osteoporotic bone along with the agelong accumulation of collagen fatigue injury and foveola formation in the lamina bone.
Animals ; Bone and Bones ; pathology ; ultrastructure ; Cattle ; Collagen ; ultrastructure ; Compressive Strength ; Durapatite ; chemistry ; In Vitro Techniques ; Microscopy, Electron, Scanning ; Models, Biological ; Stress, Mechanical ; Tensile Strength

The phase constitution, microstructure and properties of a new type of machinable glass-ceramics containing fluorophlogopite-type (FPT) Ca-mica for used in restorative dentistry were investigated. According to the results of X-ray diffraction (XRD) and energy-dispersive spectrometry(EDS), its main crystalline phases were FPT Ca-mica and t-ZrO2, together with few KxCa(1-x)/2Mg2Si4O10F2, m-ZrO2. The flexible strength was 235 MPa, which was nearly two times larger than that of the present mica-based dental materials, and the highest fracture toughness was 2.17 MPa.m1/2. The microstructure had a great effect on properties, the glass-ceramics contained a large volume, and the fine crystals showed higher strength. The material possessed typical microstructure of machinable glass-ceramics and displayed excellent machinability during drilling test and CAD/CAM.
Aluminum Silicates ; Biomechanical Phenomena ; Ceramics ; Dental Materials ; Hardness ; Materials Testing

This study sought to explore the change of the major histocompatibility complex (MHC) antigen expression and the endothelization of blood vessel in minor pig after trypsin treatment, and to provide data for xenotransplantation and pig vessel for use in tissue engineering. Western blot assays were conducted for detecting the expression of MHC xenoantigens. Scanning electron microscopy was used for checking the endothelization of decellularized blood vessel. The results showed that MHC antigen is not expressed after trypsin treatment. The endothelization is accomplished. The endothelial cells have normal morphological distribution. These demonstrate that the antigen of pig aorta is significantly decreased and it can be used for constructing new vascular grafts.
Animals ; Bioprosthesis ; Blood Vessel Prosthesis ; Cells, Cultured ; Endothelial Cells ; cytology ; Female ; Major Histocompatibility Complex ; physiology ; Male ; Swine ; Swine, Miniature ; Tissue Engineering ; methods ; Tissue Scaffolds

The relapse after orthognathic surgery was frequently reported in recent years. But up to now researches concerning bio-mechanic mechanism of relapse are rare. The purpose of this study, by imitating the operation on monkeys, was to examine the biomechanical properties and histological characteristics after operation in order to investigate the mechanism of the relapse after orthognathic surgery. 20 rhesus monkeys divided into two groups were subjected to bilateral sagittal split and oblique osteotomy, respectively. The broken strength, stress and strain of the operated sites were examined with the use of biomechanical methods, and the healing scab was observed using histological method and SEM at 3, 6, 12, 24 weeks after operation. The results obtained demonstrated that bone healing and biomechanical properties reached certain level after 6 to 12 weeks' recovery in both operation groups; the biomechanical properties and histological characteristics recovered faster in sagittal split group than in oblique osteotomy group. Histological examination also demonstrated similar results. From the data above it is suggested that the higher relapse rate in sagittal split may more closely related to the mechanical effect different from the scab healing, although 8 weeks' fixation may meet the requirement of clinical treatment, accessory fixation method should be adopted after the removal of inter-maxilla fixation.
Animals ; Biomechanical Phenomena ; Bone Regeneration ; Female ; Fracture Healing ; Macaca mulatta ; Male ; Mandible ; pathology ; surgery ; Osteotomy ; methods ; Recurrence

The enzyme histochemistry method was used in this experiment to study the biocompatibility of the UV surface modified Dacron. The activity of the enzymes such as ALP, ACP, NADHD and LDH in the tissue surrounding both the modified and unmodified materials after a certain implantation period was semiquantitatively measured. The results showed that the biocompatibility of the surface modified Dacron was as good as that of the unmodified one.
Biocompatible Materials ; Heart Valve Prosthesis ; Materials Testing ; Polyethylene Terephthalates ; radiation effects ; Surface Properties ; Ultraviolet Rays