No abstract available.
Anniversaries and Special Events* ; Hemorrhage* ; Liver* ; Shock*

No abstract available.
Breast Neoplasms* ; Breast*

No abstract available.
Rupture* ; Spleen*

Nuclear DNA content in 31 cases of thyroid neoplasm was determined by flow cytometry with the use of paraffin-embedded archival tissue. DNA aneuploidy was found in 6 cases (19.4%) of the 31 thyroid neoplasms; such as 2 of 8 (DI=1.16, 1.56) follicular adenomas, 1 of 6 (DI=1.10) follicular carcinomas, 1 of 15 (DI=1.18) papillary carcinomas and 2 of 2 (DI=1.76, 2.07) medullary carcinomas. The remaining tumors were diploid. No significant difference between follicular adenomas and carcinomas was detected with respect to the S phase fraction(SPF). In the papillary carcinoma group the SPF was higher than in the follicular neoplasm group, but it was statistically insignificant. Regional lymph node metastasis was present in 8 of 15( 53.3%) papillary carcinomas but absent in all of the 14 follicular neoplasms. In the medullary carcinoma group one case showed regional node metastasis at the time of resection and the other developed metastasis 11 months after surgical removal of the primary lesion. In this study tumors predominantly composed of Hurthle cells were found to have a significantly higher D.I. than those with few or no Hurthle cells. No significant difference was found between tumors with metastasis and those without metastasis.
Adenoma ; Neoplasm Metastasis

PURPOSE: Primary small bowel cancer is rare. In many cases, the diagnosis is difficult especially in jejunum and ileum, confirmed in advanced state with poor prognosis. This study was intended to clarify the characteristics of primary small bowel cancer. MATERIAL AND METHOD: We have reviewed 24 patients with primary small bowel cancer that have been operated at the Department of Surgery, hospital from Jan. 1990 until Dec. 1996. The clinical feature, diagnostic method, location and histologic finding of tumor, prognosis were analyzed. RESULTS: 1. The ratio of male to female was 1:1.18. The mean age was 53 years and the most prevalent age group was 6th decade (13 cases, 54.1%). 2. The most common primary site was jejunum (9 cases), followed by duodenum (8 cases) and ileum (7 cases). Leiomyosarcoma occurred most frequently in jejunum, adenocarcinoma in duodenum, and lymphoma in ileum. 3. The most common symptom was abdominal pain (66.7%), followed by anemia (54.2%), palpable mass (50%). 4. The accuracy rate of preoperative diagnosis or suspicion was 45.8%, and diagnostic measures were endoscopy in duodenum, small bowel series and/or abdominal CT. in jejunum and ileum. 5. Curative resection was performed in 14 cases (58.3%), and the cancer in which palliative resection was undertaken most frequently was leiomyosarcoma. 6. The mean follow-up period of 23 cases except 1 was 33 months, during this time 9 cases were dead, of whom 5 cases had leiomyosarcoma. CONCLUSION: Frequently, small bowel cancer is difficult in diagnosis, confirmed in late stage. High degree of suspicion and more endeavor to discover it is important and needed to bring a better result.
Abdominal Pain ; Adenocarcinoma ; Anemia ; Diagnosis ; Duodenum ; Endoscopy ; Female ; Follow-Up Studies ; Humans ; Ileum ; Jejunum ; Leiomyosarcoma ; Lymphoma ; Male ; Prognosis ; Tomography, X-Ray Computed

We retrospectively analyzed 40 adrenalectomies due to 13 cases of primary aldosteronism, 12 cases of Cushing's syndrome and 15 cases of pheochromocytoma, which were performed at Chungnam National University Hospital during the last 10 years. Of the 25 patients who presented with adrenal cortical tumors(primary aldosteronism and Cushing's syndrome), 23 had an adenoma and two had cortical hyperplasia. The overall ratio of males to females was 2:1. As to the age distribution, primary aldosteronism was predominant in the 4th and the 5th decades and Cushing's syndrome; in the 3rd and the 4th decades; however, pheochromocytoma was almost evenly distributed in 2nd through the 6th decades. Headaches, fatigue, and general weakness were the most frequent symptoms in primary aldosteronism; weight gain or a change in fat distribution in Cushing's syndrome; and headaches or blurred vision related to hypertension and palpitation in pheochromocytoma. Postoperative complications mostly occurred in patients with Cushing's syndrome: There were four wound infections, including one abdominal abscess, one pleurisy, one cerebral and cerebellar infaction, and two intestinal obstructions, but there were no postoperative deaths.
Abdominal Abscess ; Adenoma ; Adrenalectomy ; Age Distribution ; Chungcheongnam-do ; Cushing Syndrome ; Fatigue ; Female ; Headache ; Humans ; Hyperaldosteronism ; Hyperplasia ; Hypertension ; Intestinal Obstruction ; Male ; Pheochromocytoma ; Pleurisy ; Postoperative Complications ; Retrospective Studies ; Weight Gain ; Wound Infection

We retrospectively analyzed 40 adrenalectomies due to 13 cases of primary aldosteronism, 12 cases of Cushing's syndrome and 15 cases of pheochromocytoma, which were performed at Chungnam National University Hospital during the last 10 years. Of the 25 patients who presented with adrenal cortical tumors(primary aldosteronism and Cushing's syndrome), 23 had an adenoma and two had cortical hyperplasia. The overall ratio of males to females was 2:1. As to the age distribution, primary aldosteronism was predominant in the 4th and the 5th decades and Cushing's syndrome; in the 3rd and the 4th decades; however, pheochromocytoma was almost evenly distributed in 2nd through the 6th decades. Headaches, fatigue, and general weakness were the most frequent symptoms in primary aldosteronism; weight gain or a change in fat distribution in Cushing's syndrome; and headaches or blurred vision related to hypertension and palpitation in pheochromocytoma. Postoperative complications mostly occurred in patients with Cushing's syndrome: There were four wound infections, including one abdominal abscess, one pleurisy, one cerebral and cerebellar infaction, and two intestinal obstructions, but there were no postoperative deaths.
Abdominal Abscess ; Adenoma ; Adrenalectomy ; Age Distribution ; Chungcheongnam-do ; Cushing Syndrome ; Fatigue ; Female ; Headache ; Humans ; Hyperaldosteronism ; Hyperplasia ; Hypertension ; Intestinal Obstruction ; Male ; Pheochromocytoma ; Pleurisy ; Postoperative Complications ; Retrospective Studies ; Weight Gain ; Wound Infection

Extrapelvic endometriosis is a rare disease. The majority of extrapelvic endometriosis cases involve scar tissue following obstetric and gynecologic procedures. We have treated two cases of extrapelvic incisional endometriosis. A 39 year old female patient with cyclic vaginal spotting after laparoscopic assisted vaginal hysterectomy due to uterine myoma and a 35 year old female patient with a painful palpable abdominal mass after cesarean section. Both underwent complete excision and were proven to have endometriosis by pathology. Here we report on both cases and review the medical literatures.
Adult ; Cesarean Section* ; Cicatrix ; Endometriosis* ; Female ; Humans ; Hysterectomy, Vaginal* ; Leiomyoma ; Metrorrhagia ; Pathology ; Pregnancy ; Rare Diseases

Splenic hamartomas are rare benign tumors, which are usually small in size and asymptomatic and which are discovered incidentally at surgery or autopsy. The authors report on a case of splenic hamar toma in a 35-year-old man with intermittent left upper quardrant pain, who underwent an elective splenc tomy. Final pathology confirmed diagnosis of a hamartoma of the red pulp in the spleen. The patient's symptoms were resolved after the splenectomy. A splenic hamartoma should be kept in mind in the differential diagnosis of splenic tumors. The authors suggest that a splenectomy is indicated in cases where malignancy cannot be excluded and in cases of associated clinical symptoms or hematologic disorders.
Adult ; Autopsy ; Diagnosis ; Diagnosis, Differential ; Hamartoma* ; Humans ; Pathology ; Spleen* ; Splenectomy

PURPOSE: The purpose of this study was to evaluate the cognitive effects of chemotherapy in patients with breast cancer. METHODS: Using several databases, prospective studies were collected up to August 2011. Of 2,106 publications identified, 12 met the inclusion criteria, and 8 studies were used to estimate the effect size of chemotherapy on cognitive impairment. RESULTS: Twelve studies were done since 2005 and most of the research was performed in Europe or North America. Eight studies were used to generate effect size across the cognitive domains of attention/concentration, verbal and visual memory, executive function, visuospatial skill, language, and subjective cognitive function. Each of the cognitive domains showed small effect sizes (-0.02 ~ -0.26), indicating diminished cognitive function for the chemotherapy group compared with non-chemotherapy groups. CONCLUSION: Finding suggests that breast cancer patients who undergo chemotherapy may experience mild cognitive decline. Further study is needed to generate knowledge and guideline for interventions to address chemotherapy related cognitive impairment in these patients.
Antineoplastic Agents/adverse effects/*therapeutic use ; Breast Neoplasms/*drug therapy ; Cognition Disorders/*physiopathology ; Databases, Factual ; Female ; Humans ; Language Tests ; Memory, Short-Term ; Neuropsychological Tests