No abstract available.
Knee* ; Nevus* ; Organoids*

No abstract available.
Epidermal Cyst* ; Herpes Zoster*

Proliferating trichilemmal tumor (PTT) is an uncommon neoplasm originated from the outer root sheath of a hair follicle. Malignant transformation occurs occasionally in proliferating trichilemmal tumors, which can be manifested by sudden rapid growths. Histologically, the malignant proliferating trichilemmal tumors (MPTTs) have shown severe nuclear atypia, marked cellular pleomorphism with atypical mitoses, dyskeratotic cells and infiltrating margins. Squamous cell carcinoma (SCC) should be differentiated with MPTT which indicates characteristic trichilemmal keratinization. Large tumor is considered as a risk factor of metastasis in SCC, but the relationship between tumor size and metastasis in the MPTT is not yet clarified. In this report, two patients have large erythematous nodules with focal ulceration and necrosis on their scalps and were diagnosed as MPTT. Despite the large sizes of the tumors, there were no evidences of metastases. Herein, we report 2 cases of the large MPTT which are presented without metastasis.
Carcinoma, Squamous Cell ; Hair Follicle ; Humans ; Mitosis ; Necrosis ; Neoplasm Metastasis* ; Risk Factors ; Scalp* ; Ulcer

No abstract available.
Dermatitis, Allergic Contact

No abstract available.
Adult ; Humans

No abstract available.
Angiofibroma ; Carbon ; Carbon Dioxide ; Lasers, Gas

BACKGROUND: Acquired bilateral nevus of Ota-like macules (ABNOM) is a dermal pigmented lesion common in individuals of Oriental origin. The Q-switched Nd:YAG laser (QSNYL) has been used successfully to treat a variety of benign, dermal, pigmented lesions, including nevus of Ota lesions. The similarity between ABNOM and nevus of Ota suggested that QSNYL may also be effective in the former. OBJECTIVE: To determine the efficacy and side-effect profiles of QSNYL treatment of ABNOM in Korean patients. METHODS: Of 42 Korean patients with ABNOM, 29 were treated with QSNYL (1,064 nm, 3 mm spot size, fluence 8~9.5 J/cm2), for up to 10 sessions each. Clinical photographs were taken before and after treatment. Lesion clearance was graded and complications such as hyperpigmentation, scarring, hypopigmentation, and erythema were assessed. RESULTS: Of the 29 treated patients, 19 (66%) showed excellent or good results. Of the patients who were treated more than 3 times, 76% showed good to excellent results. Two patients experienced post-laser hyperpigmentation (PLH), which persisted for more than one month, but no patient experienced persistent erythema or hypertrophic scarring. CONCLUSION: QSNYL is safe and effective in the treatment of ABNOM in Korean patients. Short-interval repetitive treatment is especially useful in improving therapeutic results and reducing PLH.
Cicatrix ; Cicatrix, Hypertrophic ; Erythema ; Humans ; Hyperpigmentation ; Hypopigmentation ; Laser Therapy ; Nevus ; Nevus of Ota

Spindle cell lipoma is a benign tumor composed of ropey collagen, myxoid stroma, CD34-positive spindled cells, and mature fat. The variable proportion of these elements among different cases of the neoplasm makes diagnosis difficult. Furthermore, numerous variants have been reported, including pseudoangiomatous spindle cell lipoma, angiomatous spindle cell lipoma, fibrous spindle cell lipoma, and low-fat or fat-free spindle cell lipoma. Here we report a case of low-fat, fibrous spindle cell lipoma in which fat is noted to be present in <5% of the tumor, whereas fibrous collagenous stroma is predominant.
Collagen ; Lipoma

Trichodiscoma are hamartomas of the dermal portion of the hair disc, and these are found as asymptomatic flesh- colored papules 1~3 mm in diameter, and they are usually located on the face, trunk and thigh. Histopathologically, this is characterized by non-encapsulated fibrovascular lesion with a myxoid stroma surrounded by folliculo- sebaceous units. Birt-Hogg-Dube syndrome, which develops multiple trichodiscomas with fibrofolliculomas and skin tags, has been described. The case of solitary trichodischoma is rare. We recently encountered a 29-year-old woman with a solitary, dome-shaped papule on the right thigh. After histopathologic examination, the lesion was diagnosed as trichodiscoma.
Adult ; Birt-Hogg-Dube Syndrome ; Female ; Hair ; Hamartoma ; Humans ; Skin ; Thigh

Although injectable soft-tissue augmentation materials are extremely well-tolerated, undesirable effects sometimes occur. Whereas minor adverse events such as erythema, edema or bruising are generally reversible, the formation of foreign body granuloma, atypical mycobacterial infections or tissue necrosis may cause serious irreversible damages and disfigurement. We present here the case of a 50-year-old woman with an indurated painful nodule and patch on the right cheek, and this occurred after an unlicensed nonspecialist injected filler of unknown ingredients. The histopathologic findings showed granulomatous inflammation composed of lymphocytes, histiocytes and multinucleated giant cells with a Swiss cheese appearance. Although any acid-fast bacilli were not observed on Ziehl-Neelsen staining, the mycobacterial culture demonstrated an ivory-colored wet colony that was identified as M. chelonae by polymerase chain reaction-restriction fragment length polymorphism. The patient was treated with 1 g of clarithromycin for seven weeks, and the lesion improved considerably.
Cheek ; Cheese ; Clarithromycin ; Edema ; Erythema ; Female ; Foreign Bodies ; Giant Cells ; Granuloma, Foreign-Body ; Histiocytes ; Humans ; Inflammation ; Lymphocytes ; Middle Aged ; Mycobacterium ; Mycobacterium chelonae ; Necrosis