2.Analysis of verification results of protective effects of hearing protectors in different industries.
Han Xue SHI ; Shi Biao SU ; Ming LIU ; Rong Zong LI ; Tian Jian WANG ; Bin XIAO
Chinese Journal of Industrial Hygiene and Occupational Diseases 2023;41(5):333-337
Objective: To get insight into the current practice of noise reduction effect of workers as they wore hearing protectors in different domestic enterprises and the possible affected factors. Methods: From October 2020 to April 2021, using a random sampling method, 1197 workers exposed to noise in petrochemical factories, textile factories, and parts manufacturing factories were selected as the study subjects. The noise reduction effect of hearing protectors worn by workers in daily use was tested using a hearing protector suitability testing system. The personal sound attenuation level (PAR) was compared among workers in three enterprises, Targeted intervention and repetitive testing were conducted for workers who did not meet the noise reduction effect required by the enterprise, and the changes in PAR of workers before and after the intervention were compared. The comparison of baseline PARs between two or more groups was performed using the Mann Whitney test, the comparison of baseline PARs with post intervention PARs was performed using the Wilcoxon signed rank sum test, and the comparison of qualitative data between two or more groups was performed using the Chi square test. Results: The median baseline PAR for all workers was 15 dB. Men, age<30 years old, education level at or above college level, working experience of 5 to 15 years, and those who used hearing protectors for 5 to 15 years had higher PARs, with statistically significant differences (P<0.05). The median difference in baseline PAR among workers from three enterprises was statistically significant (H=175.06, P<0.01). The median PAR of subjects who did not pass the baseline increased from 3 dB to 21 dB after intervention (Z=-27.92, P<0.01) . Conclusion: Some workers wearing hearing protectors do not meet the required PAR, and low PARs may be related to incorrect wearing methods and incorrect selection of hearing protectors. As a tool for testing, training, and assisting in selection, the hearing protector suitability testing system is of great significance for worker hearing protection.
Male
;
Humans
;
Adult
;
Hearing Loss, Noise-Induced/prevention & control*
;
Ear Protective Devices
;
Noise, Occupational/prevention & control*
;
Hearing
;
Audiometry
4.Investigation of protective exposure risk events in nurses against corona virus disease 2019 in Wuhan.
Qiu WANG ; Jin Yu GUO ; Hong SUN ; Ling WANG ; Ju Su YING ; Hui Xin LIU
Journal of Peking University(Health Sciences) 2020;52(4):711-714
OBJECTIVE:
To investigate the current situation of virus exposure risk incidents of nurses against corona virus disease 2019 (COVID-19) in Wuhan, and to provide reference evidence for nursing managers to protect nursing staff who were working in the isolation ward.
METHODS:
In the study, 308 nursing staff against COVID-19 working in the isolation ward in Wuhan were conveniently selected to participate in the investigation. The designed questionnaires including 7 kinds of protective exposure risk events were made by the team of researchers on the basis of literature review and interview with the nurses in Wuhan. All the participants recalled their working experience in the status of dressing in personal protective equipment and filled in the questionnaires online by WeChat according to the same instruction.
RESULTS:
The questionnaires were filled in validly by a total of 304 nursing staff, of whom 88.8% received emergency training on the prevention and dealing measurement of exposure risk events. The incidence of shoe cover contamination, falling off or torn was relatively high, about 53.6%. Due to the protection of gloves, the incidence of hand or skin contamination was relatively low, about 14.1%. The most nervousness of protective exposure risk event for nurses was N95 mask contamination, falling off or shifting, with a score of 8.2±2.3, showing a higher psychiatric burden. Single factor analysis found that the number of days in Wuhan was different, the number of the types of protective risk events occurred was different (χ2=14.562, P=0.024), orderly multivariate Logistic regression found that men were the independent protective factor for the number of the types of protective exposure risk events that occurred (P=0.019).
CONCLUSION
Protective exposure risk events may occur in the work of nursing staff working in the isolation ward in Wuhan. It is necessary to guide nurses to prevent the occurrence of protective exposure risk events and effectively deal with them, so as to prevent virus exposure and reduce psycholo-gical burden.
Betacoronavirus
;
COVID-19
;
China
;
Coronavirus Infections/transmission*
;
Ear Protective Devices
;
Humans
;
Male
;
Occupational Exposure/prevention & control*
;
Pandemics/prevention & control*
;
Pneumonia, Viral/transmission*
;
Risk Factors
;
SARS-CoV-2
5.Case of the Index Patient Who Caused Tertiary Transmission of COVID-19 Infection in Korea: the Application of Lopinavir/Ritonavir for the Treatment of COVID-19 Infected Pneumonia Monitored by Quantitative RT-PCR
Jaegyun LIM ; Seunghyun JEON ; Hyun Young SHIN ; Moon Jung KIM ; Yu Min SEONG ; Wang Jun LEE ; Kang Won CHOE ; Yu Min KANG ; Baeckseung LEE ; Sang Joon PARK
Journal of Korean Medical Science 2020;35(6):79-
Since mid-December of 2019, coronavirus disease 2019 (COVID-19) infection has been spreading from Wuhan, China. The confirmed COVID-19 patients in South Korea are those who came from or visited China. As secondary transmissions have occurred and the speed of transmission is accelerating, there are rising concerns about community infections. The 54-year old male is the third patient diagnosed with COVID-19 infection in Korea. He is a worker for a clothing business and had mild respiratory symptoms and intermittent fever in the beginning of hospitalization, and pneumonia symptoms on chest computerized tomography scan on day 6 of admission. This patient caused one case of secondary transmission and three cases of tertiary transmission. Hereby, we report the clinical findings of the index patient who was the first to cause tertiary transmission outside China. Interestingly, after lopinavir/ritonavir (Kaletra, AbbVie) was administered, β-coronavirus viral loads significantly decreased and no or little coronavirus titers were observed.
China
;
Clothing
;
Commerce
;
Coronavirus
;
Fever
;
Hospitalization
;
Humans
;
Korea
;
Male
;
Pneumonia
;
Thorax
;
Viral Load
6.Cytopathologic Features of Secretory Carcinoma of Salivary Gland: Report of Two Cases
Young Ah KIM ; Jae Won JOUNG ; Sun Jae LEE ; Hoon Kyu OH ; Chang Ho CHO ; Woo Jung SUNG
Journal of Pathology and Translational Medicine 2019;53(1):70-74
Secretory carcinoma of the salivary gland (SC) is a newly introduced rare salivary gland tumor that shares histological, immunohistochemical, and genetic characteristics with secretory carcinoma of the breast. Here, we report the cytologic features of two cases of SC confirmed by surgical resection. In these two cases, SC was incidentally detected in a 64-year-old female and a 56-yearold male. Fine needle aspiration cytology revealed nests of tumor cells with a papillary or glandular structure floating in mucinous secretions. The tumor cells demonstrated uniform, round, smooth nuclear contours and distinct nucleoli. Multiple characteristic cytoplasmic vacuoles were revealed. Singly scattered tumor cells frequently showed variable sized cytoplasmic vacuoles. The cytopathologic diagnosis of SC should be considered when characteristic cytological findings are revealed. Further immunohistochemistry and gene analyses are helpful to diagnose SC.
Biopsy, Fine-Needle
;
Breast
;
Clothing
;
Cytoplasm
;
Diagnosis
;
Female
;
Humans
;
Immunohistochemistry
;
Male
;
Mammary Analogue Secretory Carcinoma
;
Middle Aged
;
Mucins
;
Salivary Glands
;
Vacuoles
7.Efficiency of Air Bubble Removal in Preparation of Low-Profile Angioplasty Balloon Catheter: Bench-Top Comparison of Six Methods
Joon Ho CHOI ; Seon Moon HWANG ; Deok Hee LEE
Neurointervention 2019;14(1):27-34
PURPOSE: Complete removal of air bubbles from balloons for neurovascular angioplasty is cumbersome. We compared the preparation difficulty, air removal efficiency, and air collection pattern of six different balloon catheter preparation methods to propose a better preparation method for both initial and second balloon uses, especially for small-profile angioplasty balloon catheters. MATERIALS AND METHODS: A total of 18 neurovascular angioplasty balloon catheters with nominal diameters of 2 mm were prepared to test six different preparation methods: the instruction for use method (method A), simplified method using a syringe (method B) and four newly devised preparation methods using inflating devices (methods C–F). Serial radiographs were obtained while the balloons were gradually inflated. We measured the time for each preparation and the bubble number, analyzed their distribution in the balloon, and calculated the contrast filling ratio (contrast filling area/total balloon area) for initial and second ballooning. The whole process was repeated three times. RESULTS: The preparation time varied widely (11.5 seconds [method D] to 73.3 seconds [method A]). On initial inflation, the contrast filling ratio at 8 atm was the highest (100%) with methods A and F. On second inflation, the ratio was again highest with method A (99.5%), followed by method F (99.2%). Initial ballooning tended to show a uniform pattern of single bubble in the distal segment of the balloon; in contrast, second ballooning showed varying patterns in which the bubbles were multiple and randomly distributed. CONCLUSION: None of the six methods were able to completely exclude air bubbles from the balloon catheters including the second ballooning; however, the method of repeating aspiration with high-volume inflating device (method F) could be a practical option considering the simplicity and efficiency of preparation.
Angioplasty
;
Angioplasty, Balloon
;
Catheters
;
Clothing
;
Embolism, Air
;
Equipment Failure
;
Inflation, Economic
;
Intracranial Arteriosclerosis
;
Methods
;
Syringes
8.Stem Cells Seeded on Multilayered Scaffolds Implanted into an Injured Bladder Rat Model Improves Bladder Function
Kshitiz Raj SHRESTHA ; Seung Hwan JEON ; Ae Ryang JUNG ; In Gul KIM ; Ga Eun KIM ; Yong Hyun PARK ; Soo Hyun KIM ; Ji Youl LEE
Tissue Engineering and Regenerative Medicine 2019;16(2):201-212
BACKGROUND: To investigate whether human adipose-derived stem cells (hADSCs) seeded on multilayered poly (L-lactide-co-ε-caprolactone) (PLCL) sheets improve bladder function in a rat model of detrusor smooth muscle-removed bladder. METHODS: Male rats were randomly divided into 4 groups: Normal, injury (detrusor smooth muscle-removed bladder), PLCL (detrusor smooth muscle-removed bladder implanted with PLCL sheets), and PLCL + ADSC (detrusor smooth muscle-removed bladder implanted with PLCL sheets seeded with hADSCs). Four weeks after the treatment, physiological, histological, immunohistochemical, and immunoblot analyses were performed. RESULTS: hADSCs were compatible with PLCL sheets. Further, the physiological study of PLCL + ADSC group showed significant improvement in compliance and contractility suggesting the functional improvement of the bladder. Histological, immunohistochemical and immunoblot analyses revealed the uniform distribution of hADSCs in between PLCL sheets as well as differentiation of hADSCs into smooth muscle cells (SMC) which is illustrated by the expression of SMC markers. CONCLUSION: hADSCs seeded on the multilayered PLCL sheets has the potential to differentiate into SMC, thus facilitating the recovery of compliance and contractility of the injured bladder.
Animals
;
Clothing
;
Compliance
;
Humans
;
Male
;
Models, Animal
;
Muscle, Smooth
;
Myocytes, Smooth Muscle
;
Rats
;
Stem Cells
;
Tissue Engineering
;
Urinary Bladder
9.Matrix Production in Chondrocytes Transfected with Sex Determining Region Y-Box 9 and Telomerase Reverse Transcriptase Genes: An In Vitro Evaluation from Monolayer Culture to Three-Dimensional Culture
Md Nazir NOORHIDAYAH ; Ahmad Hafiz ZULKIFLY ; Kamarul Ariffin KHALID ; Ismail ZAINOL ; Zaitunnatakhin ZAMLI ; Munirah SHA'BAN
Tissue Engineering and Regenerative Medicine 2019;16(3):285-299
BACKGROUND: This study aimed to observe the cartilaginous matrix production in SRY (sex determining region Y)-box 9 (SOX9)- and/or telomerase reverse transcriptase (TERT)-transfected chondrocytes from monolayer to three-dimensional (3D) culture.
Alcian Blue
;
Cartilage
;
Chondrocytes
;
Clothing
;
Coloring Agents
;
Eosine Yellowish-(YS)
;
In Vitro Techniques
;
Proteoglycans
;
Real-Time Polymerase Chain Reaction
;
Regeneration
;
Telomerase
;
Tissue Engineering
;
Transfection
10.Sports-related skin conditions
Journal of the Korean Medical Association 2019;62(4):202-208
Skin diseases associated with athletic activities can be classified as skin infections, inflammatory reactions, trauma, and abnormal proliferation, depending on the cause of the condition. Athlete's nodule is a generic term for reactive nodules that occur in athletes. It is particularly common in the foot due to tight sneakers, repetitive pressure or friction, and inappropriate choice of shoes or other sports equipment. The diagnosis of black heel (calcaneal petechiae) should be considered when numerous black spots occur on the soles in patients who frequently engage in abrupt movements, such as starts, stops, or leaps. Palmoplantar eccrine hidradenitis may occur in athletes who play baseball, dance, and climb, activities in which repetitive and strong stimuli are applied to the floor of the hands and feet. Painful fat herniation should be suspected in cases of painful skin-colored firm nodules on the feet of athletes who place a large amount of weight on their feet when moving. Itching, urticaria, angioedema, chest tightness, and syncope occurring within 5 minutes after starting exercise should be suspected to be exercise-induced angioedema/anaphylaxis. Excessive force can cause deformation of nails, as in tennis toe and jogger's toenail. For the diagnosis and treatment of sports-related skin diseases, it is essential to pay attention to patients' hobbies and exercise habits, including sports, and to consider the relationship of those habits with the presumed mechanisms of the skin disease. In addition, thorough pre-exercise warm-ups, increasing strength gradually, and wearing proper equipment will help prevent the occurrence of sports-related skin diseases.
Angioedema
;
Athletes
;
Baseball
;
Dancing
;
Diagnosis
;
Foot
;
Friction
;
Hand
;
Heel
;
Hidradenitis
;
Hobbies
;
Humans
;
Nails
;
Pruritus
;
Shoes
;
Skin Diseases
;
Skin
;
Sports
;
Sports Equipment
;
Syncope
;
Tennis
;
Thorax
;
Toes
;
Urticaria

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