1.Risk Factors for Vasovagal Reactions during Nonoperative Orthopedic Interventions in Outpatient Clinics: A Clinical Evaluation of 1,208 Patients
Mustafa ÖZYILDIRAN ; Mustafa Onur KARACA ; Abdullah MERTER
Clinics in Orthopedic Surgery 2026;18(1):176-183
Background:
Vasovagal reactions (VVRs) are abnormal autonomic responses mediated by the vagus nerve. They can occur during or after interventional procedures and negatively impact patient care. The aim of this study was to evaluate the incidence of VVRs observed during nonoperative orthopedic interventions in outpatient clinics and to analyze the associated risk factors.
Methods:
The data of 1,208 patients who underwent nonoperative orthopedic interventions at a single-center outpatient clinic between December 2023 and December 2024 were retrospectively analyzed. Patients were categorized into 2 groups based on the occurrence of VVR. The clinical data of both groups were analyzed to identify factors associated with VVRs.
Results:
A total of 1,208 patients with a mean age of 54.7 years were included in the study. Among the 1,208 patients included, 51 cases of VVRs were reported (4.2%). The VVR group had a younger mean age (44.2 vs. 55.1 years, p < 0.001) and a higher proportion of females (74.5% vs. 59.2%, p = 0.029) compared to the non-VVR group. Mean visual analog scale (VAS) scores during intervention were higher in the VVR group (6.41 vs. 2.98, p < 0.001), and blood-injury-injection (BII) phobia was more common (39.2% vs. 1.8%, p < 0.001). Fasting time was longer in the VVR group (3.9 vs. 2.8 hours, p = 0.003). No significant differences were observed in hypertension, coronary artery disease, cerebrovascular disease, or asthma between groups (p > 0.05).
Conclusions
Younger age, female sex, higher VAS scores, BII phobia, and longer fasting times were the risk factors for VVRs associated with nonoperative orthopedic interventions.
2.Benchmarking Open-Source Vision Language Models in Orthopedic In-Training Examination:A Comparison with Residents, Domain-Specific Evaluation, and Parameter Scaling
Sunho KO ; Jaewook LEE ; Kyunga KO ; Jihyeung KIM
Clinics in Orthopedic Surgery 2026;18(1):159-166
Background:
Advancing orthopedic care through large language models requires both multimodal processing capabilities for medical images and open-source deployment options for secure in-house operations, yet these remain underexplored in current literature. This study aims to benchmark open-source vision-language models (VLMs) against orthopedic residents using the Orthopedic In-Training Examination (OITE), assess domain-specific performance across orthopedic subspecialties, and investigate the relationship between model parameter size and performance.
Methods:
Six open-source VLMs of varying sizes (Alibaba Qwen2.5-VL-72B-Instruct, Alibaba Qwen2.5-VL-32B-Instruct, Alibaba Qwen2.5-VL-7B-Instruct, Alibaba Qwen2.5-VL-3B-Instruct, Meta Llama-3.2-90B-Vision-Instruct, Meta Llama-3.2-11B-Vision-Instruct) were evaluated using the 2023 OITE (210 questions; 111 with images). Model performance was compared to resident scores from the 2023 OITE technical report. Pearson correlation coefficient was used to assess the association between model size and performance.
Results:
The 2 largest open-source models, Qwen2.5-VL-72B and Llama-3.2-90B, demonstrated performance levels comparable to those of second-year orthopedic residents on the OITE examination. A mid-sized model, Qwen-32B, slightly outscored first-year residents. In contrast, small-sized models (under 11 billion parameters) performed worse than first-year residents. Qwen2.5-VL-72B performed best in foot & ankle and sports medicine topics, while Llama-3.2-90B was strongest in basic science and hand & wrist.All models had the most difficulty with spine and pediatric questions. Overall, model accuracy increased steadily with model size up to 72 billion parameters, but larger sizes showed little additional improvement.
Conclusions
Smaller models offer reduced accuracy in exchange for lower hardware requirements. Spine and pediatric domains remain consistently areas of underperformance across all models. Model selection should be based on domain-specific benchmark results to balance clinical needs with hardware limitations. While promising, open-source VLMs currently require further refinement and validation before they can be reliably applied in clinical or educational settings.
3.Does Preoperative Arthritis Affect the Outcomes of Superior Capsular Reconstruction?A Systematic Review
Tae-Hoon PARK ; Hyungsuk KIM ; Sukil KIM ; Jongin LEE ; Gerald R. WILLIAMS JR ; Hyun Seok SONG
Clinics in Orthopedic Surgery 2026;18(1):122-132
Background:
The optimal indications for superior capsular reconstruction (SCR) in cases of massive irreparable rotator cuff tears (RCTs) accompanied by degenerative arthritis remain controversial.
Methods:
A systematic review was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, searching PubMed, Embase (Elsevier), and Google Scholar. Studies were included if they documented Hamada grade and reported clinical and radiographic outcomes after SCR for irreparable RCTs. American Shoulder and Elbow Surgeons (ASES) score, visual analog scale for pain (pVAS), active range of motion, and acromiohumeral distance (AHD) were analyzed.
Results:
In all 7 studies, there was no consistent trend observed regarding the influence of arthritis on the improvement of ASES scores, and none of the studies showed statistically significant correlations (p > 0.05). All 5 studies regarding pVAS showed a trend that the pVAS improvement after surgery decreased as the severity of arthritis increased (beta coefficient < 0). Out of the 7 studies regarding forward flexion (FF), 6 demonstrated a trend where the improvement after surgery decreased as the severity of arthritis increased (beta coefficient < 0). There was a tendency for the improvement in AHD to increase as the Hamada grade progressed.
Conclusions
There was no consistent trend observed regarding the impact of the severity of arthritis on the improvement of ASES score. However, there was a trend of decreasing improvement in pVAS and FF after surgery as arthritis progressed. SCR could be a viable option even in cases of Hamada grades 3 and 4.
4.Atelocollagen Improves Bone-to-Tendon Interface Healing in a Rabbit Model of Chronic Rotator Cuff Tear Compared with Polydeoxyribonucleotide
Jian HAN ; Zhan-Feng ZHANG ; Shen-Yun FANG ; Yun-Mei CUI ; Sheng Chen HAN
Clinics in Orthopedic Surgery 2026;18(1):167-175
Background:
Surgeons face challenges in selecting cost-effective and biologically active agents for rotator cuff healing, given the numerous commercial products available, such as polydeoxyribonucleotide (PDRN) and atelocollagen (ATC). However, the precise efficacy of PDRN and ATC in rotator cuff healing remains debatable, and there is currently a lack of studies directly comparing the effects of the 2 agents on repaired cuff tendons. Therefore, the purpose of this study was to compare the efficacy of PDRN and ATC on bone-to-tendon interface (BTI) healing using a chronic rotator cuff tear (RCT) model in rabbits.
Methods:
Forty-eight rabbits were randomly divided into 3 groups. To create chronic RCT models, transected tendons were left untreated for 6 weeks, and then were repaired in a transosseous manner with PDRN and ATC injection into the repair site according to group allocation (group A: saline, group B: PDRN, group C: ATC; n = 16 per group). Genetic and immunofluorescence analyses were performed at 4 weeks after surgery. Furthermore, genetic, histologic, and biomechanical analyses were performed at 12 weeks after surgery.
Results:
At 4 weeks after surgery, ATC-injected shoulders showed the highest mRNA expression levels of collagen type I alpha 1 and aggrecan compared to the other 2 groups (p < 0.001 and p = 0.002, respectively). Meanwhile, there was more preliminary fibrocartilaginous matrix formation in the ATC-injected group. At 12 weeks after surgery, ATC-injected shoulders demonstrated better collagen fiber continuity and orientation, denser collagen fibers, a more mature bone-to-tendon junction, and greater fibrocartilage layer formation compared to the other 2 groups (all p < 0.001). Furthermore, ATC-injected shoulders also demonstrated a significantly higher load-to-failure value (40.4 ± 4.5 N/kg) than the remaining groups (group A, 26.7 ± 3.0 N/kg; group B, 32.8 ± 4.2 N/kg; p < 0.001).
Conclusions
ATC demonstrated superior efficacy in promoting BTI healing following surgical repair in a chronic RCT model of rabbits.
5.Red-White Zone Involvement and Medial Meniscal Tears Are Associated with Poorer Prognosis after Arthroscopic Repair of Bucket-Handle Tears
Bo Seung BAE ; Jung Suk KIM ; Sang Hak LEE
Clinics in Orthopedic Surgery 2026;18(1):40-51
Background:
Arthroscopic repair of bucket-handle meniscal tears (BHMTs) is technically challenging owing to the complexity of the tear patterns. Compared to simpler meniscal tears, BHMTs are associated with a higher failure rate and often require subsequent meniscectomy. This study aimed to assess clinical outcomes, failure rates, and risk factors for failure following primary arthroscopic repair of BHMTs.
Methods:
Seventy-four patients (mean age, 27.2 ± 11.2 years) who underwent arthroscopic BHMT repair were included (mean follow-up period, 60.2 ± 36.0 months). Analyzed risk factors included age, sex, body mass index, chronicity, laterality, tear zone, and concomitant anterior cruciate ligament reconstruction. Clinical failure was defined as the presence of clinical symptoms consistent with a meniscus tear and the need for subsequent surgery. The Kaplan-Meier method and log-rank test were performed to compare groups classified by postoperative meniscal healing status on magnetic resonance imaging (MRI) at a mean follow-up period of 7.30 ± 1.80 months. Clinical outcomes were assessed using the Tegner activity score, Lysholm knee score, and Hospital for Special Surgery (HSS) knee score.
Results:
The clinical failure rate was 14.9% (11 / 74). Six patients underwent subtotal meniscectomy, and 5 patients underwent partial meniscectomy. Red-white zone involvement was a significant risk factor for clinical failure (odds ratio, 6.182; 95% CI, 1.093–34.950; p = 0.039). Survival analysis based on postoperative MRI findings revealed a significant difference among 3 groups (p = 0.008): the completely healed group showed a 100% survival rate (20 / 20); the partially healed group, 80% (32 / 40); and the unhealed group, 0% (0 / 5). Patients with lateral BHMTs had a significantly higher rate of complete healing than those with medial BHMTs (46.4% vs. 18.9%; p = 0.014). At the final follow-up, the non-failure group demonstrated significantly higher Tegner activity (5.1 ± 1.2 vs. 4.4 ± 0.5; p = 0.038), Lysholm knee (87.7 ± 6.2 vs. 83.2 ± 3.1; p = 0.029), and HSS knee (93.9 ± 4.7 vs. 89.6 ± 3.0; p = 0.007) scores than the failure group.
Conclusions
BHMTs involving the red-white zone or located in the medial meniscus—particularly those showing inferior early postoperative MRI healing—should be closely monitored after surgery.
6.Evaluation of the Angle Deviation between Pilot Holes and Actual Implanted Pedicle Screw Trajectories in Freehand Pedicle Screw Placement for Thoracolumbar Spine Surgery: The Impact of Tapping and Work Experience
Jie SHAO ; Shaokang HUANG ; Yiping LUO ; Bingkun MENG ; Qunfei YU ; Yi ZHANG ; Wei LI ; Yushu BAI ; Ziqiang CHEN
Clinics in Orthopedic Surgery 2026;18(1):87-95
Background:
To investigate directional deviations between pilot holes and final pedicle screw trajectories in freehand placement and analyze risk factors for misplacement. While pedicle screws are widely used in thoracolumbosacral surgery, directional deviations between pilot holes and final screw trajectories remain understudied as potential risk factors for misplacement.
Methods:
Thirty-three patients undergoing posterior fixation were prospectively enrolled. Inertial measurement units (IMUs) tracked the spatial positions of pedicle finders and screwdrivers via custom software. Surgeons (n = 6) were stratified into senior, middle, and junior groups. Analyzed variables included the use of tapping, surgeon experience, spinal deformity status, screw tip morphology, and surgical parameters.
Results:
Among 198 implanted screws (6.00 ± 2.88/patient), all exhibited trajectory deviations (8.12° ± 3.47°). Tapping significantly reduced deviations (7.23° ± 3.23° vs. 8.87° ± 3.31°, p < 0.01). Senior surgeons achieved smaller deviations (7.34° ± 3.33°) than the middle group (8.60° ± 3.51°, p = 0.039) and junior group (8.68° ± 3.49°, p = 0.022). Multivariate analysis confirmed tapping (p = 0.001) and senior experience (p = 0.023) as protective factors. No significant associations emerged for spinal deformity (8.43° ± 3.73° vs. 7.97° ± 3.35°, p = 0.377), screw tip type (cylindrical, 8.43° ± 3.26° vs. tapered, 8.07 ± 3.51°; p = 0.637), obesity, or surgical position parameters.
Conclusions
Freehand pedicle screw placement consistently produces trajectory deviations from pilot holes, and surgeon experience and tapping are modifiable protective factors. The IMU-based tracking system enables quantitative surgical motion analysis, suggesting its utility for training optimization and technique standardization.
7.Spinal Needle-Guided Arthroscopic Transosseous Repair for Bony Bankart Lesions
Dongju SHIN ; Sung Hyuk PARK ; Kyoung Hwan KOH ; Sung CHOI
Clinics in Orthopedic Surgery 2026;18(1):184-188
Bony Bankart lesions present considerable challenges in shoulder surgery, particularly when large. While smaller lesions can often be treated effectively using the single-row technique, larger lesions require more complex approaches. Several arthroscopic techniques have been developed to manage these lesions. Although the double-row technique is effective, it has the disadvantage of placing suture material on the articular surface. In contrast, the transosseous technique permits adequate compression and surface contact without involving the articular surface; however, it is technically demanding and frequently requires specialized instruments. This technical note describes a simplified arthroscopic transosseous repair method for bony Bankart lesions using standard spinal needles and Kirschner wires, eliminating the need for specialized equipment while ensuring secure fixation and optimal surface contact.
8.Tibiotalocalcaneal Arthrodesis Using a Retrograde Intramedullary Nail without Subtalar Joint Preparation after Failed Total Ankle Arthroplasty
Yeo Kwon YOON ; Kwang Hwan PARK ; Dong Woo SHIM ; Seung Hwan HAN ; Jin Woo LEE
Clinics in Orthopedic Surgery 2026;18(1):151-158
Background:
Tibiotalocalcaneal (TTC) arthrodesis is a viable salvage option for failed total ankle arthroplasty (TAA), but it is typically a complex procedure associated with a high complication rate. This study analyzed outcomes of salvage TTC arthrodesis using a retrograde intramedullary (IM) nail without subtalar joint preparation after failed TAA.
Methods:
This study included 18 patients (18 ankles) who underwent TTC arthrodesis without subtalar joint preparation for failed TAA from July 2008 to March 2023 and were followed up for at least 2 years. Visual analog scale pain scores and Ankle Osteoarthritis Scale pain and disability scores were used to assess functional outcomes. Radiographic union, time to union, complications, and clinical success—defined as pain improvement without the need for revision surgery or amputation—were also evaluated.
Results:
The mean follow-up duration after TTC arthrodesis was 79.8 months (range, 26–199 months). Tibiotalar joint union was achieved in 13 ankles (72.2%) at a mean of 7.5 months after TTC arthrodesis. Subtalar joint union was achieved in 7 ankles (38.9%). All functional scores improved significantly from preoperatively to the last follow-up. The overall clinical success rate was 83.3% (15 ankles).
Conclusions
TTC arthrodesis using a retrograde IM nail without subtalar joint preparation produced favorable outcomes in patients with failed TAA. No complications associated with the subtalar joint were observed in any patient during follow-up. Therefore, TTC arthrodesis using a retrograde IM nail without subtalar joint preparation may be a considerable salvage option for failed TAA.
9.The Potentially Overlooked Dangers: Prevalence and Clinical Relevance of Incidental Extraspinal Findings on Cervical Spine Magnetic Resonance Imaging: A Retrospective Analysis of 2,286 Cases
Sung Jin SHIN ; Seung Myung WI
Clinics in Orthopedic Surgery 2026;18(1):63-70
Background:
Cervical spine magnetic resonance imaging (MRI) can reveal incidental extraspinal findings (IESFs) unrelated to the primary evaluation of cervical radiculopathy or myelopathy. Recognizing these lesions is crucial because some may require further investigation or treatment.
Methods:
We retrospectively reviewed 2,286 non-contrast cervical spine MRI scans performed between January 2019 and July 2024 in patients presenting with neck pain, shoulder pain, or neurological deficits suggestive of cervical radiculopathy or myelopathy. Patients with a history of malignancy, known head and neck tumors, or previous cervical surgeries were excluded. Boardcertified radiologists initially interpreted all scans. Documented IESFs were categorized into 5 groups: thyroid nodules, lymphadenopathy, soft-tissue tumors, brain lesions, and other head and neck lesions. Clinical follow-up data were analyzed to determine lesion outcomes. Statistical comparisons of demographics were performed using chi-square, t-test, and Mann-Whitney U-test.
Results:
IESFs were identified in 103 of 2,286 scans (4.5%). Thyroid nodules were the most common (n = 64, 2.0%), followed by lymphadenopathy (n = 16, 0.5%). Females had a higher incidence of IESFs than males (64.4% vs. 35.6%, p < 0.001), and the mean age was significantly higher in the IESF group (58.4 vs. 54.7 years, p = 0.033). Of 94 patients with available follow-up, 7 (7.4%) were confirmed malignant: 5 thyroid nodules and 2 lymphadenopathies. Two additional cases underwent surgery for pituitary and parathyroid adenomas. Four IESFs went unrecognized on initial review, underscoring the risk of missed diagnoses when the clinical workload is high.
Conclusions
IESFs in cervical spine MRI were detected in 4.5% of cases, with a notable subset being malignant. These findings emphasize the importance of systematic review protocols and interdisciplinary collaboration to ensure clinically significant lesions are identified and managed promptly.
10.Facet Effusion-Incorporating Grading System:A Modified Magnetic Resonance Imaging-Based Classification That Enhances Surgical Prognostication in Lumbar Foraminal Stenosis
Sung Taeck KIM ; Dong-Ho KANG ; Hyoungmin KIM ; Bong-Soon CHANG ; Jae Hun KIM ; Seonpyo JANG ; Jun-Yeop LEE ; Sam Yeol CHANG
Clinics in Orthopedic Surgery 2026;18(1):71-77
Background:
The conventional magnetic resonance imaging (MRI) grading system for foraminal stenosis (FS), known as the Lee classification, was introduced in 2010 and is widely utilized in clinical practice. Previous studies have reported that the conventional grading system for FS lacks prediction ability for surgical treatment. The purpose of this study was to develop a novel MRI grading system for lumbar FS with improved prediction ability for surgical treatment by incorporating facet effusion to indicate segmental instability.
Methods:
We retrospectively reviewed patients diagnosed with lumbar FS between 2011 and 2017 who had a follow-up period of at least 5 years. The FS severity was assessed using a conventional MRI grading system developed by Lee et al. We recorded whether the patient underwent surgical treatment for FS during the follow-up period and the time from the initial diagnosis to surgery. Survival analysis using a Kaplan-Meier curve and log-rank test was performed to verify the impact of FS severity on the surgical treatment. We performed additional survival analysis after modifying the grading system by incorporating the presence of excessive facet joint effusion assessed using axial MRI. We also compared the discrimination ability of the modified and conventional grading systems using Uno’s concordance index (C-index).
Results:
In total, 235 patients with a mean age of 63.7 years were included in this study. During the mean follow-up period of 8.1 years, 63 patients underwent surgical treatment for FS. The conventional grading system revealed no significant difference in survival between the grade 2 and 3 groups (p = 0.104). Conversely, the modified grading system revealed a significant difference in survival between the new grade 2 and 3 groups (p < 0.001). After modification, the discrimination ability, assessed using Uno’s Cindex, significantly improved from 0.69 to 0.73.
Conclusions
The Facet Effusion-Incorporating Grading System, which adds excessive facet joint effusion to the conventional MRI grading framework, demonstrated improved predictive value for surgical treatment and better discriminatory ability compared with the original system.

Result Analysis
Print
Save
E-mail