9.Experience on the factors affecting the accuracy of early gastrointestinal cancer pathological diagnosis
Chinese Journal of Clinical and Experimental Pathology 2025;41(3):281-284
The precision of pathological diagnosis for early gastrointestinal cancer is a critical determinant in the diagnosis and treatment of this condition.Several factors influence diagnostic precision.Based on clinical experience,the author highlights key aspects that require special attention in routine pathological diagnosis,including the standard-ized completion of pathological application forms,the representativeness and adequacy of biopsy,appropriate specimen handling,and pathologists'proficiency in the diagnostic criteria for early gastrointestinal cancer.Achieving precise pathological diagnosis of early gastrointestinal cancer necessitates adherence to the"full chain"approach,with close collaboration between endoscopists and pathologists at all stages of diagnosis and treatment,ultimately ensuring precise patient management.
10.Advances in pathological diagnosis and molecular characteristics of high-grade en-dometrial stromal sarcoma
Chinese Journal of Clinical and Experimental Pathology 2025;41(4):427-431
High-grade endometrial stromal sarcoma(HGESS)is a rare but highly aggressive malignant tumor that poses a significant threat to women's reproductive health.It is associated with a poor clinical prognosis due to its high malignancy.HGESS exhibits diverse pathological morphologies,lacks specific immunohistochemical markers,and demonstrates various genetic alterations.These factors contribute to the challenges in achieving a definitive diagnosis,making accurate identification and diagnosis of this lesion particularly difficult.This article reviews the clinicopathologi-cal features,molecular characteristics,and key points for differential diagnosis of HGESS,aiming to enhance under-standing and awareness of this disease among clinicians and pathologists.

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