Objective To explore the Lyophilizing Thrombin Powder combined with omeprazole in the treatment of peptic ulcer hemorrhage on clinical effect and influence on the change of the original level of the fiber protein.Methods118 cases of peptic ulcer bleeding from Yongkang Hospital were enrolled in this study, according to the order of hospitalization will be divided into observation group and control group.The control group were only given omeprazole and other conventional treatment;patients in the observation group was combined with Lyophilizing Thrombin Powder for treatment.The clinical treatment effect were compared between the two groups before and after treatment, compared two groups of patients with changes in fibrinogen levels.ResultsAfter treatment, the total efficiency rate of observation group was 91.07%, the total effective rate of control group was 75.81%, there was significant difference between two groups (P<0.05).Before treatment, two groups of patients with fibrinogen level was not statistically significant.With the treatment, the two groups of patients with fibrin the original level decreased, but the patients in the observation group decreased more significantly than the control group, the difference was statistically significant (P<0.05).ConclusionLyophilizing Thrombin Powder combined with omeprazole in the treatment of peptic ulcer bleeding effect significantly, can effectively reduce blood fibrinogen level, hemostasis, and its clinical use is safe and reliable, and is worth to popularize in clinic.

Objective To investigate the clinical effect of moxifloxacin combined with tinidazole and psychological intervention in the treatment of pelvic inflammatory disease. Methods The control group treated with moxifloxacin combined with tinidazole,pelvic inflammatory disease,the study group patients were given pelvic inflammatory tinidazole, moxifloxacin, combined with psychological intervention treatment (tinidazole and moxifloxacin administration methods and drug sources are the same as the control group). The clinical efficacy of two groups of pelvic inflammatory disease patients treated with 12 days was recorded. Results The group of patients with pelvic inflammatory disease were successfully completed corresponding treatment, the total effective rate of the study group was 95.65%, the control group was 68.18%, study group patients with pelvic inflammatory disease clinical curative effect was significantly better than the control group (P<0.05). Conclusion The application of moxifloxacin,tinidazole and psychological intervention in the treatment of pelvic inflammatory disease can significantly improve the clinical efficacy of patients, and is conducive to the protection of their quality of life, physical and mental health.

Objective To explore the basis of intracranial infection after craniocerebral operation with drainage combined with treatment in the application of vancomycin, meropenem and lumbar cistern on the use of psychological intervention clinical value. Methods 55 cases with intracranial infection craniocerebral injury patients were admitted to the Department of neurosurgery in Third Hospital of Jiaxing City in July 2012 to July 2017, the basic treatment in the application of drainage combined with vancomycin, meropenem and lumbar abroad, pay attention to the implementation of psychological nursing. Results The total effective rate of the group was 94.6%. Compared with before treatment, the number of WBC and protein in CSF decreased significantly, and the level of glucose increased significantly, with statistical difference (P<0.05). Compared with the intervention, the psychological status score improved obviously after intervention, with statistical difference (P<0.05). Conclusion The patients with craniocerebral injury complicated with intracranial infection after operation, basic drainage combined with treatment in application of meropenem and vancomycin, lumbar cistern on the use of psychological nursing, can improve the total clinical efficiency, improve psychological status.

Objective To investigate and analyze the effect of psychological intervention and insulin treatment on anxiety in elderly patients with diabetes mellitus. Methods 92 elderly patients with diabetes mellitus from January 2016 to January 2017 in the first affiliated hospital of Wenzhou medical university chengdu campus were randomly divided into the control group and the experimental group, 46 patients for each group. The control group was treated with conventional insulin therapy, the experimental group was given psychological intervention on the basis of the control group, strengthened communication and exchanges, increased confidence. The anxiety levels of two groups were compared and analyzed. Results After treatment, 46cases were satisfied in the experimental group, and 40 cases were satisfied in the control group. The satisfaction degree of nursing in the control group was 86.96%, significantly lower than 100.00% in the experimental group, which was statistically significance (P<0.05). After the intervention, the HAMA score of the experimental group was (10.54±5.40), significantly lower than (14.63±5.23) of the control group with statistical significance (P<0.05). Conclusion The application of psychological intervention combined with insulin treatment in elderly patients with diabetes could significantly improve the anxiety and the satisfaction of nursing, and has the significance of clinical promotion.

Objective To investigate the effect of psychological intervention, Plavix, Aspirin Enteric-coated Tablets combined in the treatment of non ST segment elevation acute myocardial infarction. Methods 102 patients with non ST elevation acute myocardial infarction were selected in Taizhou Central Hospital from January 2015 to January 2017 and divided into study group (n=51) and control group (n=51) by single and double number (hospital admission order) method. The control group were treated with clopidogrel, Aspirin Enteric-coated Tablets, the study group on the basis of routine treatment, were given plavix, Aspirin Enteric-coated Tablets, comprehensive psychological intervention program. Results The total effective rate of the study group was 90.20%, and the total effective rate of the control group was only 70.59%, the difference was statistically significant (P<0.05). Conclusion The application of psychological intervention combined with plavix, Aspirin Enteric-coated Tablets treatment of non ST elevation acute myocardial infarction can significantly improve the clinical efficacy, to ensure the quality of life, life is of positive significance to safety.

Objective To study the Hengkangzhengqing combined application of psychological intervention in the bowel preparation before colonoscopy. Methods 400 cases of colonoscopy patients from January 2016 to December 2016 were selected and randomly divided into the control group and the experimental group, each with 200 cases. The control group were treated with Hengkangzhengqing, experimental group on the basis of psychological intervention on the mental status of patients and patients, strengthen communication and exchanges, increase the treatment compliance of patients. Comparative analysis of the two groups of patients related clinical indicators. Results In the control group, 100 cases of intestinal cleaning efficacy of 0 scores, and 80 cases of 1 scores. In the experimental group, 80 cases had clean bowel effect, and 70 cases were 1 scores. The intestinal cleaning effect of the experimental group was 90.0%, the percentage of the control group 0~1 scores was 75.0%, and the intestinal cleaning effect of the experimental group was significantly better than that of the control group, with statistical significance (P<0.05) (0-1 scores). The adverse reaction rate in the experimental group was 8.0%, significantly lower than that in the control group (22.0%), with statistical significance (P<0.05). In the control group, 80 cases received excellent bowel preparation, and 70 cases were good. In the experimental group, 110 patients received excellent intestinal preparation and 82 patients were good, the excellent rate of the 2 groups was statistically significant (P<0.05). Conclusion Hengkangzhengqing combined with psychological intervention in a safe colonoscopy application in bowel preparation, can significantly improve the cleaning effect and acceptability, has clinical significance.

Objective To study the clinical treatment effect of intraoperative perfusion of Panax notoginseng saponins on the postoperative mammary gland hematoma and skin ecchymosis. Methods A total of 100 patients who underwent breast minimally invasive surgery from August 2015 to May 2016 in Wenling First People's Hospital were randomly divided into control group and experimental group 50 cases in each group.The control group underwent intraoperative perfusion of Panax notoginseng saponin,on the basis of this, the experimental group were given psychological intervention, pay attention to the psychological state of the patients, strengthen the communication and exchanges with the patients, increased the patient's treatment confidence and treatment compliance. The clinical indicators of the experimental group and the control group were compared. Results After the corresponding treatment, the incidence of postoperative hematoma in the experimental group (4.0%) was significantly lower than in the control group (12.0%), the difference was statistically significant (P<0.05). The probability of skin staining in control group (26.0%) was significantly higher than that in the experimental group (8.0%), the difference was statistically significant (P<0.05). Conclusion Breast minimally invasive biopsy perioperative psychological intervention, intraoperative perfusion of panax notoginseng saponins can reduce the incidence of postoperative mammary gland hematoma, skin ecchymosis.

Objective To study the clinical efficacy of low dose thyroxine combined with irbesartan hydrochlorothiazide in the treatment of elderly patients with severe heart failure. Methods 60 cases of elderly patients with severe heart failure who were admitted from January 2015 to December 2016 were selected as the research object in this study. They were randomly divided into control group and experimental group, each group was divided into two groups, each with a total of 30 cases. Patients in the control group were treated with conventional therapy, while the experimental group was treated with low dose thyroxine combined with irbesartan and hydrochlorothiazide. Comparative analysis of clinical efficacy of the experimental group and control group. Results After treatment, the total effective number of patients in the experimental group was 26 cases, the effective rate was 86.7%. The total effective number of patients in the control group was 21 cases, the effective rate was 70.0%. Therefore, the effective rate of the experimental group was significantly higher than that of the control group, with statistical difference (P<0.05). After treatment, the experimental group of patients with left ventricular ejection fraction index, four triiodothyronine and three triiodothyronine levels were significantly higher than those before treatment, the control group of patients with left ventricular ejection fraction were significantly higher than before treatment, with statistical difference (P<0.05). Conclusion Low dose thyroxine combined with irbesartan hydrochlorothiazide in the treatment of elderly patients with severe heart failure has better clinical effect, can improve the therapeutic effect in a certain extent, with further clinical promotion and application significance.intervention in two groups. Results The clinical intervention effect of the observation group was better than that of the control group, the stability of the tumor focus, the degree of pain, the quality of life and other aspects were better than the control group, the difference between the two groups was statistically significant (P<0.05). Conclusion Patients with advanced non-smal cell lung cancer chemotherapy choose psychological intervention compound sophora injection combined treatment effect is remarkable, which can effectively improve the patient's clinical symptoms and quality of life.

Objective To analyze the effect of Yishenkang capsule on urinary protein in patients with chronic glomerulonephritis uraemia. Methods 100 patients with chronic glomerulonephritis uraemia from March 2013 to April 2016 were divided into two groups with lottery method and 50 cases for each group. Two groups were treated with dialysis and routine treatment, the treatment group was added Yishenkang capsule to analyze its effect. Results After treatment, 24 h urinary protein of two groups decreased than before treatment, both Alb and Hb increased than before treatment, and the treatment group was better than that of the control group with statistical significance (P<0.05). SCr, BUN and UA level of two groups decreased than before treatment, the treatment group was lower than that of the control group with statistical significance (P<0.05). The level of inflammation in the control group was significantly higher than that before treatment, the treatment group decreased and lower than that of the control group with statistical significance (P<0.05). There were no significant differences in adverse reactions between two groups. Conclusion Yishenkang capsule could decrease the excretion of urine protein in patients with chronic nephritis uraemia, improve the renal function and has few adverse reactions.

Objective To analyze clinical effects of Mupirocin ointment combined with topical glucocorticoid drugs in treating eczema/atopic dermatitis. Methods 100 patients with eczema / atopic dermatitis patients treated in our hospital from March 2015 to August 2016 were selected and randomly divided into the control group and the experimental group, 50 patients in each group. The control group were treated with glucocorticoid therapy, the experimental group were treated with topical corticosteroids combined with Mupirocin ointment drug. Compared the clinical effect between two groups. Results After treatment, 7 cases relapsed in the experimental group and 17 relapsed in the control group.The recurrence rate of the control group(34.0%)was significantly higher than that of the experimental group (14.0%),there was significantly statistical difference(P<0.05). There were no obvious adverse reactions in two groups. In the experimental group, 8 cases were ineffective, and the total effective number was 42 cases. In the control group, 20 cases were ineffective, and the total effective number was 30 cases. The effective rate of the control group (60.0%) was significantly lower than that of the experimental group(84.0%), there was significantly statistical difference (P<0.05). Conclusion Mupirocin ointment combined with topical glucocorticoid drugs was good clinical effect and low adverse reactions.