Objective To investigate the clinical effect of Walit on central serous retinopathy. Methods A total of 92 patients with central serous retinal retinopathy were enrolled in our hospital from January 2015 to January 2017, and were randomly divided into control group and study group (n=46). The control group, the central serous chorioretinopathy treated with laser therapy, the study group by laser combined with Walit therapy, two groups were treated for 4 weeks, the curative effect and follow-up records, the data input SPSS software. Results The two groups of central serous chorioretinopathy patients successfully completed the treatment. The study group central serous chorioretinopathy in patients with clinical therapy in the treatment of the total efficiency (91.30 %) was significantly better than the control group (76.09 %), the differences were statistically significant (P<0.05); recurrence rate of study group (0.00 %) was significantly lower than the control group (13.04 %), the differences were statistically significant (P<0.05). Conclusion The use of laser treatment for central serous chorioretinopathy combined with Wolitingke significantly improve curative effect, has the positive significance to guarantee the prognosis and quality of life.

Objective To investigate the clinical effect of compound lidocaine cream in the supine position of the department of orthopedics under general anesthesia of laryngeal mask airway. Methods 100 cases of laryngeal mask intubation under general anesthesia for department of orthopedics supine internal fixation surgery patients as the research object, are in our hospital from February 2016 to February 2017 were randomly divided into liquid, paraffin oil lubrication for anesthesia (control group, n = 50) with compound lidocaine anesthesia for emulsion lubrication (observation group, n = 50) contrast effect. Results Compared with the control group, the 0-3 stage agitation rate, language instruction satisfaction, laryngeal mask extraction time and complications were better in the observation group (P<0.05). Conclusion The laryngeal mask anesthesia department of orthopedics fixation removal patients, application of compound lidocaine cream hood to daub lubricating anesthesia on agitation for effective control, to improve the language instruction with satisfaction, shorten the extraction time of laryngeal mask, lower complication rate.

Objective To study the efficacy of azithromycin in the treatment of acute bronchitis. Methods The 300 patients with acute bronchitis treated by our hospital from August 2016 to February 2017 were randomly divided into the control group and the experimental group, each with 150 patients. The control group was treated with penicillin and azithromycin was treated by the experimental group. Comparative analysis was made on the clinical indicators of the experimental group and the control group. Results After the corresponding treatment, the improvement time of cough sputum in the experimental group was (4.19 ± 0.54), and the improvement time was (4.32 ± 0.65). The improvement time of cough sputum in the control group was (6.29 ± 0.87), and the improvement of pharyngeal pain was (5.32 ± 0.76) days. However, the improvement time of cough expectorus and pharyngeal pain in the experimental group was significantly shorter than the control group, the differences were statistically significant (P＜0.05). Of the patients in the experimental group, 6 patients were not effective, 14 patients improved, 70 patients showed positive results and 60 patients recovered. In the control group, the total number of cases was 110, 15 were invalid, 25 were improved, 60 were developed and 50 were cured. However, the efficiency of the experimental group was 86.67 %, significantly higher than that in the control group (73.33 %), the differences were statistically significant (P＜0.05). The clinical recovery time of the patients in the experimental group was (5.65±1.19), which was significantly shorter than that of the control group (6.89±1.46), the differences were statistically significant (P＜0.05). Conclusion The clinical efficacy of azithromycin in the treatment of acute bronchitis is better, which can significantly improve the treatment efficiency, relieve the patient’s related symptoms, and have the significance of clinical promotion.

Objective To study clinical effects of the fexofenadine hydrochloride Tablets and BCG-PSN in the treatment of chronic urticaria. Methods 122 patients with chronic urticaria treated in Yiwu skin disease hospital from January 2016 to March 2017 were selected and randomly divided into the control group and the experimental group, 61 patients for each group. The control group was given Fexofenadine Hydrochloride Tablets treatment, the experimental group was given BCG-PSN on the basic treatment of the control group. The patients in the experimental group and the control group were treated for 3 months. The treatment effect and adverse reactions were compared between two groups. Results After the corresponding treatment, the number of invalid cases in the experimental group was 10. In the control group, 21 cases were ineffective. The effective rate of the experimental group was 63.93%, which was significantly higher than 32.97% of the control group with statistical significance (P<0.05). There were no obvious adverse reactions in the two groups, and there was no significant difference in the incidence of adverse reactions. After treatment, the integral score of the experimental group was (3.20±0.42), significantly lower than that of the control group (3.98±0.37), with statistical significance (P<0.05). Conclusion fexofenadine hydrochloride Tablets combined with BCG-PSN for the treatment of chronic urticaria could significantly improve clinical symptoms of patients with good efficacy, high safety and clinical application significance.

Objective To observe the clinical effect of acute angina pectoris in cardiovascular surgery. Methods 92 patients with acute angina were enrolled in our hospital from March 20 to March 2017 were randomly divided into study group and control group,with 46 cases in each group. The control group was treated with enalapril and aspirin enteric-coated tablets. The study group was treated with clopidogrel on the basis of the control group.The clinical effect of the two groups after treatment was observed, and the incidence, duration and total effective rate of acute angina were compared between the two groups. Results The incidence of acute angina pectoris and pain time in the study group were significantly lower than in the control group (P<0.05). The total effective rate of the treatment group was significantly higher than that of the control group (P<0.05). Conclusion The combination of enalapril, aspirin enteric-coated tablets and clopidogrel in patients with acute angina pectoris can effectively reduce the number of acute angina pectoris and shorten the duration of onset of pain. The clinical effect is significant and high clinical application value.

Objective To study and analyze of clinical effect of Kangfuxin liquid combined with traditional Chinese medicine enema in the treatment of radiation enteritis. Methods 120 cases of radiation enteritis caused by radiotherapy in the affiliated hospital of Southwest medical University from February 2015 to August 2016 were selected as the research objects. They were randomly divided into the control group and the experimental group, 60 cases for each group. The control group was given 100mL saline and 10mg dexamethasone enema treatment. The patients in the experimental group were given Kangfuxin liquid combined with Traditional Chinese Medicine enema treatment, two groups of patients were treated for 4 weeks. The therapeutic effects of the two groups were compared and analyzed. Results In the experimental group, 6 patients were cured, 34 cases were improved, 20 cases were cured. In the control group, 21 patients were cured, 23 cases were improved, 16 cases were cured. The effective rate of treatment in the experimental group was 90.0%, which was significantly higher than that in the control group, and the effective rate was 65.0%, with statistical difference (P<0.05). There were no obvious adverse reactions in the experimental group and the control group. The average hospital stay in the control group was (30.98±2.10) d, significantly longer than the experimental group, the average length of stay (23.89±2.31) d, with statistical difference (P<0.05). Conclusion Kangfuxin liquid combined with Traditional Chinese Medicine enema in the treatment of the has good clinical effect in treating radiation enteritis, and high effective rate of treatment of radiation enteritis with high safety.

Objective To investigate influence of combined use of allopurinol and warfarin on the INR of chronic permanent atrial fibrillation hyperuricemia patients. Methods 80 cases of patients with chronic atrial fibrillation complicated with hyperuricemia, in Sanmen County People's Hospital from February 2016 to February 2017 were randomly divided into the control group (n=40) and the observation group (n=40), the control group was given warfarin plus low purine diet treatment, the observation group was given additional Allopurinol treatment. Changes of INR were compared. Results There was no statistical significance in INR level before treatment between the two groups of patients with permanent atrial fibrillation complicated with chronic hyperuricemia. The INR level of the control group was not changed after treatment, the observation group increased significantly after treatment, and there was statistical significance between the two groups (P<0.05). There were no bleeding events in the control group, there were 6 cases of the observation group with minor bleeding and subcutaneous ecchymosis, including 2 cases with fecal occult blood, 1 cases with hematuria, nasal hemorrhage . The change of liver and kidney function was not obvious. Conclusion In application of allopurinol treatment plus warfarin for patients with chronic persistent atrial fibrillation and hyperuricemia patients, , INR need to be regularly monitored, in order to provide reference for Warfarin dosage adjustment, and ensure clinical safety.

Objective To investigate the therapeutic effect of cefradine on lobar pneumonia and its influence on the prognosis of patients with lobar pneumonia. Methods 90 cases of lobar pneumonia patients from December 2015 to May 2017 were randomly divided into the study group and the control group, with 45 cases in each group. The study group was treated with latamoxef on the basis of routine treatment, the control group was treated with cefoperazone on the basis of routine treatment ,recorded in two groups after 2 weeks of treatment. The clinical efficacy,drug related adverse reactions occur of the two groups were recorded after two weeks of treatment. Results The total effective rate in the study group(93.33%) was significantly higher than that of the control group(73.33%)(P<0.05). There was no significant difference in the incidence of drug-related adverse reactions between the two groups during the treatment period. Conclusion The application of latamoxet in the treatment of lobar pneumonia can significantly improve the clinical efficacy of patients, and is conducive to the protection of their prognosis and quality of life.

Objective To compare the clinical efficacy and safety of docetaxel combined with carboplatin (TP) and epirubicin combined with cyclophosphamide sequential docetaxel (EC-T) adjuvant in the treatment of three negative breast cancer in phase III . Methods 62 cases of three negative breast cancer patients in phase III from May 2012 to October 2016 were selected and randomly divided into the control group and the experimental group, with 31 patients in each group. The control group was treated with epirubicin combined with cyclophosphamide and sequential docetaxel, and the experimental group was treated with docetaxel and carboplatin. The clinical indicators were compared and analyzed. Results There was no significant difference in the recent remission rate (77.42%) between the experimental group and the control group (74.19%). Two groups of patients with adverse reactions were restored within one month. There were 10 cases of WBC decrease in the experimental group, with the incidence rate of 32.25%. There were 18 cases of WBC decrease in the control group, the incidence rate was 58.06%, the difference was statistically significant (P<0.05). Conclusion Docetaxel combined with carboplatin and epirubicin adjuvant combined with cyclophosphamide than star sequential docetaxel in the treatment of three patients with negative breast cancer stage III were tolerated, TP occurred leukopenia and alopecia with low probability.

Objective To investigate the effect and safety of Gukang capsule combined with sodium hyaluronate injection on the treatment of the patients with osteoarthritis. Methods 94 osteoarthritis patients selected from December 2015 to March 2017 were randomly divided into study group (n=47) and control group (n=47). The control group were given sodium hyaluronate injection, the study group were received local injection of sodium hyaluronate combined with Gukang capsule. The changes of knee joint function (HSS scale score) and adverse reaction rate were recorded and compared before and after treatment in the two groups. Results Before treatment, there was no significant difference in HSS scores between the two groups. After treatment, the HSS score in the study group was significantly better than that in the control group (P<0.05). There were no significant differences in the adverse reactions between the 2 groups during the treatment. Conclusion Local injection of sodium hyaluronate combined with Gukang capsule on the treatment of osteoarthritis, which can significantly improve the clinical efficacy, the security is higher. .