Objective To study the value of video EEG combined with MRI in the diagnosis of intractable epilepsy.Methods40 patients with intractable epilepsy treated in our hospital from 2013 to 2015 were selected as the subjects.In 40 patients, 26 patients with hippocampal sclerosis, 2 cases of patients with temporal lobe atrophy with cerebral dysplasia, 4 cases of patients with cerebral gray matter and macrogyria, 3 cases of vascular malformation, 1 cases of patients with intracerebral cyst, 2 cases of patients with glioma, 2 cases of patients with traumatic epilepsy.Retrospective of The clinical data of the selected patients were analyzed and the manifestations of epileptic foci were reflected by MRI, The use of video EEG was used to detect the status and source of EEG during epileptic seizure and epilepsy Analysis, combined with MRI scan and video EEG results, control surgery pathological changes, analysis of the results, draw conclusions.ResultsThere were 21 cases of the accurate location of interictal EEG.The accuracy was 52.5%, and the accuracy of the location of epileptogenic foci was about 40, and the accuracy was about 100%.The accuracy of MRI in the diagnosis of epileptic foci and related lesions was 35 cases, the accuracy rate was 87.5%, and the number of lesions was qualitative and accurate in the case of 30 cases, with an accuracy rate of 75%.ConclusionVideo EEG combined with MRI examination for drug refractory epilepsy diagnosis has important clinical value, can make a more accurate diagnosis of patients with epileptogenic foci, provide information for surgical treatment of intractable epilepsy patients, with further clinical promotion and application significance.

Objective To explore the effect of psychological intervention combined with drug multimodal treatment on analgesic effect and stress reaction in Department of orthopedics.Methods80 cases of Department of orthopedics patients in Ruian City People's Hospital from March 2016 to March 2017 were selected and randomly divided into control group and observation group, 40 cases in each group.The control group was treated with drugs only, and the observation group was treated with psychological intervention combined with multi multimodal.The analgesic effect and stress response of the 2 groups were observed.ResultsThe satisfaction rate in observation group were significantly higher than the control group.There was no significant difference in heart rate, diastolic blood pressure and systolic blood pressure between two groups before intervention, after group intervention, the changs in observation group were relatively small, and the difference was statistically significant(P<0.05).Visual acupuncture scores were observed at different time points,the pain in the observation group was significantly lower than that in the control group, the difference was statistically significant (P<0.05).ConclusionMultimodal therapy for analgesia in the Department of orthopedics and found psychological intervention combined with stress reaction the drug, compared with simple drug intervention, can play a good analgesic effect, at the same time to reduce the patient's stress response, so it is worthy of reference.

Objective To study the clinical diagnostic value of MCV, MCH and RDW in children with iron deficiency anemia.Methods40 cases of children with iron deficiency anemia in our hospital from May 2014 to May 2016, were selected as iron deficiency anemia group, another 40 healthy children were chosen in our hospital underwent the healthy control group, using imported reagent in 2h in the MCV, MCH and RDW index value is read out, and then the children of the two groups of MCV, MCH and RDW values were statistically analyzed.ResultsThe levels of iron, and zinc in children with iron deficiency anemia were significantly lower than those in healthy control group (P<0.05), but there was no significant difference in copper, calcium and magnesium levels between the two groups;The MCV and MCH values of children with iron deficiency anemia group were significantly lower than those in healthy control group (P<0.05),the RDW value was significantly higher than that in healthy control group (P<0.05).ConclusionMCV, MCH and RDW detection for clinical diagnosis of iron deficiency anemia in children is high, can be an effective basis for clinical prevention and early diagnosis and treatment of iron deficiency anemia in children, it is worthy of clinical application.

Objective To study the interference and influence of blood specimen hemolysis in biochemical test results.Methods80 cases of personnel received physical examination in our hospital from May 2014 to May 2016 were selected, these personnel were divided into hemolytic group (n=40) and non hemolytic group (n=40) on the basis of blood specimen hemolysis occurred situations, 5mL morning fasting venous blood of the two groups was collected, they were placed in heparinized tubes, the blood of the hemolytic group was stirred by bamboo inducing hemolysis;The blood of the non hemolysis group was without the above treatment, directly at the rate 2500r/min 10min centrifugal separating serum, the K+, GLU, ALB, TP, CK, TBIL, BUN, ALT, AST, LDH levels of the two groups were detected by automatic biochemical reaction analyzer, and then the biochemical indicators levels of the two groups were statistically analyzed.ResultsThe level of GLU in the hemolysis group was significantly lower than that in the non hemolytic group (P<0.05), the K+, TP, CK, TBIL, AST, LDH levels in the hemolysis group were significantly higher than those in the non hemolytic group (P<0.05), but the differences of ALB, BUN, ALT levels between the two groups were not significant.ConclusionBlood specimen hemolysis can interfere and influence the biochemical tests results to some extent.

Objective To investigate the effect of acupoint massage on vital signs in patients undergoing percutaneous coronary intervention surgery.Methods128 patients underwent percutaneous coronary intervention surgery from January 2014 to June 2016 were divided into the observation group and the control group according to the random number table, 64 cases in each group.The control group were given traditional surgery,and received routine treatment at postoperative rehabilitation period.At the basis of this, the observation group were given acupoint massage.The liver and kidney function indexes, coagulation function, blood routine, heart rate and blood pressure in the two groups were compared.ResultsThe systolic blood pressure was (142.98±18.35mmHg, the diastolic blood pressure was (92.83±17.28) mmHg and the heart rate was (79.4±11.7) times/min in the observation group;the systolic blood pressure was (143.26±17.26) mmHg, the diastolic blood pressure was (82.65 ± 13.17) mmHg and the heart rate was (71.9±12.1) times/min in the control group, the differences in the two groups was statistically significant(P<0.05).The TBIL of the control group was (9.36±3.71)umol·L-1, DBIL was (4.01±1.14)umol·L-1, TP was (53.23±7.29) g·L-1, and the difference was statistically significant (P<0.05, ALB was (32.10±3.17) g·L-1 and BUN was (4.23 ± 1.32) mmol·L-1, which was lower than that of TBIL, DBIL, TP and ALB in the observation group (P<0.05) The levels of PTA and FIB in the observation group were higher than those in the control group.The levels of PT, APTT and TT were lower than those in the control group, the difference was statistically significant (P<0.05).ConclusionAcupoint massage can effectively enhance the liver and kidney function and coagulation function, reduce the blood pressure and heart rate of patients, relieve anxiety and reduce the recovery time of patients.

Objective To explore the effect of the contrast frame mirror and the corneal contact lens correction on the optical properties of the human eye.Methods120 cases of myopia patients from 2014 September to September 2015 in our hospital for vision correction were randomly divided into two groups: control group, observation group wearing frame mirror, wearing contact lens, the optical properties of the eye were compared between the two groups.ResultsThe corrected visual acuity of observation group hadno significant difference compared with the control group;no significant difference in the values of refractive foveal contrast;foveal refractive value contrast in the two groups had no statistical difference;the observation group T30 degrees for peripheral refraction was (1.00±0.21) D, N30°peripheralrefraction was (0.34±0.08) D,were significantly lower than the control group (P<0.05).The good rate of observation group was significantly higher than the control group, the incidence of corneal complications was significantly lower than that of the control group (P<0.05).ConclusionThe frame and the corneal contact lens can be well corrected visual acuity, the corneal contact lens for the correction of certain peripheral hyperopic defocus has advantages, can effectively reduce the peripheral hyperopic defocus, delaying myopia, and improve the comfort and safety.

Objective To explore the distribution of pathogens in lower respiratory tract infection, and to explore the drug resistance, and summarize the clinical experience.MethodsFrom February 2014 to August 2016 in Changxing county people's hospital, the specimens of the patients with lower respiratory tract infection were analyzed.Distribution of pathogenic bacteria was analyzed and its drug resistance was summarized.ResultsA total of 100 strains of bacteria were isolated, including 27(27%) strains of fungi, 26(26%) strains of gram positive bacteria, 47(47%) strains of gram negative bacteria.The proportion of gram negative bacteria was significantly higher than that of gram positive bacteria and fungi, and the difference was statistically significant (P<0.05).Different pathogenic bacteria have different drug resistance to commonly used antibiotics.The resistance of Candida albicans to fluconazole was 100.0%, the resistance of Staphylococcus aureus to compound sulfamethoxazole was 90% and to gentamicin was 100.0%, the resistance of Escherichia coli to levofloxacin was 100.0%.ConclusionGram negative bacteria accounted for the highest proportion in pathogen of lower respiratory tract infection.Different pathogenic bacteria have different resistance to different antibiotics in clinical, and monitoring and rational use of drugs should be strengthened in order to improve the efficacy and reduce drug resistance.

Objective To explore the airway management strategy of patients with double-lumen tracheal intubation during anesthesia recovery period.MethodsA retrospective analysis of clinical data of 60 patients who underwent double-lumen tracheal intubation were enrolled from december 2014 to december 2016 in oue hospital was conducted.The mean arterial pressure (MAP), blood oxygen saturation (SpO2), heart rate (HR) and respiration (R) of all patients were measured at different time points,before and after operation, before and after extubation.ResultsThere was no significant difference in MAP and SpO2 between before and after operation,the levels of MAP and SpO2 before extubation and in extubation were significantly higher than those before operation (P<0.05), and five to ten minutes after extubation returned to the preoperative level.There was no significant difference in HR and R indexes between before and after operation, and the HR and R indexes in extubation and before extubation were significantly higher than those before operation, the difference was statistically significant(P<0.05), which was returned to preoperative level ten minutes after extubation.ConclusionIn the patients with double-lumen tracheal intubation, the observation and scientific care of the airway in the recovery period of anesthesia can not only ensure the stability of the vital signs, but also improve the safety of the patients.It is worthy of clinical application.

Objective To investigate the pathogen distribution and drug resistance of biliary tract infection in patients with cholelithiasis, and to summarize the clinical experience.Methods160 patients with cholelithiasis were analyzed.The proportion of patients with biliary tract infection was counted.The bile and venous blood were collected and the distribution of pathogens was detected.The patients were also analyzed for the drug resistance.ResultsThe incidence of biliary tract infection was 62.5%, the positive rate of bile culture was 62.5%, and the positive rate of blood test was 37.5% for 160 patients with cholelithiasis.Gram-positive bacteria include Escherichia coli, Enterococcus faecium, Staphylococcus, Gram-negative bacteria, including Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, etc.;Gram-positive bacteria for the large Methicillin and erythromycin resistance is higher, Gram-negative bacteria for ampicillin and levofloxacin higher resistance.ConclusionThe pathogen distribution and drug resistance of biliary tract infection in patients with cholelithiasis are analyzed.The clinical pathogens are widely distributed.At the same time, the pathogens have different resistance to different antimicrobial agents.Therefore, clinical use should be reasonable choice when using antimicrobial agents, With a view to give full play to drug effects.

Objective to investigate the effects of alprostadil on the levels of UAER, SCr, TNF-alpha and hs-CRP in patients with diabetic nephropathy (DN).Methods110 cases with DN from January 2014 to December 2015 in Dagang hospital Tianjin Binhai New Areawere randomly divided into the alprostadil group(basic treatment+alprostadil) and the control group (basic treatment), 55 cases in each group.The clinical effect and the indexes of inflammatory reaction and oxidative stress were compared in the two groups.ResultsAfter treatment, UAER, 24h urinary protein, serum MDA, 8-OHdG, TNF-α, IL-18, ICAM-1, hs-CRP in the alprostadil group were lower than those in the control group (P<0.05);serum SOD, GSH-Px levels in the alprostadil group were higher than those in the control group (P<0.05).The total effective rate of diabetic nephropathy in alprostadil group (92.73%) was significantly higher than that in control group (74.55%), the data were compared with(P<0.05).ConclusionIt has a positive effect on improving the therapeutic effect which alprostadil in the treatment of patients with DN, and it can relieve the inflammatory reaction and oxidative stress injury.