1.Observation on the effect of psychological intervention of iron combined with erythropoietin in the treatment of anemia in hemodialysis patients
Xi'er HE ; Yan-qin DING ;
Chinese Journal of Biochemical Pharmaceutics 2017;37(8):262-263,266
Objective And effect of psychological intervention observation and analysis of iron combined with erythropoietin in the treatment of anemia in hemodialysis patients and the effect of. Methods 110 cases of Shaoxing Hospital of Traditional Chinese Medicine in anemic hemodialysis patients with January 2015 to February 2016 underwent diagnosis and treatment as the research object of the study, all the patients were randomly divided into 2 groups, respectively for the test group and control group, 2 groups of 55 cases. The control group was treated with erythropoietin receptor activator and psychological intervention treatment, experimental group was treated with ferrous succinate combined with erythropoietin receptor activator for treatment, but also psychological nursing intervention, observation and comparison of the symptoms of anemia, 2 groups of patients after treatment of adverse reaction etc. Results The experimental group patients with red blood cells, serum ferritin, hemoglobin and hematocrit were significantly higher than control group, the difference was statistically significant (P<0.05); side effects in test group than in the control group, the difference was statistically significant (P<0.05). Conclusion Iron combined with erythropoietin treatment in anemic hemodialysis was more effective at the same time, then the implementation of the corresponding psychological intervention, can reduce the adverse reactions in patients with symptoms, improve the safety of the treatment, and has high applicationvalue.
2.Efficacy and safety of low molecular weight heparin combined with aspirin and urokinase in the treatment of acute myocardial infarction
Zabeer tan Gulistan ; immortals A-yi
Chinese Journal of Biochemical Pharmaceutics 2017;37(5):382-384
Objective To investigate the efficacy and safety of low molecular weight heparin combined with aspirin and urokinase in the treatment of acute myocardial infarction.MethodsEighty patients with acute myocardial infarction were randomly divided into control group and observation group.Forty patients in the first affiliated hospital of Xinjiang Medical University from January 2013 to January 2016 were randomly divided into control group and observation group.Forty patients were treated with low molecular weight heparin combined with enteric-coated aspirin;Observation group in the control group based on intravenous thrombolytic therapy.The changes of blood vessel recanalization rate, serum factor level, treatment effect and complication were observed and compared.ResultsThe levels of serum IL-6, IL-8, IL-10 and HSP70 in the two groups were significantly lower than those in the control group (P<0.05).The postoperative complications and acute mortality were significantly lower in the observation group than in the control group (P<0.05).ConclusionLow molecular weight heparin combined with aspirin and urokinase in the treatment of acute myocardial infarction can effectively improve the rate of coronary artery opening, reduce the incidence of complications, safe and reliable, worthy of clinical promotion.
3.Clinical analysis of serotretine combined with metformin in the treatment of senile diabetic patients with sulfonylurea failure
Chinese Journal of Biochemical Pharmaceutics 2017;37(7):296-298
Objective To investigate the clinical effect of sitagliptin combined with metformin in the treatment of sulfonylurea-deficient elderly patients with diabetes mellitus.Methods Sixty patients with diabetes mellitus were enrolled in our hospital from January 2013 to December 2016.The patients were divided into observation group(30 cases) and control group(30 cases) according to the random number method.The patients in the observation group were treated with sitagliptin and metformin.The patients in the control group were treated with gemcitabine, and the clinical treatment effect, fasting blood glucose, postprandial blood glucose, glycosylated hemoglobin, fasting C peptide and postprandial 2hC peptide Level of statistical comparison.Results The clinical effect of the observation group was significantly higher than that of the control group.Before and after treatment, the fasting blood glucose, 2h postprandial blood glucose, glycosylated hemoglobin, fasting C peptide and postprandial 2hC peptide level were not significantly different After fasting blood glucose, 2h postprandial blood glucose and glycosylated hemoglobin levels were significantly lower than before treatment, after treatment of fasting C peptide and postprandial 2hC peptide levels were significantly higher than before treatment.Conclusion The clinical efficacy of serotretine combined with metformin in the treatment of elderly patients with diabetes mellitus is similar to that of Yuxing, and the combination is more convenient and more suitable for clinical treatment.It is worthy to be popularized and applied in clinical practice.
4.Effects of moxifloxacin,tinidazole and psychological intervention on pelvic in terrention
Chinese Journal of Biochemical Pharmaceutics 2017;37(10):282-283
Objective To investigate the clinical effect of moxifloxacin combined with tinidazole and psychological intervention in the treatment of pelvic inflammatory disease. Methods The control group treated with moxifloxacin combined with tinidazole,pelvic inflammatory disease,the study group patients were given pelvic inflammatory tinidazole, moxifloxacin, combined with psychological intervention treatment (tinidazole and moxifloxacin administration methods and drug sources are the same as the control group). The clinical efficacy of two groups of pelvic inflammatory disease patients treated with 12 days was recorded. Results The group of patients with pelvic inflammatory disease were successfully completed corresponding treatment, the total effective rate of the study group was 95.65%, the control group was 68.18%, study group patients with pelvic inflammatory disease clinical curative effect was significantly better than the control group (P<0.05). Conclusion The application of moxifloxacin,tinidazole and psychological intervention in the treatment of pelvic inflammatory disease can significantly improve the clinical efficacy of patients, and is conducive to the protection of their quality of life, physical and mental health.
5.Vancomycin and meropenem combined with lumbar cistern drainage and curative effect of psychological intervention on the basis of the analysis of intracranial infection in treatment of brain injury after operation
ling Xiao FANG ; jing Xiao SHEN
Chinese Journal of Biochemical Pharmaceutics 2017;37(10):272-273,275
Objective To explore the basis of intracranial infection after craniocerebral operation with drainage combined with treatment in the application of vancomycin, meropenem and lumbar cistern on the use of psychological intervention clinical value. Methods 55 cases with intracranial infection craniocerebral injury patients were admitted to the Department of neurosurgery in Third Hospital of Jiaxing City in July 2012 to July 2017, the basic treatment in the application of drainage combined with vancomycin, meropenem and lumbar abroad, pay attention to the implementation of psychological nursing. Results The total effective rate of the group was 94.6%. Compared with before treatment, the number of WBC and protein in CSF decreased significantly, and the level of glucose increased significantly, with statistical difference (P<0.05). Compared with the intervention, the psychological status score improved obviously after intervention, with statistical difference (P<0.05). Conclusion The patients with craniocerebral injury complicated with intracranial infection after operation, basic drainage combined with treatment in application of meropenem and vancomycin, lumbar cistern on the use of psychological nursing, can improve the total clinical efficiency, improve psychological status.
6.Effect of psychological intervention and insulin treatment on anxiety in elderly patients with diabetes mellitus
Chinese Journal of Biochemical Pharmaceutics 2017;37(10):270-271
Objective To investigate and analyze the effect of psychological intervention and insulin treatment on anxiety in elderly patients with diabetes mellitus. Methods 92 elderly patients with diabetes mellitus from January 2016 to January 2017 in the first affiliated hospital of Wenzhou medical university chengdu campus were randomly divided into the control group and the experimental group, 46 patients for each group. The control group was treated with conventional insulin therapy, the experimental group was given psychological intervention on the basis of the control group, strengthened communication and exchanges, increased confidence. The anxiety levels of two groups were compared and analyzed. Results After treatment, 46cases were satisfied in the experimental group, and 40 cases were satisfied in the control group. The satisfaction degree of nursing in the control group was 86.96%, significantly lower than 100.00% in the experimental group, which was statistically significance (P<0.05). After the intervention, the HAMA score of the experimental group was (10.54±5.40), significantly lower than (14.63±5.23) of the control group with statistical significance (P<0.05). Conclusion The application of psychological intervention combined with insulin treatment in elderly patients with diabetes could significantly improve the anxiety and the satisfaction of nursing, and has the significance of clinical promotion.
7.Observation on the effect of psychological intervention combined with clopidogrel and Aspirin Enteric-coated Tablets in treatment of non ST segment elevation acute myocardial infarction
Chinese Journal of Biochemical Pharmaceutics 2017;37(10):268-269
Objective To investigate the effect of psychological intervention, Plavix, Aspirin Enteric-coated Tablets combined in the treatment of non ST segment elevation acute myocardial infarction. Methods 102 patients with non ST elevation acute myocardial infarction were selected in Taizhou Central Hospital from January 2015 to January 2017 and divided into study group (n=51) and control group (n=51) by single and double number (hospital admission order) method. The control group were treated with clopidogrel, Aspirin Enteric-coated Tablets, the study group on the basis of routine treatment, were given plavix, Aspirin Enteric-coated Tablets, comprehensive psychological intervention program. Results The total effective rate of the study group was 90.20%, and the total effective rate of the control group was only 70.59%, the difference was statistically significant (P<0.05). Conclusion The application of psychological intervention combined with plavix, Aspirin Enteric-coated Tablets treatment of non ST elevation acute myocardial infarction can significantly improve the clinical efficacy, to ensure the quality of life, life is of positive significance to safety.
8.Hengkangzhengqing combined application of psychological intervention in the bowel preparation before colonoscopy
Chinese Journal of Biochemical Pharmaceutics 2017;37(10):266-267,269
Objective To study the Hengkangzhengqing combined application of psychological intervention in the bowel preparation before colonoscopy. Methods 400 cases of colonoscopy patients from January 2016 to December 2016 were selected and randomly divided into the control group and the experimental group, each with 200 cases. The control group were treated with Hengkangzhengqing, experimental group on the basis of psychological intervention on the mental status of patients and patients, strengthen communication and exchanges, increase the treatment compliance of patients. Comparative analysis of the two groups of patients related clinical indicators. Results In the control group, 100 cases of intestinal cleaning efficacy of 0 scores, and 80 cases of 1 scores. In the experimental group, 80 cases had clean bowel effect, and 70 cases were 1 scores. The intestinal cleaning effect of the experimental group was 90.0%, the percentage of the control group 0~1 scores was 75.0%, and the intestinal cleaning effect of the experimental group was significantly better than that of the control group, with statistical significance (P<0.05) (0-1 scores). The adverse reaction rate in the experimental group was 8.0%, significantly lower than that in the control group (22.0%), with statistical significance (P<0.05). In the control group, 80 cases received excellent bowel preparation, and 70 cases were good. In the experimental group, 110 patients received excellent intestinal preparation and 82 patients were good, the excellent rate of the 2 groups was statistically significant (P<0.05). Conclusion Hengkangzhengqing combined with psychological intervention in a safe colonoscopy application in bowel preparation, can significantly improve the cleaning effect and acceptability, has clinical significance.
9.Clinical study on the perioperative psychological intervention and intraoperative perfusion of total saponins in patients with breast hematoma and skin stasis after operation
Chinese Journal of Biochemical Pharmaceutics 2017;37(10):264-265
Objective To study the clinical treatment effect of intraoperative perfusion of Panax notoginseng saponins on the postoperative mammary gland hematoma and skin ecchymosis. Methods A total of 100 patients who underwent breast minimally invasive surgery from August 2015 to May 2016 in Wenling First People's Hospital were randomly divided into control group and experimental group 50 cases in each group.The control group underwent intraoperative perfusion of Panax notoginseng saponin,on the basis of this, the experimental group were given psychological intervention, pay attention to the psychological state of the patients, strengthen the communication and exchanges with the patients, increased the patient's treatment confidence and treatment compliance. The clinical indicators of the experimental group and the control group were compared. Results After the corresponding treatment, the incidence of postoperative hematoma in the experimental group (4.0%) was significantly lower than in the control group (12.0%), the difference was statistically significant (P<0.05). The probability of skin staining in control group (26.0%) was significantly higher than that in the experimental group (8.0%), the difference was statistically significant (P<0.05). Conclusion Breast minimally invasive biopsy perioperative psychological intervention, intraoperative perfusion of panax notoginseng saponins can reduce the incidence of postoperative mammary gland hematoma, skin ecchymosis.
10.Clinical observation of low dose thyroxine combined with irbesartan and hydrochlorothiazide in the treatment of elderly patients with severe heart failure
ying Xiao YU ; Feng SHEN ; qin Jing HU ; fang Qun LEI ; hong Yan LU
Chinese Journal of Biochemical Pharmaceutics 2017;37(10):262-263,265
Objective To study the clinical efficacy of low dose thyroxine combined with irbesartan hydrochlorothiazide in the treatment of elderly patients with severe heart failure. Methods 60 cases of elderly patients with severe heart failure who were admitted from January 2015 to December 2016 were selected as the research object in this study. They were randomly divided into control group and experimental group, each group was divided into two groups, each with a total of 30 cases. Patients in the control group were treated with conventional therapy, while the experimental group was treated with low dose thyroxine combined with irbesartan and hydrochlorothiazide. Comparative analysis of clinical efficacy of the experimental group and control group. Results After treatment, the total effective number of patients in the experimental group was 26 cases, the effective rate was 86.7%. The total effective number of patients in the control group was 21 cases, the effective rate was 70.0%. Therefore, the effective rate of the experimental group was significantly higher than that of the control group, with statistical difference (P<0.05). After treatment, the experimental group of patients with left ventricular ejection fraction index, four triiodothyronine and three triiodothyronine levels were significantly higher than those before treatment, the control group of patients with left ventricular ejection fraction were significantly higher than before treatment, with statistical difference (P<0.05). Conclusion Low dose thyroxine combined with irbesartan hydrochlorothiazide in the treatment of elderly patients with severe heart failure has better clinical effect, can improve the therapeutic effect in a certain extent, with further clinical promotion and application significance.intervention in two groups. Results The clinical intervention effect of the observation group was better than that of the control group, the stability of the tumor focus, the degree of pain, the quality of life and other aspects were better than the control group, the difference between the two groups was statistically significant (P<0.05). Conclusion Patients with advanced non-smal cell lung cancer chemotherapy choose psychological intervention compound sophora injection combined treatment effect is remarkable, which can effectively improve the patient's clinical symptoms and quality of life.

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