1.Effect of Liuweidihuang Granula Cooperating with Flixotide Aerosol on IFN-? and IL-4 of Asthma Rat Models
Han LIU ; Lining WANG ; Xiaoqi HUANG ; Liying LIANG ;
China Journal of Traditional Chinese Medicine and Pharmacy 2006;0(09):-
Objective: To observe the effect of representative formula of nourishing yin and invigorating the kidney(Liuweidihuang Granula) cooperating with Flixotide aerosol inhalation on the allergic airway inflammation of asthma rat models.Methods: Wistar rats were randomly divided into six groups.Except the norma1 control group,all the other 5 groups were sensitized by injecting into the abdominal cavity of the ovalbumin(OVA) together with aluminum hydroxide as adjuvants,2 weeks later followed by aerosolized OVA challenge to prepare the asthma models.From the eighth day of the experiment,in medication administration teams, rats were sprayed with Flixotide aerosol and given intragastric administration with Liuweidihuang Granula.The normal control group and the asthma model group were drenched with normal saline.Results: There was no difference between the groups given Liuweidihuang Granula and different dosages of Flixotide aerosol but the amount of IFN-? and IFN-?/IL-4 in BALF in the Liuweidihuang Granula cooperating with Flixotide aerosol group were higher than that in the model group(P
2.GC-MS analysis of essential oil from the seeds of Myristica fragrans Houtt in Indonesia
China Journal of Traditional Chinese Medicine and Pharmacy 2006;0(09):-
Objective: To analyze the chemical constituents of the essential oil extracted from the seeds of Myristica fragrans Houtt.(nutmeg) in Indonesia and to provide qualities control scientific foundations.Methods: The essential oil was extracted by steam distillation and separated with GC capillary column.The relative content of every compound was determined by normalization method and the chemical compositions were evaluated by GC-MS.Results: Ninety-three chromatographic peaks were isolated and sixty-one compounds were identified,accounting for 97.62% of the total essential oil in nutmeg.Conclusion: The essential components of nutmeg in Indonesia is monoterpenoids and it's derivatives,accounting for 78.87% of the total essential oil.And phenolic compounds were the secondary composition,accounting for 16.79%.The essential oil contains safrole,which can induce genetoxicity and mutagenicity in animal,and myristicin and elemicin which can induce illusion.So,it must be careful when Myristica fragrans Houtt was used.
3.Effect of Liuwei Dihuang decoction on brain development of intrauterine growth retardation rats
Guang-Xian CAI ; Bai-Yan LIU ; Yi-An CHEN ;
China Journal of Traditional Chinese Medicine and Pharmacy 2006;0(09):-
Objective: To observe the effect of Liuwei Dihuang decoction on brain development of intrauterine growth retardation rats,and to demonstrate the relationship between brain and kidney in TCM.Methods: Animals were divided into 4 groups at random: normal group,model group,Huangqi(HQ) and Liuwei Dihuang(LD) treated groups.The IUGR model was established by passive smoking.On the 19th day of pregnancy,all rats were killed;the total numbers of embryos,the lively,dead and absorbed embryos were counted.The body and brain weight of lively embryos were scaled respectively,then microstructure and apoptosis in brain were observed.Results: Passive smoking can result in the number of dead and absorbed embryos increases.Compared with normal group,the number of apoptotic cells of model group increased.Compared with model group,in Huangqi and Liuwei Dihuang treated groups,the number of dead and absorbed embryos decreased apparently,body and brain weight increased obviously,the number of apoptotic cells reduced significantly(P
4.Effect of basic recipes for removing phlegm and activating blood circulation on index of biochemistry in experimental model of non-alcoholic fatty liver in rats
Jing-Juan HUANG ; Shu-Jun LIU ;
China Journal of Traditional Chinese Medicine and Pharmacy 2006;0(09):-
Objective: Observe the curative effect of basic recipes for removing phlegm and activating blood circulation in experimental model of non-alcoholic fatty liver in rats.Methods: Experimental animal model of non-alcoholic fatty liver in rats were established,then treated with Erchen decoction,TaohongSiwu decoction and the combination decoction.Basic biochemical indexes of rats were tested after treatment.Results: Erchen decoction can reduce the level of liver organ coefficient,cholesterin and aspartate aminotransferase(AST)(P
5.Literature search of TCM syndrome elements of common diseases
Tian-Fang WANG ; Xiu-Yan WU ; Yan ZHAO ; Chun-Guang YU ; Zhi-Geng LI ; Wen-Jie XU ; Cai-Feng DU ; Li LI ; Zhi-Yu WANG ; Qing-Guo WANG
China Journal of Traditional Chinese Medicine and Pharmacy 2006;0(09):-
Objective: To summarize the distributing rule of TCM syndrome elements of common diseases by analyzing the literature of Depression,Chronic Hepatitis B,Chronic Renal Failure,Chronic Obstructive Pulmonary Disease,Menopausal Syndrome.Methods: We selected eligible literatures,then established database with EpiData 3.0 software and computed the frequency of TCM syndrome elements with SPSS 12.0 software.Results: ①Liver,heart,spleen,lung and kidney are common TCM syndrome elements of location of disease.②Yin deficiency,yang deficiency,heat,qi stasis,qi deficiency,blood stasis,damp and phlegm are common TCM syndrome elements of nature of disease.③There are TCM syndrome types between 62 and 148,but the sum of frequency of leading syndrome types which includes disease information is mostly no more than 50%.There are TCM syndrome elements between 19 and 47,but the sum of frequency of leading syndrome elements which includes disease information is mostly above 80%.Conclusion: It is convenient to study TCM syndrome from the aspect of TCM syndrome elements,so we should thoroughly keep on studying TCM syndrome elements.
6.Seven emotions generation and five Zang-organs regulation machanism
Guang-Xin YUE ; Qi-Fu HUANG ; Jia-Xu CHEN ; Chun-Hua JIA ;
China Journal of Traditional Chinese Medicine and Pharmacy 2006;0(09):-
Seven emotions generation relates to the interaction between individual and external objective matters,which is accompanied with interaction between internal desire and external matters.The activity of seven emotions bases on essence of zang-fu organs,being regulated by five zang viscera.Heart is the upstream controller,liver is the key organ to maintain normal emotionds,spleen and stomach is the hub of emotional activities,lung is the auxiliary organ, kidney is origin of emotional generation.Five zang viscera's cooperation and interaction generate the seven emotions.
7.Specialists in the South of the Five Ridges LUO Zhi-yuan Exactly Using Differentiationof Syndrome According to Triple-Jiao to Treat Bubonic Plague
Yong-Chen LI ; Wen LAI ;
China Journal of Traditional Chinese Medicine and Pharmacy 2006;0(09):-
Specialists in the south of the five Ridges LUO Zhi-yuan think that upper-jiao syndrome of bubonic plague appears in the second and third days,middle-jiao syndrome in the period of the third to the sixth days,and lower-jiao syndrome appears at the seventh day.Upper-jiao syndrome of bubonic plague is the most complicated,including the severe syndrome,the critical syndrome,the deadly syndrome.They summarize the six symptoms and signs in middle-jiao of bubonic plague,including "extreme heat and thirst,black and prickly tongue,abdominal distention and pain,stercoroma and delirium,heat accumulation with watery diarrhea,cold feeling of the whole body and hidden pulse",and the four symptoms and signs in middle-jiao,including "pain,distention,stercoroma,heat accumulation with watery diarrhea".They also pointed out that preserving body fluid is key for treating lower-jiao syndrome of bubonic plague.
8.Comments on development of Chinese medical constitution
Qi WANG ; Rui-Lin WANG ; Ying-Shuai LI ;
China Journal of Traditional Chinese Medicine and Pharmacy 2006;0(09):-
Constitution of TCM is based on the study of individual constitution and physical health,and it has also drawn attention from the medical profession in the world.This commentary has reviewed about the development of constitution of TCM over the past few years,summed up the past 30 years,especially analysis the new research fruits during 2005-2006,expounded the important status of Chinese medical constitution in the development of Chinese medicine and the significance in socio-economic sustainable development,and put forward the direction of development and research for Chinese medical constitution.
9.On the relationships between pulse tracing and position,rate,shape and force attributes
China Journal of Traditional Chinese Medicine and Pharmacy 2006;0(09):-
Four key attributes,position,rate,shape and force,are programs of pulse tracing put forward by ZHOU Xue-hai,a medical practitioner in late Qing dynasty.The essences of four key attributes are'images'of di erent levels.There are complex relationships between pulse tracing and position,rate,shape and force attributes,which include not only subordinate relationship and static-dynamic relationship between four attributes but double relationship between four attributes and pulse tracing.
10.Textual Research on Organizational System and Scale of Imperial Drug Institution of Qing Dynasty
China Journal of Traditional Chinese Medicine and Pharmacy 2006;0(09):-
According to the historical records such as The Rules and Regulations in Force of the Ministry of Internal Affairs and raw files of the Ministry of Internal Affairs of the Qing Dynasty(1644-1911) kept in the First Historical Archives of China,a systematic study was made on the establishment,cancel and restoration of the Imperial Drug Institution,the medical organization of the Qing Dynasty after Beijing was established as its capital.A textual research was made into the scale of all the personnel such as officials and bailiffs in the Imperial Drug Institution throughout the Qing Dynasty.All the researches reflect the course of change and development of the imperial medical organizations in the Qing Dynasty.
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