This article presents the discussion on the etiological factors and pathogenesis of chloasma.On the basis of clinical experience and related literature from every dynasty,the author concludes that the causes and pathogenesis of chloasma can be summarized into 8 aspects: 1.Menoxenia,lesion of uterus and cunnus,tumors in pelvic cavity in women;excessive heat and deficiency of kidney essence in men.2.Damages in Chong-Ren meridians,e.g.infection of pathogen which goes directly into Chong-Ren;exhaustion of essence blood;coldness,phlegm or blood clot congests within the Chong-ren meridians.3.Stasis of liver-qi induced by insufficiency of blood storage and dysfunction in conveyance and dispersion.4.Shortage of essence blood.5.Lack of kidney-yang.6.Disharmony between spleen and stomach,including deficiency of spleen-stomach qi,spleen-stomach yang,and stomach yin,and surplus of stomach heat.7.Flooding of turbidness and heat,like moisture and heat in liver-gallbladder and in spleen-stomach.8.Invaded by exogenous pathogen of wind and sunlight.Knowing these points has great significance on directing therapy according to syndrome differentiation.

This article introduces the academic thoughts and clinical experience of LIANG Shi-shao,a late famous TCM practitioner in Guangxi.Professor LIANG had practiced medicine more than 60 years,having rigid attitude toward teaching and great scholastic achievement,being good at treating diseases caused by exogenous pathogenic factor and internal damage,specializing in senile diseases.He thought highly of vital qi in clinical treatment,applying invigoration method in flexible way to preserve gastric qi.Because dwelled in south of china,professor LIANG was also skilled in treating warm disease,having original experience and comprehension of applying "clearing,hua,purgative" to remove dampness.In clinical practice,he was also good at improving drugs and prescription in order to curing difficult and complicated diseases,formatting a unique style of principle of diagnosis and treatment and experience.

Some medical charicteritics in the early ancient times are discussed centering on Yijingbianqi Lun in Suwen in order to expound the far-reaching impact of introspection-characterized Chinese culture on early traditional Chinese medicine.At the same time,the article also discussed Stability and Wisdom in the embodiment of Inner Canon of Huangdi.

The corresponding season of the ve zang-viscera is the important content of the correspondence between man and universe theory in the Inner Canon of Huangdi,and the corresponding season of the ve zang-viscera related to several modes of calendar.With the exception of the way that combine the ve zang-viscera with calendar which make use of criss and cross or divide into ve parts on 12 months of a year,the authors believe that the newly discovered ancient ten months' calendar had been showed clearly in the Inner Canon of Huangdi.The text of the Inner Canon of Huangdi that cannot be explained well in accordance with twelve months' calendar can be explained by ancient ten months' calendar,and the ancient ten months' calendar is the basis that the ve phases theory is derived from the concept of the ve seasons.

According to the historical records such as The Rules and Regulations in Force of the Ministry of Internal Affairs and raw files of the Ministry of Internal Affairs of the Qing Dynasty(1644-1911) kept in the First Historical Archives of China,a systematic study was made on the establishment,cancel and restoration of the Imperial Drug Institution,the medical organization of the Qing Dynasty after Beijing was established as its capital.A textual research was made into the scale of all the personnel such as officials and bailiffs in the Imperial Drug Institution throughout the Qing Dynasty.All the researches reflect the course of change and development of the imperial medical organizations in the Qing Dynasty.

Though the clinical observation of 413 cases of epidemic hemorrhagic fever(EHF) by clinical epidemiological method,we have concluded that the main TCM etiological factors of EHF are damp,toxic heat,blood stasis and deficiency, and the determinant pathogenesis of EHF is the integration of interior and exterior pathogenic factors;the syndrome characteristic of EHF is that the cold,heat,deficiency and excess were intermingled,and the moist heat blood stasis syndrome should be given priority to;its major pathological location is initial YANG and triple warmer;so the therapeutic principle should be the integration of cold-warm syndrome and exterior and interior and paying attention to smoothing the triple warmer all the time.

This article respectively introduces famous doctor ZHANG Xi-chun’s original experience of using mineral drugs from four parts: taking suitable measures in accordance with the disease mechanism,syndrome,herbs,clinical experience,which hope to inspire and guide our clinical doctors.

Objective: To evaluate effect of combination of PA and RES on human gastric carcinoma cell MGC803 in vitro.Methods :The effects of PA and RES were measured by MTT assay.Morphous of cell was observed by light microscope.Flow cytometry was used for MGC803 cell cycle analysis.Results: PA significantly inhibited the growth of MGC803 cell in a dose and time dependent way(P

"Absorbing image "is an important method in establishing fundamental theoretical system of TCM.The term and concept of "nomenclature according to manifestations" is the starting point of theoretical thoughts and the results of scientific studies."Testing viscera via the state of internal organs" is a method of "understanding the interior from the exterior",which makes TCM surpass productivity level and practical tools of that time,finally aquire knowledge.The huge theoretical system of TCM is constructed on the basis of "classification according to manifestation",discovering unknown fields according to infinite knowledge.

Objective: To observe effect of Kechuanning on expression of nuclear factor kB(NF-?B) in lung tissue of bronchial asthmatic rats.Methods: 40 rats were randomly divided into 5 groups: the normal group,the model group,Kechuanning high-dose group(27g/kg),Kechuanning low-dose group(13.5g/kg),GuilongKechuanning control group(0.45g/kg),8 rats in each group.The bronchial asthmatic model was established by egg protein sensibilization and long-term inhalation provocation.The rats of each treatment groups were lavage administration each day from the first time of provocation to execution.After 4 weeks of treatment,the rats were killed and lung tissue were taken to dyeing of HE to be observed.The expression of NF-?B in lung tissue were determined by immunohistochemistry.Result: Compared with the normal group,the thickness of bronchus wall and bronchus smooth muscle,the numbers of eosinophile granulocyte and leukomonocyte,and expression of NF-?B in lung tissue were increased in the model group(P