Objective: To study the antiviral effect of polysaccharides from brown seaweed Lobophora variegata. Method: The crude polysaccharide was extracted with boiling water and precipitated with ethanol,and then fractionated with ion exchange chromatography. Its antiviral activity was tested by cytopathic effect (CPE) reduction assay and plaque reduction assay. The cytotoxicity of the water crude extract was determined by MTT method. Results: The crude water extract showed markedly antiviral activity against herpes simplex virus (HSV) type 1 and type 2 including ACV resistant strain and clinical strains with low EC50 values of 18.2 and 6.25 μg/ml respectively. It also showed very low cytotoxicity to Vero, HEp-2 and MDCK cells. Therefore, the crude extract possessed high selective index for antiviral effect. It also had some inhibitory effect on respiratory syncytial virus (RSV) but had no effect on influenza A virus. Two fractions were isolated from the water crude extract and they exhibited anti-HSV activity in the test of CPE reduction assay in Vero cells. Conclusion: Seaweed Lobophora variegata contains antiviral polysaccharides with high inhibitory effect on herpes simplex virus.

Iron deficiency (ID) and iron deficiency anemia (IDA) remain prevalent nutritional problems in many parts of the world. Among infants and young children, IDA has adverse effects on growth and development. Mental deficits exhibited in infancy can be long lasting. Efforts are being made to combat these problems. However, in the past decade little success was made. Currently there is interest in developing home fortificants that are versatile, inexpensive, efficacious and effective. One of these is the Sprinkles, which contain iron fumarate coated with a soy lipid and other micronutrients. The Sprinkles is packaged in small sachets and intended to be added to ready-to-eat home-prepared complementary foods once a day. An acceptance test was conducted in 5 cities in China. The Sprinkles was provided for the acceptance by infants aged 6-24 months and children of 2-5 years in 4 successive weeks. Their mothers were interviewed 4 times during the period of the study. The results showed that both the mothers, the infants and young children accepted the foods with added Sprinkles well.

Objective: To study the health effects of selenium tea on cardiovascular system. Methods : Four groups of Wistar rats were fed standard diet and water, standard diet and selenium tea , high fat diet and water ,high fat diet and selenium tea respectively. Twelve weeks later, the plasma apoA , apoB, body weight, whole blood viscosity , plasma viscosity , and hematorcrit were determined while plasma fibrinogen and inhibition of erythrocyte aggregation were calculated. Results: At the end of the experiment ,the plasma apoA level of selenium tea groups was significantly higher than that of control group, while the ratio of apoB/apoA was significantly lower than that of control group. Selenium tea decreased the whole blood viscosity, plasma viscosity and inhibited erythrocyte aggregation and body weight. Conclusion: Selenium tea could significantly improve the lipoprotein metabolism and hermorrheology and decrease body weight of the rats fed high fat diet.

950 mg/d) group was significantly higher than those in median or low calcium intake group,among girls with BB genotype. However,such significant effect was not detected among girls with b allele. Conclusion:The PTH BstBⅠ polymorphism has significant interaction effect with calcium intake on bone mass accretion in Chinese adolescent girls. High calcium intake would be beneficial to gain higher bone mass accretion for girls with BB genotype than those with b allele.

Objective: Lumiflavin fluorescence method was developed to detect the content of riboflavin in urine. Metheds: Based on decomposition of riboflavin into lumiflavin, fluorescence method was used to determine riboflavin in urine. Results and conclusion: This method was simple, fast, accurate and the relative SD was from 1.11% to 9.51%, and the recovery was from 92.8% to 100%.