Objective To investigate the clinical efficacy of cobamamide combined with Longxuejie in the treatment of herpes zoster in the elderly .Methods 104 elderly patients with herpes zoster were randomly divided into the treatment group and the control group .Both the two groups were given orally famciclovir 250mg,3 times a day for 14 days,intramuscularly injected gland glycosides cobalamin 500mg,1 day,14 days a course of treatment ,the treat-ment group was given Longxuejie enteric-coated tablets 4,3 times a day orally for 14 days.The blisters disappeared , pain relief,and recovery time of completely crusted ,treatment efficacy and neuralgia were compared between the two groups.Results In the treatment group,34 cases were cured,effective in 13 cases,total effective rate was 90.4%, which was significantly higher than 73.1% in the control group,the difference was statistically significant (χ2 =5.216,P<0.05).The blisters disappeared,pain relief,and recovery time of completely crusted in the treatment group were significantly shorter than those in the control group (t =3.216,5.432,4.643,3.654,all P <0.05).No postherpetic neuralgia was observed in the treatment group ,the incidence rate of postherpetic neuralgia of the control group was 13.5%,the difference was statistically significant (χ2 =4.875,P<0.05).Conclusion The Longxuejie combined with cobamamide in the treatment of herpes zoster in elderly patients has reliable effect ,fast improvement of clinical symptoms,a low incidence of postherpetic neuralgia ,it is worthy of clinical application .

10 kinds of normal and immunodifi-cient mice were used and they were found to have different levels ofNK activity.The NK activity toHuman to Human,Human to Mouseand Mouse to Mouse hybridomacells was much lower thanthat to YAC-1 cells in all mice andthere were no significant differencesbetween the two kinds of human Bcell hybridomas in susceptibility toNK cells.The results showed thatNK cells had no obvious effects onxenografts of human B cell hybri-domas.

The red blood cell sorbitol levels of 23 healthy subjects and 66 diabetic patients were measured enzymatically. Results showed that erythrocyte sorbitol levels of both IDDM (17) and NIDDM (38) patients with poor control were significantly higher than that of the controls and positively correlated with the coincident plasma glucose concentration, 24-hour urinary glucose excretion and HbA1c. There was no significant difference between the red cell sorbitol concentration of NIDDM with normal blood glucose level and that of the normal group; moreover, red cell sorbitol levels did not sig-nificantly correlated with FBG in both groups. Although there was no significant difference between the FBG of poorly controlled IDDM and NIDDM groups, red blood cell sorbitol levels were significantly different in both groups. This suggested that red blood cell sorbitol level could be used as an indicator of diabetic control.

The present paper is an analysis of the pattern reversal visual evoked potentials (P-VEP) of macular disease (40 cases, 57 eyes), in contrast to normal persons (40 cases, 80 eyes) of similar age. The group consists of 9 different kinds of disease-central serous chorioretinopathy macular hemorrhage, macular dege-neration, etc. The authors analyzed the latency and amplitude of P-VEP in different macular disease with different course and central vision. The results showed that the latency of P-VEP in the group was relatively prolonged. In contrast to normal person P 100 was prolonged by 9.0, 26, 40 ms at 1?2′, 30′, 16′ visual angles respectively. The amplitude was obviously lowered, especially at the visual angle of 16′ and P-VEP extinguished in all the eases with visual acuity less than 0.1.The latency and the amp-litude were not related to the type and the course of the maeular disease, but were closely related to the central vision.

OBJECTIVE:To enhancement lawconsciousness and ability of self-protect of pharmacist.METHODS:Analysed the problem which occured in their work from the point of view of law and bring forward some advice.RESULTS &CONCLUSION:Pharmacist should do their work strictly according to the code for avoidance law risk.

OBJECTIVE: To enhance the quality of pharmaceutical care of licensed pharmacists in medical services, and to ensure safe, effective, economical, and rational use of drugs. METHODS: The status quo and the problems existing in the legal guarantee of licensed pharmacists in medical service were analyzed, and the necessity of reinforcing legal guarantee for licensed pharmacists in medical service and the feasible measures were discussed. RESULTS & CONCLUSIONS: It is urgent to set and enforce "Licensed Pharmacist Law" to safeguard the legal rights of licensed pharmacists in medical service in the mo-de of law, facilitate the implementation of licensed pharmacist system in medical service, consummate management on licensed pharmacists, reinforce licensed pharmacists' consciousness of legal guarantee, and enhance the quality of pharmaceutical care.

Objective To explore the expressions and significances of sICAM-1 and sCD44v6 in peritoneal lavage fluid after laparoscopically assisted radical gastrectomy,in order to evaluate the risk of laparoscopically assisted radical gastrectomy for the peritoneal plant transfer.Methods Ninety-two patients with gastric cancer were randomly divided into the control group and the experimental group.The control group was treated with open laparotomy and the experimental group was treated with laparoscopic surgery.The concentrations of both sICAM-1 and sCD44v6 were detected by enzyme linked immunosorbent assay.The positive rates of tumor cells in the two groups were compared.Results The expressions of sICAM-1,sCD44v6 in the two groups before operation had no significant difference (t =0.198,P =0.543 ; t =0.897,P =0.429).After operation,sICAM-1 and sCD44v6 levels increased significantly,but there was no significant difference between the two groups (t =0.766,P =0.312 ; t =1.092,P =0.129).The positive rates of tumor cells in the two groups before and after operation have no significant differences (x2 =0.789,P =0.287 ; x2 =0.912,P =0.198).Conclusion Laparoscopically assisted radical gastrectomy does not increase the expression of sICAM-1 and sCD44v6 in peritoneal lavage fluid and the risk of peritoneal metastasis.It is worthy of clinical poptdarization and application.

Objective:To summarize the anesthesia experience of open heart surgery in 43 infants(weigh less than 5kg) and to explore the related issues with myocardioprotection and brain protection.Methods:Conventional induction of anesthesia,nasotracheal intubation,arteriovenous puncture,cardiopulmonary bypass were established,according to the needs for maintaining the body low temperature(deep,middle,superficial);haemodynamics was maintained with vasoactive agent after aorta was opened.Results:Two infants with transposition of conducting arteries succumbed to stoma leak.One infant with tetralogy of Fallot succumbed to low cardiac output syndrome,bellows complication appeared in 8 cases,Ⅲ.atrial ventricular block 1,and the rest infants recovered well.Mortality was 6.98%in this group.Conclusion:Cardiac anesthesia control in infants with low weight is difficult,death rate is hiqh and complication is complex.Butas long as control is done well,mortality omd complitation can be devreased.

Objective:To study the status quo of quality of life and its influencing factors among Junior High School Students of Three-Gorges Reservoir and Non-Three-Gorges Reservoir in Chongqing,and to provide basis for students' QOL improvement.Methods:672 Three-Gorges Reservoir students and 630 Non-Three-Gorges Reservoir students were tested by using the Quality of Life Scale for Junior High School Students(JHSS-QOLS).Multiple stepwise regression analysis was utilized to study the major factors affecting QOL of students in Chongqing.Results:The quality of life of junior high school students in Three-Gorges Reservoir was higher than that of students in Non-Three-Gorges Reservoir.Physical exercises,sleep,chronic disease,parental rearing style were important influencing factors in quality of life of students.Conclusions:The key steps of improving the quality of life of Junior High School Students should include reducing the learning load of students,the prevention and control of chronic disease and the improvement of parental educational level.

Objective:To study the clinical value of susceptibility weighted imaging(SWI)in brain diseases.Methods:37 cases with blood vessel pathological change of brain diseases were collected and analyzed,including 8 example of angioma cavernosum,10 cerebral infarction,15 brain tumor,2 venous malformation and 2 venous sinus thrombus.Conventional T1WI,T2WI,DWI,the SWI and enhanced T1WI,MRA images were performed to compare the superiority of the SWI images to the others in demonstrating the small hemorrhagic focuses,the small vein,hemosiderin,calcification and other paramagnetic materials.Results:SWI could distinguish the hemorrhage from the blood vessel and discover the smaller hemorrhagic focuses of the angioma cavernosum.It could discover more tiny veins adjacent to the dilated draining vein.SWI could detect small hemorrhages in acute cerebral infarction and small draining veins in brain tumor.And draining veins in deep part and expanded rete venosum in the surfaces of brains could be obviously demonstrated when sinus venosus thrombus occurred.Conclusion:SWI is a new pulse sequence that can demonstrate the abnormal low current capacity blood vessels,the structure of small vein,the tiny hemorrhages as well as ferrugination and calcium deposition sensitively.So it can be applied in the diagnosis and antidiastole of the central nervous system diseases as an important supplement to the MRI conventional sequences.