One hundred mandibles of adult Chinese male unearthed in Shanghai without missing teeth, alveolar bone resorption or/and malposition of teeth were studied. Our data showed that the location of the mental foramen below the apex of the lower second premolar was the most common. Our results were compared with those of other investigators. The Clinical significance of iden.tifying the anatomical location of the mental foramen in dental practice is discussed

Renal fibrosis is the final common pathway to all progressive renal disease.Studies have found that Wnt pathway exists in the process of renal fibrosis and plays an important role in the process of renal fibrosis.This paper reviewes the relation of wnt pathway and renal fibrosis.

BACKGROUND: Mental health is the most important internal resource that individual can depend on and also an important factor which affects the existence and development of individual. But there are few studies on the level and characteristics of mental health of female prisoners during serving a sentence.OBJECTIVE: To investigate the level and characteristics of mental health of the female prisoners in Shandong Province.DESIGN: Retrospective, cross sectional,multi-variable and sampling survey based on female prisoners.SETTING: Department of Technology in Shandong Police College.PARTICIPANTS: The investigation was completed in the Shandong Police College frotm January 2002 to March 2002.Totally 393 female prisoners from the Shandong Female Prison were selected with the grouping-sampling method to give the questionnaire and attend the investigation voluntarily,and the persons with definite mental disease were excluded.METHODS: The mental health items of female prisoners,including 9 factors such as somatization, obsessive-compulsion,sensitivity of human relations, depression, anxiety, hostility, phobia anxiety, paranoid ideation and psychosis,were explored with Symptom Checklist 90(SCL-90), and the judging standard of psychologic obstacle was whether the total scores of positive symptoms were 2 standard deviations more than those of the norm or not.And combined with the archives of the female prisoners and the questionnaire of self-editing item,relative data were collected. The uniform instructional words and the methods of filling in were explained to the female prisoners firstly,and then the answers of the questionnaire were written collectively.MAIN OUTCOME MEASURES: The mental health level and the psychological characteristics of female prisoners.RESULTS: 393 questionnaires were provided.There were 15 questionnaires excluded because more than 5 questions were missed in the paper or responsion consistency deviation appeared obviously after callback.378questionnaires were valid ,and the effective rate was 96.2%. ①The item numbers of positive reaction,total average score,toatal average score of positive symptoms of SCL of the prisoners were higher respectively than those of the norm of general group and reached the most significant level.The psychological problems of different degrees were widespread among them.②There were 372 female prisoners who had positive symptoms, and the detection rate was 98.41% ,which was more than that of positive symptoms in prisoners (40.6%).The significance of difference existed(x2=503.59,P ＜ 0.001).There were 84 persons who had psychologic obstacle in the female prisoners,and the detection rate was 22.2%,which was higher than that of in the general group (10.54%).The significance of difference existed (x2=54.128,P ＜ 0.001). ③The scores of 9 factors of SCL were all higher in the female prisoners than in the adult norm of the country,and reached the most significant degree. It showed that the obvious abnormality existed in the somatization, obsessive-compulsion, sensitivity of human relations, depression, anxiety, hostility, phobia anxiety,paranoid ideation and psychosis of the tested persons, and the ordering of them was sensitivity of human relations ＞hostility ＞obsessive obsessivecompulsion ＞depression ＞somatization ＞anxiety ＞phobia anxiety/paranoid ideation＞psychosis. Among the 9 factors,the average scores of obsessivecompulsion, sensitivity of human relations, depression,and hostility were greater than 2,and the symptomatic reaction of them was already above moderate. ④The detection rates of psychological problem or psychologic obstacle of the factors such as paranoid ideation, hostility, somatization,sensitivity of human relations and anxiety,etc.were higher,which indicated that these were the main psychological deviation contents.CONCLUNSION: Compared with the general group,the total level of mental health of female prisoners is lower, and the detection rate of psychologic obstacle and the degree of symptomatic reaction are obviously higher,and the psychological characteristics such as phobia anxiety, obsessive-compulsion,sensitive-suspiciousness, depression and hostility,etc are outstanding.

BACKGROUND: Every year there are case reports about freshmen who took extreme actions because of maladaptation. Freshmen's mental health is related not only to their adaptability to university life but also to the stability and harmony of university campus.OBJECTIVE: To investigate the level of freshmen's mental health in early university life and screen out the students with severe psychological problems.DESIGN: A cross-sectional study.SETTING: Department of Education, Shaoxing University of Zhejiang Province.PARTICIPANTS: A total of 4 417 freshmen of year 2003 from Shaoxing University were selected as observational subjects during November 2003.METHODS: The status of mental health was surveyed with symptom checklist-90 (SCL-90), self-rated anxiety scale (SAS), and self-rated depression scale (SDS). SCL-90 consisted of 9 dimensions: somatization, obsessive-compulsive, interpersonal sensitivity, depression, anxiety, hostility,phobic anxiety, paranoid ideation and psychoticism, and 5 evaluation scales: 1 as none, 2 as mild, 3 as moderate, 4 as severe and 5 as rather severe. The higher the score, the lower the level of psychological health was. They were evaluated as whether they had problem of psychological health or not. SAS contained 4 grades that recorded mainly the frequency of the appearing symptoms defined by the evaluation entry. The standard score took 50 points as the critical point. The higher the score, the more severe anxiety status was. The main statistical index of SDS was the exponent of depression severity that ranged from 0.25 to 1.00. Those with less than 0.05 had no depression, 0.50-0.59 mild depression, 0.60-0.69moderate depression, and above 0.70 severe depression. The group test was conducted among the freshmen 3 months after they entered the university.MAIN OUTCOME MEASURES: The scores of SCL-90, SAS and SDS.RESULTS: A total of 4 417 questionnaires were sent out, and 4 387questionnaires were collected with the effective rate of 99.32%. ① The scores on obsessive-compulsive, phobic anxiety and psychoticism ih the freshmen were higher than those of the norms (t=2.88-4.82, P ＜ 0.01). Among them, 333 freshmen with common psychological problems were detected, which constituted 7.59%. Another 49 students with severe psychological problems were screened out, which made up 1.12%. ② There were significant sex differences of scores in SCL-90 factors between boys and girls (total average t=5.56, P ＜ 0.01). ③ There was a significant correlation of depression and anxiety of SCL-90 scores with the standard scores of SDS and SAS, respectively, and the coefficient of product-moment correlation was 0.532 and 0.361, respectively.CONCLUSION: ① The freshmen did not have good psychological health.② The girls had more psychological problems than the boys. ③ The scores on depression and anxiety of SCL-90 were mutual proof with the standard scores of SDS and SAS, respectively.

Biochemistry is one of the important basic courses.There are some exploration and thinking on biochemistry teaching reform from teaching features of medical education,the application of teaching basic principles and the designing of teaching regulation forms.

Objective To investigate the human papillomavirus (HPV)E6/E7 mRNA detection used in cervical cancer screen-ing.Methods In the study,160 patients treated in gynaecology department of the hospital were enrolled,whose samples were col-lected for ultra-thin liquid-based cytology(thin prep cytology test,TCT).According to the TCT results,the patients were divided into 4 groups,including normal group(n=32),CINⅠ group(n=44),CINⅡ group(n=67),CINⅢ group(n=17).In addition to the CIN classification,according to the type of pathology the patients′groups were also devided.In different groups,the differences be-tween HPV E6/E7 mRNA and HPV DNA positive rate were compared respectively.The differences between HPV E6/E7 mRNA and HPV DNA levels among different pathology groups were also compared.Results In groups of different CIN grades and control group,the positive rate of HPV E6/E7 mRNA and HPV DNA test showed statistically diffrences (P <0.05 ).Compared among different pathologic groups HPV E6/E7 mRNA and HPV DNA levels were statistically significant (P <0.05).Conclusion In cer-vical cancer screening,HPV E6/E7 mRNA screening can be used as a screening method and its combined use with cytological meth-od would be helpful to improve the diagnostic accuracy.

Objective To study the effect of biofeedback electrical stimulation combined with pelvic floor muscle training in the postpartum rehabilitation treatment of pelvic floor function.Methods 320 puerperants who were rechecked at 42d after the delivery in our hospital from September 2011 to January 2013 were divided into two groups,patients in the observation group were treated with biofeedback electrical stimulation combined with pelvic floor muscle training ,patients in the control group were given without treatment intervention,then the pelvic floor muscle tension,vaginal muscle voltage and urinary incontinence rate of two groups at 3 month after the treatment were compared.Results The improvement of pelvic floor muscle tension and vaginal muscle voltage of observation group were significantly better than those of control group (<0.05),the urinary incontinence rate was significantly lower (<0.05) .Conclusion The biofeedback electrical stimulation combined with pelvic floor muscle training can effectively improve the pelvic floor muscle tension and decrease the urinary incontinence rate,so it can improve the life quality of puerperants.

Objective To observe brain-protection effect of Jiannao Yizhi Capsule on ischemic stroke and explore its mechanism. Methods One hundred and eighty cases of ischemic stroke patients were divided into two groups. Sixty cases in control group were treated with conventional method, one hundred and twenty cases in treatment group were treated with Jiannao Yizhi Capsule on the basis of conventional method. Levels of endothelin (ET), calcitonin gene related-pepitide (CGRP), lipin peroxidation oxidase (LPO) and super oxidase dismutase (SOD) of the two groups were determined. Results There were significant differences in reducing levels of ET and LPO, enhancing levels of CGRP and SOD, improving neurological impairment, reducing levels of blood lipid and blood viscosity between the two groups (P

We tried to clarify the role of oxygen radicals [released from granulocytes stimulated by phorbol myristate acetate (PMA) in rat acute lung injury. It was found that DNA strand-break damage (DSBD) in peripheral white blood cells was significantly increased 40 min after injection of PMA. DSBD in lung tissue of rats treated with PMA was also markedly increased. The PMA-treated rats showed significantly higher lipid-peroxide (LPO) level in plasma and lung hemogenate than the controls. These results suggest that determination of DSBD, a simple and sensitive indicator for oxygen radical damaging, might be useful in the diagnosis of adult respiratory distress syndrome, when it is used together with measurement of plasma LPO.

Objective:To study the effect of adriamycin(ADR) as therapeutic agent inducing rabbit posterior capsular lens epithelial cell apoptosis and to assess the relationships between P53,Bcl-2 after lens extracapsular extraction.Methods:Twelve rabbit eyes were injected with 0.2mg ADR(0.4mg?L -1 ) during lens extracapsular extraction performed respectively in the third week and the eighth week after the operation.With TdT-mediated dUTP nick end labeling(TUNEL)and immunohistochemical(SABC) staining.The protein expression cell rate of P53 and Bcl-2 were detected.Results:Positive pericyte muclei labeled by TUNEL increased more significantly than those in the control guoup from the third week to the eighth week after the operation.P53 protein expression was significantly higher(P