Acute cerebral infarction needs a fast and effective imaging examination to help determine the diagnosis,analyze the causes,guide the treatment,and determine the prognosis.Multimodal CT examination obtains a wide range of reformation in a single scan,including anatomy,hemodynamics and etiology,and provides objective imaging evidence for comprehensive evaluation and appropriate treatment of cerebral infarction.This article reviews the application of this technology in acute cerebral infarction.

Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Common Cold ; prevention & control ; Female ; Humans ; Male ; Medicine, Chinese Traditional ; Middle Aged

Congenital heart disease and airway anomalies are correlated,and some special cardiovascular anomalies accompanying with airway anomalies like vascular tings,have a high morbidity.Congenital heart disease with airway anomalies is usually ignored in clinic.It should be considered that congenital heart disease with airway anomalies exists in children with the symptoms,such as repeated stridor,respiratory failure,difficult intubation or failure of postoperative ventilator weaning.Multidetector helical CT and bronchoscopy are important for making early diagnosis and guiding management for congenital heart disease with airway anomalies.The choice of therapeutic approaches depends on the type of airway anomalies,location and degree of the lesion.

OBJECTIVE: To establish the quality standard of Guanxinjing capsule. METHODS:Ligusticum chuanxiong, Borneolum Syntheticum, Radix Paeoniae Rubra, Panax ginseng and Panax notogiseng were identified qualititively by TLC. The content of Protocatechuic aldehyde in salvia miltiorrhiza was determined by HPLC. RESULTS: The TLC spots were distinct and well-separated. The average recovery of the added sample was 99.91% and RSD was 1.56%. CONCLUSION: The established standard is suitable for the quality control of Guanxinjing capsule.

OBJECTIVE:To optimize the coating technology of modified release film of budesonide colonic localization tablet. METHODS: The effect of the coating parameters such as spray gun position, spraying rate, spraying atomization pressure, intake air temperature and flow, temperature of tablet bed on the microporous semipermeable film and the enteric film of localization tablet were investigated, respectively. RESULTS: The distance between spray gun muzzle and tablet bed was established as 10～20 cm; the spraying rates of the microporous semipermeable film and the enteric film of localization tablet were 3 and 1 mL?min-1, respectively, with their spraying atomization pressure at 2 and 1.5 bar(1 bar=105 Pa), intake air temperature at 50～55 ℃ and 40～45 ℃, temperature of tablet bed at (40?1) ℃ and (30?1) ℃, flow rate of intake air at 5 and 7 m3?min-1 respectively. The weight of the optimized localization tablet after being coated with semipermeable film and enteric film increased by 10% and 5%, respectively. The cumulative drug release within 24 h reached (77.5?8.6)% and the lag time was (6.0?0.5) h. CONCLUSIONS: The optimized coating technology is suitable for the preparation of modified film of budesonide colonic localization tablet.

Arytenoid Cartilage ; injuries ; Humans ; Joint Dislocations ; surgery ; Laryngoscopy ; methods

PBL and CTM integration method is a kind of heuristic education mode of regarding student as the center of education.In order to explore the application result of this teaching method in the curriculum of nursing ethics laws and regulations,we put this mode into practice and regard nursing students as research objects.Questionnaire investigation and paper test are applied to evaluate the teaching effect.The study result shows that PBL and CTM integration method is certainly a well-established method to enhance teaching quality in the curriculum of nursing ethics laws and regulations.

Objective To analyze clinical features of papillary thyroid microcarcinoma(PTMC) and to evaluate the diagnosis and treatment for PTMC.Methods The clinical data of 447 cases of PTMC receiving surgical treatment and confirmed by pathology were reviewed.Color Doppler ultrasonography was used to identify thyroid nodules and cervical lymph nodes,and frozen section was used to confirm the pathological diagnosis during operation.104 cases received unilateral lobectomy,22 cases received unilateral lobectomy plus isthmectomy,321 cases received total thyroidectomy,257 cases underwent central neck dissection,and 54 cases underwent lateral neck dissection(level Ⅵ included).All cases took levothyroxine to maintain low TSH level after operation,and were followed up through telephone or in out-patient clinic.Results Central compartment node metastasis was found in 144 patients,and lateral neck metastasis was found in 41 cN1 cases.The age,extra-capsular invasion and multifocal carcinoma were independent risk factors of PTMC.The number of positive nodes in level Ⅵ was positively correlated with the risk of lateral node metastasis.395 cases were followed-up successfully for 20 to 42 months,with the media follow-up of 32 months.During the follow-up,recurrence or metastasis was found in 15 cases,and no death happened.Conclusions PTMC has no specific symptoms,and was difficult to be diagnosed before operation.Physical examination and color Doppler ultrasonography should be used as routine examination.Thyroid lobectomy and total thyroidectomy plus central node dissection should be major surgical treatment for PTMC patients.Lateral neck dissection should be considered in all cN1 patients.

A systematic review is based on randomized controlled trials (RCTs), and the reliability of its conclusion is closely related to the quality of original literature. The low quality of existing RCTs in China leads to the failure of conclusive findings in systematic reviews when evaluating the effectiveness of interventions. It is almost universal for systematic reviews to draw the conclusion that "further well-designed multicenter and large-scale RCTs are still required to confirm the beneficial effects of interventions". This paper analyzed the current status of RCTs in China, discussed the influence of including trials of low quality in a systematic review and assessed how a systematic review should be carried out under such circumstances. Furthermore, the methods to evaluate the quality of RCTs were introduced and evaluated. Finally, several strategies were proposed to improve the quality of RCTs in China: foster an honest academic and social environment, enhance the training of doctors on clinical research methodology, promote the implementation of clinical registration systems and strengthen the quality control of clinical research and the medical journals regulations on the quality of submitted papers.

Objective To investigate the methods for the detection of serum samples with low-concentration HBsAg and its clin-ical value.Methods Serum samples with HBsAg weak positive were measured by ELISA or using Roch cobas e601 were collected from the clinical laboratory.The samples with low-concentration HBsAg were confirmed by neutralization assay by using Lizhu ELISA reagent Kit or Roch cobas e601 analyzer.at the same time,ALT/AST concentrations and HBV DNA copies were also deter-mined.Results Among 53 samples that showed weak positive reaction by using Kehua reagent kit,37 samples were positive in neu-tralization test,while the other 16 samples were negative.Among 18 samples that showed weak positive reaction tested by using Roch cobas e601 analyzer,13 samples showed positive in neutralization test,and the other 5 samples showed negative.Conclusion The results of HBsAg test varies in different detection System.The clinical significance of samples with low-concentration HBsAg needs further study.