Costs And Cost Analysis ; Delivery Of Health Care

BACKGROUND AND OBJECTIVE

The burden of treatment delay in breast cancer is high, especially among developing countries. Despite adversely affecting morbidity and mortality, treatment delay remains unexplored in the Philippines. This study aimed to determine treatment delays among breast cancer patients in a tertiary hospital during surgery, neoadjuvant chemotherapy, and adjuvant chemotherapy, and to identify predictors of delay.

A cross-sectional study was conducted among breast cancer patients seen between January 1, 2012 to December 31, 2018. The following outcomes were investigated: ≥90 days from initial diagnosis to surgery, ≥8 weeks from diagnosis to initiation of neoadjuvant chemotherapy, and >120 days from diagnosis to initiation of adjuvant chemotherapy. Summary statistics were reported as percent for categorical data and as mean for continuous data. The individual correlations were performed using Chi-square for qualitative data and t-test for quantitative data while predictors were determined through logistic regression.

A total of 324 patients were included in this study. The majority of the patients were less than 65 years old living in urban areas. More than half of the patients were overweight or obese, hypertensive, and diabetic. The following delays were observed: 61.1% (n = 198) with any type of delay, 23.8% (n = 53) with delay in surgery, 53.8% (n = 120) with delay in adjuvant chemotherapy, and 74.3% (n = 75) with delay in neoadjuvant chemotherapy. The patients noted to have any type of delay were more likely to be hypertensive (p = 0.046) and residing in urban areas (p = 0.041). There were no differences in the distribution of age, body mass index, and presence of co-morbid conditions such as hypertension, diabetes mellitus, coronary artery disease, and heart failure among those with any form of delay compared with no delay.

The present study shows the presence of treatment delay among breast cancer patients and may be used to enact policy changes to optimize breast cancer care delivery. Further studies may be done to identify other factors affecting these delays and policy changes are recommended to address these gaps in surgery and chemotherapy administration among breast cancer patients.

BACKGROUND AND OBJECTIVE

Given the rigors of medical training with its high documented prevalence of mental issues as well as the global need to safeguard the well-being of medical students, there is an urgency to assess the well-being of medical students and their perception of support from their respective medical schools during their education. This also applies in the context of public medical school students in the Philippines, where there is still a relative lack of literature. This cross-sectional study investigates the well-being and such perceptions of medical students at the University of the Philippines College of Medicine (UPCM).

The study uses a quantitative approach using a subset of secondary data from a college-wide survey online that was disseminated, through convenience sampling, to medical students from October 3, 2018 to December 3, 2018. A total of 432 responses were included in the analysis, out of the total student population of the included learning unit levels of 809. Participants were grouped based on their entry into medical school, either through the Integrated Liberal Arts and Medicine (INTARMED) program or lateral entry. Exclusion criteria comprised responses from Learning Unit I-II (pre-medical proper) students and incomplete survey sets. Responses were interpreted using established scales such as the World Health Organization Well-Being Index (WHO-5), Perceived Stress Scale-4 (PSS-4), and Oldenburg Burnout Inventory-Medical Student (OLBI-MS). Data analysis involved statistical techniques including one-way ANOVA and independent samples t-test using Statistical Package for the Social Sciences (SPSS).

The findings suggest that medical students at UPCM generally find the administrative and academic systems satisfactory, but express concerns about inadequate educational resources and infrastructure, especially as they progress through their studies and engage more with clinical settings like the Philippine General Hospital (PGH). As students advance through the program, there are different patterns for wellbeing outcomes, including decreasing perceived stress and increasing burnout. In particular, LU IV and LU VII students reported lower well-being and higher burnout levels, respectively. This is potentially due to heavier workloads and clinical responsibilities. Lateral entrants, who are older and typically enter with prior degrees, tend to have higher well-being and lower burnout compared to INTARMED students, suggesting age and previous educational experience may play a role in adjustment and coping mechanisms.

Overall, the study highlights the medical students’ generally satisfactory perception of medical educational aspects, as well as the patterns of wellbeing throughout their medical college experience. Furthermore, it identifies different areas for improvement to ensure effective education and student mental health. By analyzing trends across different year levels, the study provides insights for interventions and program refinements, while also suggesting avenues for further research to assess student experiences over time.

BACKGROUND AND OBJECTIVE

Within a decentralized health system, barangay health workers (BHWs) are often the first point of contact for Filipinos seeking care. Despite their importance, BHWs are neglected in the health value chain. The study seeks to examine the lived experiences of BHWs, particularly their journey in navigating their roles within the community and the health system that encompasses their day-to-day realities, challenges, motivations, and the meanings they derive from their work.

The study draws on seven focus group discussions (FGDs) with BHWs (n=50), residents (n=7), and local government officials and health workers (n=7) of San Miguel, Bulacan. The qualitative data collected were analyzed using thematic analysis.

Findings show that BHWs perform many roles, which are not limited to health and are dependent on orders from their superiors. Guidelines are vague in appointing BHWs, with personal connections valued more than technical qualifications. Their accreditation is hardly conferred any significance. There is also a lack of formal and structured training. The informality of these processes leads to an absence of quality assurance on rendered health services. The non-provision of incentives and benefits stipulated in RA 7883 also places their health and lives at risk. Furthermore, BHW’s commitment to serve is used to excuse the inadequacy of their compensation and excessive workload.

BHWs take on diverse roles, from community organizers to healthcare providers, and are confronted with significant challenges encompassing politicization, inadequate training, and insufficient compensation. The study concludes with policy recommendations to improve the conditions of the neglected BHWs, with particular attention to coordinating, capacitating, compensating, career pathing, and connecting them to the health system.

OBJECTIVE

This study assessed the level of health system responsiveness of Rural Health Units (RHUs) in Cagayan Valley Region along seven domains of responsiveness namely dignity, autonomy, confidentiality, choice of provider, prompt attention, communication, and quality of basic amenities, and five core components of the health system namely health governance, health human resource, health information system, access to medicines and technology, and service delivery.

A cross-sectional research design was adopted using survey as the primary means of data collection using a researcher-developed questionnaire. The study was conducted in RHUs of 15 identified municipalities in the region. The municipalities were chosen based on their low performance in the LGU health score cards for 2019. A total of 618 clients and 235 health workers were included in the study. Frequency, percentage, and mean were used to analyze the profile and level of health system responsiveness. T test and one-way ANOVA were used to test significant differences.

The results showed that the RHUs included in the study have very good level of health system responsiveness, with overall percentage scores ranging from 73.55 to 88.08, in all domains assessed. However, choice of providers within the facilities (62.71%) and access to medicine and technology (77.45%) were the least responsive among all the identified domains. Significant differences in the clients’ assessment of the responsiveness of the RHUs were seen when grouped according to their sex, age, educational attainment, income level, overall level of health, frequency of visits, and distance of home to facility. The RHUs’ location, whether in an urban or rural area, number of staff, and number of barangays catered also were found to determine the level of health system responsiveness. Moreover, not all RHUs were able to comply with basic requirements of the Department of Health specifically along the services offered.

It can be concluded therefore that the RHUs, despite the limitations in certain aspects are still able to meet the expectations of the clients and health workers in the delivery of health services. However, in order to maximize responsiveness of these facilities, DOH requirements for these facilities should be met.

Human ; Health ; Mental Health ; Universities

Traditional Chinese medicine(TCM) resources are the essential material foundation for the development of TCM. The national survey of TCM resources serves as a periodic summary of these resources, ensuring the continuity, prosperity, and development of TCM in China. Since 1949, four national surveys of TCM resources have been conducted. The fourth survey incorporated an investigation into traditional knowledge related to TCM resources, including the traditional medicinal knowledge of Chinese ethnic minorities, with the goal of systematically exploring, preserving, and inheriting this knowledge. This manuscript provides an overview of the basic findings from the first three national surveys of TCM resources, while also clarifying the concepts, categories, forms, carriers, and acquisition pathways of traditional knowledge related to TCM resources. A preliminary summary of the findings from traditional knowledge investigations reported in current literature is also presented. Based on the fourth survey, this manuscript emphasizes the urgency of developing public medical knowledge through empirically-based investigations, the excavation, and compilation of traditional knowledge. It also outlines the potential for conducting "precise" investigations based on first-hand data obtained from the survey, as well as facilitating the discovery and evaluation of new medicines using traditional knowledge related to ethnic minority medicinal practices. This manuscript is expected to provide valuable insights for promoting the health and industrial development of ethnic minority populations in the post-"survey" phase.
Humans ; Medicine, Chinese Traditional ; China/ethnology* ; Minority Groups ; Ethnicity ; Drugs, Chinese Herbal/therapeutic use* ; Health Knowledge, Attitudes, Practice/ethnology* ; Surveys and Questionnaires

Cardiovascular diseases and psychological disorders represent two major threats to human physical and mental health. Research on electrocardiogram (ECG) signals offers valuable opportunities to address these issues. However, existing methods are constrained by limitations in understanding ECG features and transferring knowledge across tasks. To address these challenges, this study developed a multi-resolution feature encoding network based on residual networks, which effectively extracted local morphological features and global rhythm features of ECG signals, thereby enhancing feature representation. Furthermore, a model compression-based continual learning method was proposed, enabling the structured transfer of knowledge from simpler tasks to more complex ones, resulting in improved performance in downstream tasks. The multi-resolution learning model demonstrated superior or comparable performance to state-of-the-art algorithms across five datasets, including tasks such as ECG QRS complex detection, arrhythmia classification, and emotion classification. The continual learning method achieved significant improvements over conventional training approaches in cross-domain, cross-task, and incremental data scenarios. These results highlight the potential of the proposed method for effective cross-task knowledge transfer in ECG analysis and offer a new perspective for multi-task learning using ECG signals.
Humans ; Electrocardiography/methods* ; Mental Health ; Algorithms ; Signal Processing, Computer-Assisted ; Machine Learning ; Arrhythmias, Cardiac/diagnosis* ; Cardiovascular Diseases ; Neural Networks, Computer ; Mental Disorders

Chemical exposure during prenatal development has significant implications for both maternal and child health. Compared to blood, saliva is a non-invasive and less resource-intensive, alternative. Given the temporal variability of xenobiotic metabolites (XM), repeated sampling is essential. Therefore, saliva offers a valuable tool for the longitudinal assessment of prenatal exposomes. Despite its potential, no studies have explored saliva for XM measurement. This study pioneered using saliva to assess XM detectability and investigate the associations between prenatal XM and endogenous metabolomes in pregnant women. Saliva samples were analysed using mass spectrometry from 80 pregnant women at 24-34 weeks gestation. Metabolomes and exposomes were annotated using the Human Metabolome and U.S. Environmental Protection Agency databases. Metabolome-XM associations were clustered using Glay community clustering. Linear regression models, adjusted for age, estimated associations between catecholamines and XMs. XM levels were validated in a cohort of women (n = 14) with and without preeclampsia. Our study identified 582 metabolomes and 125 XM in saliva, demonstrating its potential as a matrix for exposure measurement. After false discovery rate correction, 18 109 significant metabolome-XM associations were identified. Community clustering revealed 37 connected clusters, with the largest cluster (238 nodes) enriched in tyrosine and catecholamine metabolism. Food-contact-chemicals and food-additives were significantly associated with higher catecholamine and their metabolite levels. Subgroup analyses revealed higher concentrations of these chemicals in women with preeclampsia compared to healthy controls. This study demonstrates that saliva contains valuable molecular data for measuring exposomes. Food-related chemicals were associated with higher catecholamine levels, which may be relevant to the prevalence of hypertensive crises in pregnancy.
Humans ; Female ; Pregnancy ; Saliva/metabolism* ; Pre-Eclampsia/metabolism* ; Xenobiotics/analysis* ; Adult ; Metabolome ; Maternal Health ; Mass Spectrometry

With the growing emphasis on maternal and child oral health, the significance of managing oral health across preconception, pregnancy, and infancy stages has become increasingly apparent. Oral health challenges extend beyond affecting maternal well-being, exerting profound influences on fetal and neonatal oral development as well as immune system maturation. This expert consensus paper, developed using a modified Delphi method, reviews current research and provides recommendations on maternal and child oral health management. It underscores the critical role of comprehensive oral assessments prior to conception, diligent oral health management throughout pregnancy, and meticulous oral hygiene practices during infancy. Effective strategies should be seamlessly integrated across the life course, encompassing preconception oral assessments, systematic dental care during pregnancy, and routine infant oral hygiene. Collaborative efforts among pediatric dentists, maternal and child health workers, and obstetricians are crucial to improving outcomes and fostering clinical research, contributing to evidence-based health management strategies.
Humans ; Pregnancy ; Female ; Infant ; Consensus ; Mouth Diseases/therapy* ; Pregnancy Complications/therapy* ; Oral Health ; Infant, Newborn ; Delphi Technique ; Oral Hygiene