Association between Hepatitis B Surface Antigen Seropositivity and Metabolic Syndrome.
10.4082/kjfm.2014.35.2.81
- Author:
Tae Heum CHUNG
1
;
Moon Chan KIM
;
Chang Sup KIM
Author Information
1. Department of Family Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea. jeongth@uuh.ulsan.kr
- Publication Type:Original Article
- Keywords:
Hepatitis B;
Metabolic Syndrome;
Triglycerides
- MeSH:
Cardiovascular Diseases;
Cross-Sectional Studies;
Female;
Hepatitis B Surface Antigens*;
Hepatitis B virus;
Hepatitis B*;
Hepatitis*;
Humans;
Hypertriglyceridemia;
Korea;
Logistic Models;
Male;
Risk Factors;
Triglycerides;
Ulsan;
Young Adult
- From:Korean Journal of Family Medicine
2014;35(2):81-89
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Infection with hepatitis B virus (HBV) may be a risk factor for cardiovascular disease. We investigated the relationship between HBV infection and metabolic syndrome. METHODS: We performed a cross-sectional study of 9,474 Korean men and women who were at least 20 years old and who underwent a routine health check-up at Ulsan University Hospital in Ulsan, South Korea between March 2008 and February 2009. The associations of hepatitis B surface antigen (HBsAg) seropositivity with the presence of metabolic syndrome and its components were investigated by logistic regression analysis. Data were analyzed separately for males and females. RESULTS: HBsAg seropositivity was significantly negatively associated with hypertriglyceridemia and metabolic syndrome in men (odds ratio [OR], 0.39; 95% confidence interval [CI], 0.29 to 0.50; P < 0.001 and OR, 0.75; 95% CI, 0.57 to 0.98, P = 0.033). In women, HBsAg seropositivity was also significantly negatively associated with hypertriglyceridemia, but not with metabolic syndrome (OR, 0.40; 95% CI, 0.17 to 0.91; P = 0.029 and OR, 0.80; 95% CI, 0.38 to 1.66, P = 0.545). CONCLUSION: HBV infection was significantly negatively associated with hypertriglyceridemia and metabolic syndrome in men and hypertriglyceridemia in women.
