Integracide K: A New Tetracyclic Triterpenoid from Desmodium uncinatum (Jacq.) DC. (Fabaceae).
10.20307/nps.2017.23.2.113
- Author:
Borice Tapondjou TSAFACK
1
;
Beaudelaire Kemvoufo PONOU
;
Rémy Bertrand TEPONNO
;
Raymond Ngansop NONO
;
Kristina JENETT-SIEMS
;
Matthias F MELZIG
;
Hee Juhn PARK
;
Léon Azefack TAPONDJOU
Author Information
1. Department of Chemistry, Faculty of Science, University of Dschang, Box 67, Dschang, Cameroon. tapondjou2001@yahoo.fr
- Publication Type:Original Article
- Keywords:
Desmodium uncinatum;
Fabaceae;
Tetracyclic triterpenoid;
Integracide;
Isoflavonoids
- MeSH:
Cameroon;
Ergosterol;
Fabaceae;
Methanol;
Plants;
Sodium
- From:Natural Product Sciences
2017;23(2):113-118
- CountryRepublic of Korea
- Language:English
-
Abstract:
A new tetracyclic triterpenoid [4,4,24-trimethylcholesta-Δ(8,9;14,15;24,28)-trien-3β,11β,12α-triol-12-acetate, 3-sulfate] sodium salt (1), together with eight known compounds including ergosterol 5α,8α-endoperoxide (2), 1,9-dihydroxy-3-methoxy-2-methylpterocarpan (3), 3-O-β-D-2-acetyl-amino-2-deoxyglucopyranoxyloleanoic acid (4), hydnocarpin (5), derrone (6), isovitexin (7), erythrinin C (8), and 5,4'-dihydroxy-2''-hydroxyisopropyldihydrofurano [4,5:7,8]-isoflavone (9), were isolated from the EtOAc soluble fraction of the methanol extract of aerial part of Desmodium uncinatum collected in the western highland of Cameroon. The structures of these compounds were established by comprehensive interpretation of their spectral data mainly including 1D- (¹H and ¹³C), 2D-NMR (¹H-¹H COSY, HMQC, HMBC) spectroscopic and ESI-TOF-MS mass spectrometric analysis. The isolation of an integracide-like compound from plant origin is a very unusual finding.
