Progress in clinical application of urgent lung transplantation
10.3969/j.issn.1674-7445.2021.05.006
- VernacularTitle:紧急肺移植的临床应用进展
- Author:
Haoxuan LI
1
;
Heng HUANG
;
Haoji YAN
;
Hongtao TANG
;
Xiangyun ZHENG
;
Han ZHANG
;
Qinchun QIAN
;
Kaiyuan JIANG
;
Dong TIAN
Author Information
1. Heart and Lung Transplant Research Laborary, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China
- Publication Type:Research Article
- Keywords:
Lung transplantation;
Shortage of donor lung;
Donor lung allocation;
Conventional mechanical ventilation;
Extracorporeal membrane oxygenation;
Extracorporeal life support;
Chronic obstructive pulmonary disease;
Restrictive lung disease
- From:
Organ Transplantation
2021;12(5):539-
- CountryChina
- Language:Chinese
-
Abstract:
Lung transplantation is the only effective treatment of end-stage lung diseases. Nevertheless, shortage of donor lungs has become increasingly prominent worldwide. A large quantity of patients died while waiting for lung transplantation. Urgent lung transplantation is a prioritized allocation strategy for donor lung transplantation according to the urgency of diseases, aiming to shorten the waiting time for donor lungs and reduce the fatality of patients on the waiting list for lung transplantation. However, no consensus has been reached worldwide on the definition, criteria and application of the terminology of urgent lung transplantation. In addition, the survival and net benefits of lung transplant recipients based on this allocation system are still controversial. On the basis of previous clinical research on urgent lung transplantation, the definition criteria, risk factors, survival outcomes, limitations and optimization measures were explicitly elucidated in this article, aiming to provide theoretical reference for comprehensive evaluation of the feasibility of urgent lung transplantation and further optimizing the allocation system of donor lungs.
