Evaluation of the Effect of Lentinula Edodes Mycelia Extract on Immune Function in Healthy Subjects Placebo-controlled, Parallel-group Study
- VernacularTitle:シイタケ菌糸体抽出物の健常者に対する免疫機能に及ぼす影響検証：プラセボ対照並行群間比較試験
- Author:
Shota KAJIYAMA
1
;
Yasunori MATSUI
1
Author Information
- Keywords: immune function; NK cell activity; fatigue; lentinula edodes mycelia; healthy subjects
- From:Japanese Journal of Complementary and Alternative Medicine 2020;17(2):105-110
- CountryJapan
- Language:Japanese
- Abstract: In this study, we examined the effects of Lentinula edodes mycelia (LEM) on fatigue and immune function in healthy subjects. 22 people were randomly assigned in a 1:1 ratio to the LEM ingestion group and the placebo group. Daily oral ingestion of LEM for 4 weeks (600 mg/day) significantly improved the VAS fatigue score compared with before treatment (p<0.01). Additionally, NK cell activity was increased by ingestion of LEM (p<0.01) and was higher level compared to the placebo group (p<0.05). These results indicate that oral ingestion of LEM may improve the feeling of fatigue and immune function.
