Recent advances in using of stem cell-derived extracellular vesicles in treating central nervous system diseases
10.3969/j.issn.1674-8115.2020.01.022
- Author:
Zheng-Hui HE
1
Author Information
1. School of Clinical Medicine, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University
- Publication Type:Journal Article
- Keywords:
Alzheimer’s disease;
Central nervous system injury;
Neuroglioma;
Stem cell-derived extracellular vesicles (SC-EVs)
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2020;40(1):134-138
- CountryChina
- Language:Chinese
-
Abstract:
Stem cell-derived extracellular vesicles can regulate functions of targeting cells in lesions and have fewer risks in treating diseases. In central nervous injury lesions, stem cell-derived extracellular vesicles can promote neurogenesis and angiogenesis and regulate nervous inflammation, which promotes the recovery of the nerve injury. Stem cell-derived extracellular vesicles can ease Aβ protein-related neuron damage in Alzheimer's disease. Stem cell-derived extracellular vesicles also can deliver microRNA and chemotherapeutic agents to neuroglioma cells. This review introduces recent advances in using stem cell-derived extracellular vesicles in treating central nervous system diseases.
