Analysis of clinical features and prognostic factors of meconium peritonitis
10.3969/j.issn.1674-8115.2020.05.016
- VernacularTitle: 胎粪性腹膜炎的临床特征及预后相关因素分析
- Author:
Peng-Peng WANG
1
Author Information
1. Department of Pediatric Intensive Care Unit, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
- Publication Type:Journal Article
- Keywords:
C-reactive protein;
Meconium peritonitis;
Prenatal diagnosis;
Prognosis
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2020;40(5):662-665
- CountryChina
- Language:Chinese
-
Abstract:
Objective • To analyze the clinical features of meconium peritonitis (MP) and the related factors influencing its prognosis. Methods • Fiftyfour patients with MP who received surgical intervention at department of pediatric intensive care unit, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine from May 2006 to May 2018 were retrospectively reviewed, and divided into complication group (n=24) and non-complication group (n=30). Risk factors of the two groups after operation were analyzed, including general condition, prenatal diagnosis and preoperative value of C-reactive protein (CRP), independent-samples t test, χ2 test or Fisher's exact test. Results • Compared with the non-complication group, days of admission and operation after birth were longer; the gestational age and the birth weight were lower (all P<0.05) in the complication group; the CRP value of the complication group was higher than that of the non-complication group (P=0.048). The prenatal diagnosis percentage of the non-complication group was higher than that of the complication group (P=0.039). However, there was no statistical significance in gender, Apgar score, surgical procedure, delivery type and prenatal ultrasound findings. Conclusion • Prenatal ultrasound detection with MP and early surgical treatment can improve the prognosis, and the preoperative inflammation level has a certain predictive value for the prognosis of children.
