Predictive value of dynamic contrast-enhanced MRI of original plaque on carotid artery in-stent restenosis
10.3969/j.issn.1674-8115.2020.07.007
- VernacularTitle: 术前颈动脉斑块动态增强磁共振成像对支架置入后再狭窄发生的预测价值
- Author:
Xiao-Qian GE
1
Author Information
1. Department of Medical Imaging, Shandong Provincial Western Hospital
- Publication Type:Journal Article
- Keywords:
Atherosclerosis;
Carotid artery;
Dynamic contrast-enhanced MR imaging (DCE-MRI);
In-stent restenosis
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2020;40(7):902-907
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the value of dynamic contrast-enhanced MR imaging (DCE-MRI) of original plaque to predict carotid artery in-stent restenosis (ISR). Methods: Forty cases of the patients with carotid atherosclerosis who were to undergo the carotid artery stenting (CAS) were included in this study. All participants underwent vessel wall MR imaging (VW-MRI) and DCE-MRI within one week before CAS. Carotid digital subtraction angiography (DSA) were performed at the sixth month to reassess the stenosis of stent. The correlation between DCE-MRI and ISR was evaluated. Results: The level of Ktran in ISR group was significantly higher than that in non-ISR group (P=0.000), and so was the vP (P=0.037). Ktrans could independently predict ISR (OR=1.43, 95%CI 1.17-1.56, P=0.012), and the cut-off value of Ktrans was 0.09 min-1 (sensitivity=100%, specificity=87.5%). Conclusion: Intraplaque inflammation may lead to excessive intimal hyperplasia after ISR. Ktrans could be a risk predictor of ISR with high sensitivity and specificity. DCE-MRI could be an effective tool to predict ISR.
