Follow-up of thyroid ultrasonography in patients with hemodialysis
10.12701/yujm.2017.34.1.69
- Author:
Hyun Jung KIM
1
;
Bo Ra KIM
;
Yeong Mi SEO
;
Yoon Young CHO
;
Jong Ha BAEK
;
Kyong Young KIM
;
Soo Kyung KIM
;
Seung Hoon WOO
;
Jung Hwa JUNG
;
Jaehoon JUNG
;
Jong Ryeal HAHM
Author Information
1. Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Korea. jrhahm@gnu.ac.kr
- Publication Type:Original Article
- Keywords:
Goiter;
Hemodialysis;
Thyroid nodule;
Ultrasonography
- MeSH:
Follow-Up Studies;
Goiter;
Humans;
Hypothyroidism;
Logistic Models;
Medical Records;
Parathyroid Hormone;
Prospective Studies;
Renal Dialysis;
Renal Insufficiency, Chronic;
Risk Factors;
Thyroid Function Tests;
Thyroid Gland;
Thyroid Nodule;
Ultrasonography
- From:Yeungnam University Journal of Medicine
2017;34(1):69-74
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Chronic kidney disease is considered a risk factor for thyroid nodules as well as thyroid dysfunction such as hypothyroidism. Among patients on hemodialysis, we assessed the size of thyroid nodule and goiter at baseline and 1 year later with ultrasonography.METHODS: We prospectively selected 47 patients with hemodialysis at January 2012 and reviewed their medical records. We checked goiter and thyroid nodules at January 2012 and December 2012.RESULTS: In the hemodialysis patients (n=47), 24 patients (51.1%) had thyroid nodules and 33 patients (70.2%) had goiter at baseline. Parathyroid hormone (PTH) was higher in patients with thyroid nodules (204.4±102.9 vs. 129.9±93.6 pg/mL, p=0.01). Thyroid ultrasonography was conducted in 29 patients after 1 year. The thickness of the thyroid isthmus increased (2.8±1.6 vs. 3.2±1.9 mm, p=0.003), but the number of nodules did not change (1.2±1.9 vs. 1.4±2.0, p=0.109). PTH was associated with the enlargement of thyroid nodules significantly through logistic regression analysis.CONCLUSION: Thyroid goiter and nodules in hemodialysis patients were more prevalent than in the general population. PTH influenced the production of thyroid nodules in hemodialysis patients. Regular examination with thyroid ultrasonography and thyroid function test should be considered in hemodialysis patients.