A case of Huntington disease first presenting with psychotic symptoms

VernacularTitle:以精神病症状为首发表现的亨廷顿病个案报告
Author: Pei LIU ¹ ; Ying LIANG ; Weizhong XIAO ; Hongwei GU ; Cui LIU
Author Information

1. 北京大学精神卫生研究所
Keywords: delusion; suicide; Huntingdon disease; case report
From: Chinese Mental Health Journal 2018;32(2):101-105
CountryChina
Language:Chinese
Abstract: This was a case of 32-year-old HAN woman admitted to psychiatric hospital presenting for social withdraw,deluded ideas,unexplained runaways and suicide behaviors.She was diagnosed as schizophrenia and brought to the psychiatrist for unbearable behavior problems by her family.When admitted to hospital the patient showed significant depressive symptoms and delusions with influent speech,hypotonia,involuntary movements of distal limb and ataxia.Cognitive tests revealed multiple deficits.Consulted with the neurologist,a diagnosis of organic mental disorder was suggested.Magnetic resonance imaging showed slight widen of lateral ventricles and mild atrophy of caudate nucleus and cortex of frontal lobe.The family history was re-collected and found three family members shared the influent speech and ataxia.Then the clinical diagnose of Huntingdon Disease was made and validated with gene tests.