Advance in Model Establishment for Denervated Skeletal Muscle Atrophy (review)
10.3969/j.issn.1006-9771.2018.01.015
- VernacularTitle:失神经性肌萎缩动物模型制备方法的研究进展
- Author:
Dan Dan- ZHAO
1
;
Lin Cheng- TANG
;
Qin Si- HUANG
;
Ao LUO
;
Ning An- ZHANG
;
Yu Hui- AN
;
Jia Meng- WU
;
Cheng-Fang TAN
Author Information
1. 重庆医科大学中医药学院
- Keywords:
denervated skeletal muscle atrophy;
animal model;
establishment;
review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2018;24(1):80-83
- CountryChina
- Language:Chinese
-
Abstract:
The skeletal muscle atrophy could be induced by the injury of nerve. According to the source of denervated skeletal mus-cle atrophy, it could be divided into exogenous muscle atrophy and endogenous muscle atrophy. In recent years, the ex-ogenous muscle atrophy models are mainly established by operating, physically injuring or chemically injuring, while the endogenous muscle atrophy models are mainly established by the transgenic animals of amyotrophic lateral sclero-sis. The selection and optimazation of animal models are crucial for the basic studies of denervated skeletal muscle atro-phy.
