Optimizatoin of extraction technology of compound purgative Moringa Oleifera based on central composite design and response surface method
10.3760/cma.j.issn.1673-4246.2018.03.013
- VernacularTitle:中心复合设计-响应面法优化辣木叶通便复方提取工艺
- Author:
Mengwei LI
1
;
Wenhong GU
;
Yanhua JI
;
Jun HE
;
Xing HAN
;
Xingfen LONG
;
Yang LIU
Author Information
1. 100102,北京中医药大学中药学院
- Keywords:
Extraction;
Technology improving (TCD);
Central composite design-response surface method;
Compound purgative Moringa Oleifera
- From:
International Journal of Traditional Chinese Medicine
2018;40(3):246-250
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize the extraction technology of Compound purgative Moringa Oleifera by central composite design-response surface method. Methods The content of isoquercetin and astragalin, the yield of dry extract and overall desirability (OD) were used as the evaluation indexes; the factors such as water addition, extraction times and time for extraction were employed to optimize extraction technology of central composite design-response surface method. Results Optimal extraction technology was as follows: 3 times extracted with 10-fold the amount of water for 1 h each time. Conclusions Central composite design-response surface method was suitable for optimizing extraction technology of compound purgative Moringa Oleifera.
