The role of carnosine on the oxidation reaction in vitro
10.19405/j.cnki.issn1000-1492.2018.06.033
- VernacularTitle:肌肽在体外氧化反应中的作用
- Author:
Shiqi ZHANG
1
;
Li XIA
;
Qiu ZHANG
Author Information
1. 安徽医科大学第一附属医院内分泌科
- Keywords:
carnosine;
anti-oxidant;
pro-oxidant;
in vitro study
- From:
Acta Universitatis Medicinalis Anhui
2018;53(6):979-983
- CountryChina
- Language:Chinese
-
Abstract:
In this study, HRP or FeCl3were used as the catalysts in MTT, TMB and Mino reaction system, the effects of carnosine on the oxidation reaction were evaluated respectively. Indeed, carnosine was a pro-oxidant in luminol reaction, however an anti-oxidant in MTT assay. Once TMB was its substrate, carnosine was neutral in oxi-dation. Thus, it is supposed that the oxidative property of carnosine depends on the substrates.
