Protective effect of ginkgolide on renal failure induced by adenine
- VernacularTitle:银杏内酯对腺嘌呤致肾功能不全的保护作用研究
- Author:
Shiling ZHANG
;
Hongxiang LOU
;
Congran LI
;
- Publication Type:Journal Article
- Keywords:
ginkgolide;
adenine;
renal failure;
rat
- From:
Chinese Traditional Patent Medicine
1992;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the protective effect of ginkgolide on rat's renal failure induced by adenine.Methods: The chronic renal functional failure model of rat was established with adenine. Its urea nitrogen (BUN), reatinine (Crea), Cholesterin (CH), total protein (TP), and albumin (ALP) in blood were determined. The pathologic changes were also observed. Results: Ginkgolide has effects on renal failure caused by adenine. Low and high dose groups decrease BUN. Crea, low dose group decrese CH, high dose group increase numbers of kindney glomerulus.Conclusion: Ginkgolide has protective effect on rat's renal failure induced by adenine.