Therapeutic effect of "shen-bing N05" on adenine-induced chronic nephritis in rats
- VernacularTitle:肾病5号对腺嘌呤致大鼠慢性肾炎模型的治疗研究
- Author:
Quan-Rong ZHOU
;
Shi-Wen DAI
;
Xu-Ping WANG
;
Wei-Min ZHANG
;
Shu-Yan XU
;
Cheng-Wei XIAO
;
- Publication Type:Journal Article
- Keywords:
Shen-bing N0 5";
chronic nephritis;
Adenine
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
1999;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim The therapeutic effect of "shen-bing NQ 5", a preparation of traditional Chi-nese medicine on adenine-induced chronic nephritis in rats was studied. MethodsChronic nephritis in rats was induced by giving adenine 80 mg?kg-1?d-1 orally. Themodel rats were treated by "shen-bing No 5" in different dosages. Levels of urea ni-trogen(BUN), creatinine (Cr), total protein(TP), and Na+ in serum and or urine weredetected and the changes of kidney were obseraed. Results The "shen-bing No 5"markedly lowered the levels of urine protein in 24 hours, BUN in urine and BUN, Na+in serum (P