Research progress in skin advanced glycation end-products and diabetic kidney disease
10.3969/j.issn.1006-6187.2017.10.017
- VernacularTitle:皮肤糖基化终产物荧光检测在糖尿病肾脏疾病中的研究进展
- Author:
Ziwei WANG
1
;
Junqing ZHANG
;
Xiaohui GUO
Author Information
1. 100034,北京大学第一医院内分泌科
- Keywords:
Advanced glycation end-products;
Diabetic kidney disease;
Skin autofluorescence
- From:
Chinese Journal of Diabetes
2017;25(10):938-941
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic kidney disease(DKD) is one of the major complications of diabetes mellitus.The formation of advanced glycationend-products (Advanced Glycation End-products,AGEs) has been widely accepted to play a crucial role in the pathogenesis of diabetic nephropathy.It has been reported that the skin autofluorescence test of AGEs can better reflect the AGEs accumulation in vivo,thus providing stronger evidence in predicting diabetic nephropathy.As a noninvasive,convenient and steady measure,skin autofluorescence will be widely applied in the assessment and monitoring the progress of diabetic nephropathy in the future.Here,we reviewed the research progress in skin AGEs and diabetic nephropathy.
