Progress in research on JAK/STAT3 signaling pathway regulating tumor and related biological functions
- VernacularTitle:JAK/STAT3信号通路调控肿瘤及其相关生物功能的研究进展
- Author:
jin Jin ZHANG
1
;
Hui TANG
Author Information
1. 昆明理工大学附属医院 临床基础医学研究所
- Keywords:
JAK/STAT3 signaling pathway;
neoplasms;
cell apoptosis
- From:
Basic & Clinical Medicine
2017;37(10):1456-1460
- CountryChina
- Language:Chinese
-
Abstract:
JAK/STAT3 signal pathway is an important intracellular signal transduction pathway. It plays important roles in cell apoptosis and proliferation by affecting the activity of downstream effector molecules,and also induces embryonic development,liver regeneration,glycolysis and inflammation,epithelial-mesenchymal transition and an-giogenesis and a series of biogenesis process,closely related to the development of human cancer.
