Research Progress of Improving Effect of Chlorogenic Acid on Alzheimer's Disease
10.3870/j.issn.1004-0781.2017.11.019
- VernacularTitle:绿原酸改善阿尔茨海默病研究进展
- Author:
Yinle YAO
1
;
Chunmei WANG
Author Information
1. 遵义医学院珠海校区生理教研室
- Keywords:
Chlorogenic acid;
Alzheimer's disease;
Oxidative stress;
Neuroinflammation
- From:
Herald of Medicine
2017;36(11):1287-1290
- CountryChina
- Language:Chinese
-
Abstract:
Chlorogenic acid ( CGA) was known as polyphenolic compounds with a wide range of biological activities. It was extracted from Eucommiaulmoides Oliv plant.It has attracted considerable attention because of its good anti-inflammatory and antioxidant activity. This review aims to summarize neuroprotective activities of chlorogenic acid on Alzheimer ' s disease via improving learning and memory ability, inhibiting β-amyloid-induced neurotoxicity, relieving mitochondrial injury and anti-apoptotic pathways.
