Cancer Invasion to Laryngeal Cartilage after Radiation Therapy in Salvaged Laryngectomy Specimens.
- Author:
Kyong Myong CHON
1
;
Soo Geun WANG
;
Eui Kyung GOH
;
Hwan Jung ROH
;
Seu Gyu KIM
;
Woo Young SHIM
;
Kang Suek SUH
Author Information
1. Department of Otolaryngology, College of Medicine, Pusan National University, Pusan, Korea.
- Publication Type:Original Article
- Keywords:
Salvage laryngectomy;
Laryngeal cartilage invasion;
Whole organ section
- MeSH:
Arytenoid Cartilage;
Cartilage;
Cricoid Cartilage;
Epiglottis;
Head;
Incidence;
Laryngeal Cartilages*;
Laryngectomy*;
Neck;
Organ Preservation;
Quality of Life;
Radiotherapy;
Retrospective Studies;
Thyroid Cartilage;
Thyroid Gland;
Tomography, X-Ray Computed
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
1997;40(11):1571-1577
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Many head and neck surgeons preferred the radiotherapy as a first choice in treating early laryngeal carcinoma(T1, T2) to surgical operation because of the relatively high curability(80-90%), organ preservation and better quality of life. If radiotherapy failed, some surgeons perform total laryngectomy as salvage operation, but others prefer to perform partial laryngectomy, which is increasing in tendency. OBJECTIVE: To investigate the pattern of cancer invasion to the laryngeal cartilages using salvage laryngectomized cancer specimens which had recurred after radiotherapy. MATERIALS & METHOD: Preoperative computerized tomograpy images were retrospectively compared to postoperative salvage laryngectomized cancer specimens which had recurred after radiotherapy 13 cases from March, 1985 to February, 1994. RESULTS: 1) In laryngeal cacer recurred after radiotherapy, incidence of cartilage invasion was not in early supragolttic cancer. but all in advanced supraglottic cancer, and 3cases of 5 cases(60.0%) in early glottic cancer, 4cases of 5 cases(80.0%) in advanced glottic cancer. 2) The order of laryngeal cartilage invasion was the first thyroid cartilage(61.5%), the second arytenoid cartilage(30.7%), and the third cricoid cartilage(23.1%). 3) The diagnostic accuracy of preoperative CT scan for laryngeal cartilage invasion was 66.7% in thyroid cartilage, 55.6% in arytenoid cartilage, 55.6% in cricoid cartilage, and 100% in epiglottis. CONCLUSION: Selection of partial laryngectomy as salvage operation should be considered carefully.