Metabolic Characteristics of Insulin Secretion and Insulin Sensitivity in Isolated Postchallenge Hyperglycemia
- VernacularTitle:单纯餐后高血糖型糖尿病的胰岛素分泌与敏感性
- Author:
jing-yan, TIAN
;
yan-yun, GU
;
xian-ling, ZHANG
;
hong, LI
;
wei-bin, ZHOU
;
hong-li, ZHANG
;
xiao, WANG
;
tian-hong, LUO
;
guo, LI
;
min, LUO
- Publication Type:Journal Article
- Keywords:
type 2 diabetes mellitus;
early-phase insulin secretion;
insulin sensitivity index
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the metabolic characteristics of insulin secretion and insulin sensitivity in isolated postchallenge hyperglycemia(IPH) and to clarify the factors responsible for the development of IPH. Methods(Eight hundred) and fifty subjects were classified into the following three groups based on the results of a 75-g oral glucose tolerance test(OGTT): normal glucose tolerance(NGT),n=557;isolated impaired glucose tolerance(iIGT),n=146;and IPH,n=147.Insulin secretion(insulinogenic index) and insulin sensitivity(insulin sensitivity index) were identified in the three groups. Results From NGT to iIGT and IPH in these subjects,the insulinogenic index and insulin sensitivity index were gradually decreased(P
