Study Progress of Low-Grade Inflammation in Pathogenesis of Children with Obesity and Insulin Resistance
- VernacularTitle:超体质量及肥胖儿童低度炎性反应与胰岛素抵抗的研究进展
- Author:
yan-ming, LIU
;
guang-min, NONG
- Publication Type:Journal Article
- Keywords:
obesity;
insulin resistance;
low-grade inflammation;
child
- From:Journal of Applied Clinical Pediatrics
2006;0(14):-
- CountryChina
- Language:Chinese
-
Abstract:
Obesity has been a world-wide growing health problem in children and adolescents,insulin resistance plays a pivotal role in the pathogenesis of obesity-associated complications,the mechanism is still unknown.There is growing evidence that obesity is associated with low-grade inflammation in youth.The onset of low-grade inflammation in obesity may be associated with the inflammatory cytokine secreted by adipose tissue,local Monocyte/Macrophage system and role of oxidative stress.The study of inflammatory cytokines in pathogenesis of obesity and insulin resistance will help to develop new treatment strategies to prevent obesity and obesity-associated complications.
